Human Endogenous Retrovirus Type W Envelope from Multiple Sclerosis Demyelinating Lesions Shows Unique Solubility and Antigenic Characteristics

Autor: Hervé Perron, Rianne P. Gorter, Christophe Quétard, Justine Pierquin, Sandra Amor, Benjamin Charvet, Jacques Portoukalian, Joanna Brunel, Branka Horvat

Publikováno v: Charvet, B, Pierquin, J, Brunel, J, Gorter, R, Quétard, C, Horvat, B, Amor, S, Portoukalian, J & Perron, H 2021, ' Human Endogenous Retrovirus Type W Envelope from Multiple Sclerosis Demyelinating Lesions Shows Unique Solubility and Antigenic Characteristics ', Virologica Sinica, vol. 36, no. 5, pp. 1006-1026 . https://doi.org/10.1007/s12250-021-00372-0
Virologica Sinica
Virologica Sinica, 36(5), 1006-1026

In multiple sclerosis (MS), human endogenous retrovirus W family (HERV-W) envelope protein, pHERV-W ENV, limits remyelination and induces microglia-mediated neurodegeneration. To better understand its role, we examined the soluble pHERV-W antigen fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403af3b17cbc32ad061ada236a37a711
https://research.vumc.nl/en/publications/9dff620d-3b71-4659-9dc8-f0eb09f28317

Rapidly progressive amyotrophic lateral sclerosis is associated with microglial reactivity and small heat shock protein expression in reactive astrocytes

Autor: Jasper J. Anink, Jeroen A.M. Beliën, Jodie Stephenson, J. C. de Jonge, Rianne P. Gorter, Wia Baron, Caroline Mijnsbergen, Erik Nutma, M. C. Jahreiβ, Eleonora Aronica, J M van Noort, Sandra Amor

Publikováno v: Neuropathology and applied neurobiology, 45(5), 459-475. Wiley-Blackwell
Neuropathology and Applied Neurobiology, 45(5), 459-475. Wiley-Blackwell
Neuropathology and Applied Neurobiology
Gorter, R P, Stephenson, J, Nutma, E, Anink, J, de Jonge, J C, Baron, W, Jahreiβ, M C, Belien, J A M, van Noort, J M, Mijnsbergen, C, Aronica, E & Amor, S 2019, ' Rapidly progressive amyotrophic lateral sclerosis is associated with microglial reactivity and small heat shock protein expression in reactive astrocytes ', Neuropathology and Applied Neurobiology, vol. 45, no. 5, pp. 459-475 . https://doi.org/10.1111/nan.12525
Neuropathology and Applied Neurobiology, 45(5), 459-475. WILEY-BLACKWELL

AIMS: Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease characterised by progressive loss of motor neurons, muscle weakness, spasticity, paralysis and death usually within 2-5 years of onset. Neuroinflammation is a hallmark o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0bc859e6c1c9a2c107cb494773d07b
https://research.rug.nl/en/publications/a523de00-84bd-4ba4-b937-533f88897371

Heat shock proteins are differentially expressed in brain and spinal cord

Autor: Erik Nutma, Sandra Amor, Rianne P. Gorter, Roy A. Quinlan, J M van Noort, M-C Jahrei, Wia Baron, P. van der Valk, J. C. de Jonge

Publikováno v: Gorter, R P, Nutma, E, Jahrei, M-C, de Jonge, J C, Quinlan, R A, van der Valk, P, van Noort, J M, Baron, W & Amor, S 2018, ' Heat shock proteins are differentially expressed in brain and spinal cord : implications for multiple sclerosis ', Clinical and Experimental Immunology, vol. 194, no. 2, pp. 137-152 . https://doi.org/10.1111/cei.13186
Clinical and Experimental Immunology, 194(2), 137-152. Wiley
Clinical and experimental immunology, 2018, Vol.194(2), pp.137-152 [Peer Reviewed Journal]
Clinical and Experimental Immunology, 194(2), 137-152. Wiley-Blackwell
Clinical and Experimental Immunology

AIMS: Multiple sclerosis (MS) is a chronic neurodegenerative disease characterised by demyelination, inflammation and neurodegeneration throughout the central nervous system. Although spinal cord pathology is an important factor contributing to disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825dd92b4cb629ecca73ec3a89242db5
https://doi.org/10.1111/cei.13186

A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis.

Autor: Nutma, Erik, Stephenson, Jodie A, Gorter, Rianne P, Bruin, Joy de, Boucherie, Deirdre M, Donat, Cornelius K, Breur, Marjolein, van der Valk, Paul, Matthews, Paul M, Owen, David R, Amor, Sandra, de Bruin, Joy

Publikováno v: Brain: A Journal of Neurology; Nov2019, Vol. 142 Issue 11, p3440-3455, 16p

Experimental Models of Infection, Inflammation and Injury

Autor: David Montrose

Experimental Models of Infection, Inflammation and Injury, Volume 168 provides step-by-step protocols for scientific researchers to effectively utilize experimental model systems. Chapters in this new release include Induction and Evaluation of Murin