Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ribhav Mishra"'
Autor:
Ankur Rakesh Dubey, Ribhav Mishra, Naveen Sundaria, Yuvraj Anandrao Jagtap, Prashant Kumar, Sumit Kinger, Akash Choudhary, Hem Chandra Jha, Amit Prasad, Ravi Kumar Gutti, Amit Mishra
Publikováno v:
Cellular Physiology and Biochemistry, Vol 56, Iss 5, Pp 530-545 (2022)
Externí odkaz:
https://doaj.org/article/39d3b77564964f31b1a401538a5006a5
Autor:
Deepak Chhangani, Fumito Endo, Ayeman Amanullah, Arun Upadhyay, Seiji Watanabe, Ribhav Mishra, Koji Yamanaka, Amit Mishra
Publikováno v:
Neurobiology of Disease, Vol 86, Iss , Pp 16-28 (2016)
Proteotoxicity of misfolded, disease-causing proteins is deeply implicated in the pathomechanisms for neurodegenerative diseases including copper-zinc superoxide dismutase (SOD1)-linked amyotrophic lateral sclerosis (ALS). However, the precise cellul
Externí odkaz:
https://doaj.org/article/0c01f85d4e0d4e88aab3d11364f22dc0
Autor:
Arun Upadhyay, Vibhuti Joshi, Ayeman Amanullah, Ribhav Mishra, Naina Arora, Amit Prasad, Amit Mishra
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Cells regularly synthesize new proteins to replace old or damaged proteins. Deposition of various aberrant proteins in specific brain regions leads to neurodegeneration and aging. The cellular protein quality control system develop various defense me
Externí odkaz:
https://doaj.org/article/1f962455b31440c2b5b1182535be8d12
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Cells regularly synthesize new proteins to replace old and abnormal proteins for normal cellular functions. Two significant protein quality control pathways inside the cellular milieu are ubiquitin proteasome system (UPS) and autophagy. Autophagy is
Externí odkaz:
https://doaj.org/article/7c04b6f557184c32a398122d762ee803
Autor:
Ankur Rakesh Dubey, Ribhav Mishra, Yuvraj Anandrao Jagtap, Sumit Kinger, Prashant Kumar, Rohan Dhiman, Somnath Ghosh, Sarika Singh, Amit Prasad, Nihar Ranjan Jana, Amit Mishra
Publikováno v:
Molecular Neurobiology. 60:2397-2412
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
CAG repeats RNA causes various fatal neurodegenerative diseases exemplified by Huntington’s disease (HD) and several spinocerebellar ataxias (SCAs). Although there are differences in the pathogenic mechanisms, these diseases share the common cause,
Publikováno v:
Molecular neurobiology. 58(12)
According to cellular demands, ribosomes synthesize and maintain the desired pool of proteins inside the cell. However, sometimes due to defects in ribosomal machinery and faulty mRNAs, these nascent polypeptides are constantly under threat to become
Autor:
Ribhav Mishra, Amy H. Lee, Inge S. Zuhorn, Pieter Vader, James W. Erickson, Ikuhiko Nakase, Frederik J. Verweij, Joshua L. Hood, Lisa Meyer, Alissa M. Weaver, Ryan P. McNamara, Tatsuo Kurihara, Nicole Noren Hooten, Shamba Gupta, Killian P. O’Brien, Jessica E Pullan, Y Peng Loh, Pooja Khatkar, Yi Zhao, Blanca V. Rodriguez, Yuriy Kim, Heather Branscome, Emma Purcell, Kathleen M Lennon, Maria Cowen, Nicole Comfort, Ryan Reshke, Martin Olivier, Crislyn D’Souza-Schorey, Simon Carding, Sarah F. Andres, Dennis A. Steindler, Johnny Akers, Shivani Sharma, Janos Zempleni, Dilorom Sass, Hannah M. McMillan, Moran Amit, Hameeda Sultana, Sarah Al Sharif, Laura Perin, Bridget Ratitong, Chukwumaobim D. Nwokwu, Tsuneya Ikezu, Jean C. Lee, Jordan Pavlic
Publikováno v:
Extracellular Vesicles and Circulating Nucleic Acids.
Progressing neurobiological strategies against proteostasis failure: Challenges in neurodegeneration
Autor:
Arun Upadhyay, Vibhuti Joshi, Ayeman Amanullah, Nihar Ranjan Jana, Ribhav Mishra, Amit Mishra
Publikováno v:
Progress in Neurobiology. 159:1-38
Proteins are ordered useful cellular entities, required for normal health and organism’s survival. The proteome is the absolute set of cellular expressed proteins, which regulates a wide range of physiological functions linked with all domains of l
Publikováno v:
Molecular Neurobiology. 55:1169-1182
Accumulation of misfolded or aberrant proteins in neuronal cells is linked with neurodegeneration and other pathologies. Which molecular mechanisms fail and cause inappropriate folding of proteins and what is their relationship to cellular toxicity i