Cytotoxic and immunomodulatory potential of a novel [2-(4-(2,5-dimethyl-1H-pyrrol-1-yl)-1H-pyrazol-3-yl)pyridine] in myeloid leukemia.

Autor: de Castro Alves CE; Post-Graduate Program in Basic and Applied Immunology, Institute of Biological Science, Federal University of Amazonas, Manaus 69077-000, AM, Brazil; Laboratory of Virology and Immunology, National Institute of Amazonian Research (INPA), Manaus 69067-375, AM, Brazil., Koidan G; Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanska 5, 02660 Kyiv 94, Ukraine., Hurieva AN; Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanska 5, 02660 Kyiv 94, Ukraine., de Freitas Gomes A; Laboratory of Virology and Immunology, National Institute of Amazonian Research (INPA), Manaus 69067-375, AM, Brazil; Post-Graduate Program in Hematology, The State University of Amazon, Foundation of Hematology and Hemotherapy of Amazonas, Manaus 69050-010, AM, Brazil., Costa de Oliveira R; Post-Graduate Program in Basic and Applied Immunology, Institute of Biological Science, Federal University of Amazonas, Manaus 69077-000, AM, Brazil; Post-Graduate Program in Hematology, The State University of Amazon, Foundation of Hematology and Hemotherapy of Amazonas, Manaus 69050-010, AM, Brazil., Guimarães Costa A; Post-Graduate Program in Basic and Applied Immunology, Institute of Biological Science, Federal University of Amazonas, Manaus 69077-000, AM, Brazil; Post-Graduate Program in Hematology, The State University of Amazon, Foundation of Hematology and Hemotherapy of Amazonas, Manaus 69050-010, AM, Brazil., Ribeiro Boechat AL; Post-Graduate Program in Basic and Applied Immunology, Institute of Biological Science, Federal University of Amazonas, Manaus 69077-000, AM, Brazil., Correa de Oliveira A; Laboratory of Virology and Immunology, National Institute of Amazonian Research (INPA), Manaus 69067-375, AM, Brazil., Zahorulko S; Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanska 5, 02660 Kyiv 94, Ukraine., Kostyuk A; Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanska 5, 02660 Kyiv 94, Ukraine., Soares Pontes G; Post-Graduate Program in Basic and Applied Immunology, Institute of Biological Science, Federal University of Amazonas, Manaus 69077-000, AM, Brazil; Laboratory of Virology and Immunology, National Institute of Amazonian Research (INPA), Manaus 69067-375, AM, Brazil; Post-Graduate Program in Hematology, The State University of Amazon, Foundation of Hematology and Hemotherapy of Amazonas, Manaus 69050-010, AM, Brazil. Electronic address: pontesbm1@gmail.com.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Jun; Vol. 162, pp. 114701. Date of Electronic Publication: 2023 Apr 14.