Zobrazeno 1 - 10
of 4 242
pro vyhledávání: '"Riboside"'
Autor:
Mariano Marín-Blázquez, Jordi Rovira, María José Ramírez-Bajo, Rubén Zapata-Pérez, Rubén Rabadán-Ros
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-30 (2024)
Abstract Cardiorenal diseases represent a complex interplay between heart failure and renal dysfunction, being clinically classified as cardiorenal syndromes (CRS). Recently, the contributions of altered nicotinamide adenine dinucleotide (NAD+) metab
Externí odkaz:
https://doaj.org/article/26b3ad75bf254b6cae8dbe94765d7015
Autor:
Helena Borland Madsen, Claudia Navarro, Emilie Gasparini, Jae-Hyeon Park, Zhiquan Li, Deborah L. Croteau, Vilhelm A. Bohr
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionDuring aging, many cellular processes, such as autophagic clearance, DNA repair, mitochondrial health, metabolism, nicotinamide adenine dinucleotide (NAD+) levels, and immunological responses, become compromised. Urolithin A (UA) and Nico
Externí odkaz:
https://doaj.org/article/3e103a9947594f0087e35ad8f9ab37bb
Autor:
Alejandro Marmolejo-Garza, Laurent Chatre, Deborah L. Croteau, Alejandro Herron-Bedoya, Minh Danh Anh Luu, Benoit Bernay, Julien Pontin, Vilhelm A. Bohr, Erik Boddeke, Amalia M. Dolga
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106645- (2024)
Summary: Nicotinamide riboside (NR), a precursor of nicotinamide adenine dinucleotide (NAD+), has robust cognitive benefits and alleviates neuroinflammation in Alzheimer's Disease (AD) mouse models without decreasing beta-amyloid plaque pathology. Su
Externí odkaz:
https://doaj.org/article/4ee99df2197a4223b78289600027be29
Autor:
Edwin R. Miranda, Pallavi Varshney, Corey E. Mazo, James Shadiow, Andrew T. Ludlow, Jacob M. Haus
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103300- (2024)
Glyoxalase I (GLO1) is the primary enzyme for detoxification of the reactive dicarbonyl methylglyoxal (MG). Loss of GLO1 promotes accumulation of MG resulting in a recapitulation of diabetic phenotypes. We previously demonstrated attenuated GLO1 prot
Externí odkaz:
https://doaj.org/article/318951f6a16d406dbf8a1199a23cdddf
Autor:
Muhammad Saqlain Zaheer, Muhammad Rizwan, Nazish Aijaz, Akhtar Hameed, Kamran Ikram, Hafiz Haider Ali, Yasir Niaz, Hafiz M. Usman Aslam, Salim Manoharadas, Muhammad Waheed Riaz, Nadeem Ahmed, Rani Bibi, Muhammad Aamir Manzoor, Shamsur Rehman
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Water stress is a major danger to crop yield, hence new approaches to strengthen plant resilience must be developed. To lessen the negative effects of water stress on wheat plants, present study was arranged to investigate the rol
Externí odkaz:
https://doaj.org/article/cc1735b777414ef884342f67910e15e8
Akademický článek
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Autor:
Sandra Carrera-Juliá, Elena Obrador, Rafael López-Blanch, María Oriol-Caballo, Paz Moreno-Murciano, José M. Estrela
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
A recent pilot study in amyotrophic lateral sclerosis (ALS) patients analyzed the effect of a Mediterranean diet (MeDi) supplemented with nicotinamide riboside (NR, a NAD+ promoter), pterostilbene (PTER, a natural antioxidant) and/or coconut oil on a
Externí odkaz:
https://doaj.org/article/42d8156464c14488a2c5d3b9970a6439
Autor:
Giorgio Turconi, Farhan Alam, Tanima SenGupta, Sini Pirnes-Karhu, Soophie Olfat, Mark S. Schmidt, Kärt Mätlik, Ana Montaño-Rodriguez, Vladimir Heiskanen, Daniel Garton, Petteri T. Piepponen, Charles Brenner, Carina I. Holmberg, Hilde Nilsen, Eija Pirinen, Jaan-Olle Andressoo
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34355- (2024)
Parkinson's disease (PD) is associated with a reduction in 26/20S proteasome and mitochondrial function and depletion of dopamine. Activation of mitochondrial function with the NAD+ precursor nicotinamide riboside (NR) is a potential therapeutic for
Externí odkaz:
https://doaj.org/article/ac4f73d8f115461db81a3d5dd4a624da
Autor:
Yan Li, Chunjia Zhang, Zihan Li, Fan Bai, Yingli Jing, Han Ke, Shuangyue Zhang, Yitong Yan, Yan Yu
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 2, Pp 1291-1307 (2024)
Changes in intracellular nicotinamide adenine dinucleotide (NAD+) levels have been observed in various disease states. A decrease in NAD+ levels has been noted following spinal cord injury (SCI). Nicotinamide riboside (NR) serves as the precursor of
Externí odkaz:
https://doaj.org/article/908e806ced9a46b4ba14a9bfaa72b439
Autor:
Juan Carlos Rivera, Jorge Espinoza-Derout, Kamrul M. Hasan, Jocelyn Molina-Mancio, Jason Martínez, Candice J. Lao, Martin L. Lee, Desean L. Lee, Julian Wilson, Amiya P. Sinha-Hikim, Theodore C. Friedman
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionCigarettes containing nicotine (Nic) are a risk factor for the development of cardiovascular and metabolic diseases. We reported that Nic delivered via injections or e-cigarette vapor led to hepatic steatosis in mice fed with a high-fat d
Externí odkaz:
https://doaj.org/article/61f4887ed95b417f94add5bd981abdea