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pro vyhledávání: '"Ribonucleotide excision repair"'
Akademický článek
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Akademický článek
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Autor:
Rahel Polaczek, Peter Schürmann, Lisa-Marie Speith, Robert Geffers, Matthias Dürst, Peter Hillemanns, Tjoung-Won Park-Simon, Clemens Liebrich, Thilo Dörk
Publikováno v:
Journal of Ovarian Research, Vol 13, Iss 1, Pp 1-8 (2020)
Abstract Epithelial ovarian carcinoma (EOC) is a genetically heterogeneous disease that is partly driven by molecular defects in mismatch repair (MMR) or homology-directed DNA repair (HDR). Ribonuclease H2 serves to remove mis-incorporated ribonucleo
Externí odkaz:
https://doaj.org/article/2aa4987e0bc54061a0f9ddea526e100d
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Jan . 116(4), 1251-1260.
Externí odkaz:
https://www.jstor.org/stable/26580235
Autor:
Wanrooij, Paulina H., Engqvist, Martin K. M., Forslund, Josefin M. E., Navarrete, Clara, Nilsson, Anna Karin, Sedman, Juhan, Wanrooij, Sjoerd, Clausen, Anders R., Chabes, Andrei
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Nov . 114(47), 12466-12471.
Externí odkaz:
https://www.jstor.org/stable/26485595
Autor:
Schroeder, Jeremy W., Randall, Justin R., Hirst, William G., O’Donnell, Michael E., Simmons, Lyle A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Oct . 114(44), 11733-11738.
Externí odkaz:
https://www.jstor.org/stable/26488857
Autor:
John P. McDonald, Roger Woodgate, Harald Kranz, Karolina Makiela-Dzbenska, Wei Yang, Erin Walsh, Dominic R. Quiros, Alexandra Vaisman, Marlen Schmidt, Krystian Łazowski, Martin A M Reijns, Kristiniana C Moreno
Publikováno v:
Molecular Microbiology
The Escherichia coli dnaE gene encodes the α‐catalytic subunit (pol IIIα) of DNA polymerase III, the cell’s main replicase. Like all high‐fidelity DNA polymerases, pol III possesses stringent base and sugar discrimination. The latter is media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18288e845950c22833c6713336082a7
https://doi.org/10.1111/mmi.14779
https://doi.org/10.1111/mmi.14779
Publikováno v:
Genes to Cells
Ribonucleotides incorporated in the genome are a source of endogenous DNA damage and also serve as signals for repair. Although recent advances of ribonucleotide detection by sequencing, the balance between incorporation and repair of ribonucleotides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e97f428a22febe29a789ebdde5d9a9
https://doi.org/10.1111/gtc.12871
https://doi.org/10.1111/gtc.12871
Publikováno v:
Chemical Research in Toxicology. 32:926-934
Ribonucleotides can be incorporated into DNA through many different cellular processes, and abundant amounts of ribonucleotides are detected in genomic DNA. Embedded ribonucleotides lead to genomic instability through either spontaneous ribonucleotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6020cac1e87bab6b72bea88457c874
https://doi.org/10.1021/acs.chemrestox.9b00059
https://doi.org/10.1021/acs.chemrestox.9b00059
Autor:
Andrei Kuzminov, T.V. Pritha Rao
Publikováno v:
DNA Repair. 75:1-17
Thymine deprivation in thyA mutant E. coli causes thymineless death (TLD) and is the mode of action of popular antibacterial and anticancer drugs, yet the mechanisms of TLD are still unclear. TLD comprises three defined phases: resistance, rapid expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3019f3abd32f75e523e15bb1286f9c
https://doi.org/10.1016/j.dnarep.2019.01.002
https://doi.org/10.1016/j.dnarep.2019.01.002