Antagonistic postsynaptic and presynaptic actions of cyclohexanol on neuromuscular synaptic transmission and function.

Autor: Dissanayake KN; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Pharmacology, Toxicology and Therapeutics, Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Margetiny F; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK., Whitmore CL; Toxicology, Trauma and Medicine Group, Dstl, Porton Down, Salisbury, UK., Chou RC; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK., Roesl C; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK., Patel V; Department of Pharmacology, Physiology and Neuroscience, Rutgers, State University of New Jersey, Newark, NJ, USA., McArdle JJ; Department of Pharmacology, Physiology and Neuroscience, Rutgers, State University of New Jersey, Newark, NJ, USA., Webster R; Weatherall Institute for Molecular Medicine, Radcliffe Infirmary, Oxford, UK., Beeson D; Weatherall Institute for Molecular Medicine, Radcliffe Infirmary, Oxford, UK., Tattersall JEH; Toxicology, Trauma and Medicine Group, Dstl, Porton Down, Salisbury, UK., Wyllie DJA; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India., Eddleston M; Pharmacology, Toxicology and Therapeutics, Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Ribchester RR; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.

Publikováno v: The Journal of physiology [J Physiol] 2021 Dec; Vol. 599 (24), pp. 5417-5449. Date of Electronic Publication: 2021 Nov 26.

Cite Share Publisher Correction: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD

Autor: White, Ma, Kim, E., Duffy, A., Adalbert, R., Phillips, Bu, Peters, Om, Stephenson, J., Yang, S., Francesca Massenzio, Lin, Z., Andrews, S., Segonds-Pichon, A., Metterville, J., Saksida, Lm, Mead, R., Ribchester, Rr, Barhomi, Y., Serre, T., Coleman, Mp, Fallon, Jr, Bussey, Tj, Brown RH Jr, Sreedharan, J.

Publikováno v: Alma Mater Studiorum Università di Bologna-IRIS

In the version of this article initially published, the footnote number 17 was missing from the author list for the two authors who contributed equally. Also, the authors have added a middle initial for author Justin R. Fallon and an acknowledgement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::398b339c3c2011e8a4576ba554aafca4
http://hdl.handle.net/11585/810069

Sarm1 Deletion, but Not WldS, Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy

Autor: Gilley, JN, Ribchester, RR, Coleman, MP

Publikováno v: Gilley, J, Ribchester, R R & Coleman, M P 2017, ' Sarm1 Deletion, but Not Wld S, Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy ', Cell Reports, vol. 21, no. 1, pp. 10-16 . https://doi.org/10.1016/j.celrep.2017.09.027
Cell Reports, Vol 21, Iss 1, Pp 10-16 (2017)

Studies with the WldS mutant mouse have shown that axon and synapse pathology in several models of neurodegenerative diseases are mechanistically related to injury-induced axon degeneration (Wallerian degeneration). Crucially, an absence of SARM1 del

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaafe10ade3944bc918111931acea884
https://www.pure.ed.ac.uk/ws/files/44817653/Gilley_et_al_accepted_manuscript.pdf

Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin.

Autor: Roesl C; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Evans ER; Public Health England, National Infection Service, Porton Down, Salisbury SP4 0JG, UK., Dissanayake KN; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Boczonadi V; Applied Neuromuscular Junction Facility, Bio-Imaging Unit, Biosciences Institute, University of Newcastle-upon-Tyne, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK., Jones RA; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Jordan GR; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Ledahawsky L; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Allen GCC; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Scott M; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Thomson A; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Wishart TM; The Roslin Institute, Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine, University of Edinburgh, Easter Bush, Edinburgh EH25 9RG, UK., Hughes DI; Spinal Cord Research Group, Institute of Neuroscience and Psychology, University of Glasgow, Glasgow G12 8QQ, UK., Mead RJ; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Glossop Road, Sheffield S10 2HQ, UK., Shone CC; Public Health England, National Infection Service, Porton Down, Salisbury SP4 0JG, UK., Slater CR; Applied Neuromuscular Junction Facility, Bio-Imaging Unit, Biosciences Institute, University of Newcastle-upon-Tyne, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK., Gillingwater TH; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Skehel PA; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK., Ribchester RR; Centre for Discovery Brain Sciences and the Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, George Square, Edinburgh EH8 9XD, UK.

Publikováno v: Biomolecules [Biomolecules] 2021 Oct 12; Vol. 11 (10). Date of Electronic Publication: 2021 Oct 12.

Synaptic withdrawal following nerve injury is influenced by postnatal maturity, muscle-specific properties, and the presence of underlying pathology in mice.

Autor: Mole AJ; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; The Euan MacDonald Centre for Motor Neurone Disease Research, Edinburgh, UK., Bell S; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; The Euan MacDonald Centre for Motor Neurone Disease Research, Edinburgh, UK., Thomson AK; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; The Euan MacDonald Centre for Motor Neurone Disease Research, Edinburgh, UK., Dissanayake KN; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; The Euan MacDonald Centre for Motor Neurone Disease Research, Edinburgh, UK., Ribchester RR; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; The Euan MacDonald Centre for Motor Neurone Disease Research, Edinburgh, UK., Murray LM; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; The Euan MacDonald Centre for Motor Neurone Disease Research, Edinburgh, UK.

Publikováno v: Journal of anatomy [J Anat] 2020 Aug; Vol. 237 (2), pp. 263-274. Date of Electronic Publication: 2020 Apr 20.