Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rianne M. Jongman"'
Autor:
Sophie F. Ellermann, Rianne M. Jongman, Matthijs Luxen, Timara Kuiper, Josee Plantinga, Jill Moser, Thomas W. L. Scheeren, Gregor Theilmeier, Grietje Molema, Matijs Van Meurs
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Major surgery induces systemic inflammation leading to pro-inflammatory activation of endothelial cells. Endothelial inflammation is one of the drivers of postoperative organ damage, including acute kidney injury Tumour Necrosis Factor alpha (TNF-α)
Externí odkaz:
https://doaj.org/article/cf25c4bc3adc4a79a97601512bf31bd1
Autor:
Peter J. Zwiers, Jacqueline P. F. E. Lucas, Rianne M. Jongman, Matijs van Meurs, Eliane R. Popa, Grietje Molema
Publikováno v:
Cells, Vol 12, Iss 14, p 1850 (2023)
Endothelial cells (ECs) in the microvasculature in organs are active participants in the pathophysiology of sepsis. Tyrosine protein kinase receptor Tie2 (Tek; Tunica interna Endothelial cell Kinase) is thought to play a role in their inflammatory re
Externí odkaz:
https://doaj.org/article/11b6b9db5f9f4453bbffe80e08ab5adc
Autor:
Peter J. Zwiers, Rianne M. Jongman, Timara Kuiper, Jill Moser, Radu V. Stan, Joachim R. Göthert, Matijs van Meurs, Eliane R. Popa, Grietje Molema
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Tyrosine-protein kinase receptor Tie2, also known as Tunica interna Endothelial cell Kinase or TEK plays a prominent role in endothelial responses to angiogenic and inflammatory stimuli. Here we generated a novel inducible Tie2 knockout mouse model,
Externí odkaz:
https://doaj.org/article/87343e3da24d4f7fb9bde788a5e7c178
Autor:
Rens Zonneveld, Rianne M Jongman, Amadu Juliana, Grietje Molema, Matijs van Meurs, Frans B Plötz
Publikováno v:
BMJ Paediatrics Open, Vol 2, Iss 1 (2018)
Background Early onset sepsis (EOS) is defined as onset of sepsis within 72 hours after birth. Leucocyte-endothelial interactions play a pivotal part in EOS pathophysiology. Endothelial cell adhesion molecules (CAMs) orchestrate these interactions an
Externí odkaz:
https://doaj.org/article/27dbcfce528d4b91a4c1d6fd7d13c0f3
Autor:
Ranran Li, Piotr S Kowalski, Henriëtte W M Morselt, Ilona Schepel, Rianne M Jongman, Adnan Aslan, Marcel H J Ruiters, Jan G Zijlstra, Grietje Molema, Matijs van Meurs, Jan A A M Kamps
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196976 (2018)
Microvascular endothelial cells play a pivotal role in the pathogenesis of sepsis-induced inflammatory responses and multiple organ failure. Therefore, they represent an important target for pharmacological intervention in the treatment of sepsis. Gl
Externí odkaz:
https://doaj.org/article/2d3f90545f42472cbc9adfa8c158d4fe
Autor:
Rens Zonneveld, Rianne M. Jongman, Niek B Achten, Matijs van Meurs, Amadu Juliana, Anita Bultman, Jan Wilschut, Frans B. Plötz
Publikováno v:
Pediatric pulmonology, 56(12), 3908-3915. Wiley-Liss Inc.
Pediatric pulmonology, 56(12), 3908-3915. Wiley
Pediatric pulmonology, 56(12), 3908-3915. Wiley
BACKGROUND: Evidence shows that activation of pulmonary vascular endothelium and neutrophils are involved in the pathophysiology of acute bronchiolitis. We hypothesized that levels of markers of endothelial activation and leukocyte counts are associa
Autor:
Peter Heeringa, Matijs van Meurs, Rianne M. Jongman, Michel Struys, Wayel H. Abdulahad, Dirk J. Bosch
Publikováno v:
British Journal of Anaesthesia, 125(3), 267-274. ELSEVIER SCI LTD
Background: Anaesthetic agents are likely to alter circulating cytokine concentrations. Because preceding studies have not been able to exclude the contribution of surgical trauma, perioperative stress, or both to circulating cytokine concentrations,
Autor:
Peter J. Zwiers, Nicolette C. A. Huijkman, Matijs van Meurs, Bart van de Sluis, Jill Moser, Jan G. Zijlstra, Daphne Dekker, Henk E. Moorlag, Rianne M. Jongman, Eliane R. Popa, Grietje Molema, Marleen van der Laan
Publikováno v:
Shock (Augusta, Ga.)
Shock, 51(6), 757-769. LIPPINCOTT WILLIAMS & WILKINS
Shock, 51(6), 757-769. LIPPINCOTT WILLIAMS & WILKINS
Supplemental Digital Content is available in the text
Tyrosine kinase receptor (Tie2) is mainly expressed by endothelial cells. In animal models mimicking critical illness, Tie2 levels in organs are temporarily reduced. Functional consequences o
Tyrosine kinase receptor (Tie2) is mainly expressed by endothelial cells. In animal models mimicking critical illness, Tie2 levels in organs are temporarily reduced. Functional consequences o
Autor:
Peter J. Zwiers, Rianne M. Jongman, Timara Kuiper, Jill Moser, Radu V. Stan, Joachim R. Göthert, Matijs van Meurs, Eliane R. Popa, Grietje Molema
Publikováno v:
PLoS ONE, 17(6):e0268986. PUBLIC LIBRARY SCIENCE
Tyrosine-protein kinase receptor Tie2, also known as Tunica interna Endothelial cell Kinase or TEK plays a prominent role in endothelial responses to angiogenic and inflammatory stimuli. Here we generated a novel inducible Tie2 knockout mouse model,
Publikováno v:
Journal of tropical pediatrics, 67(1):fmaa091. Oxford University Press
Journal of Tropical Pediatrics, 67(1):fmaa091. Oxford Univ. Press, New York
Journal of Tropical Pediatrics, 67(1):fmaa091. Oxford Univ. Press, New York
Background Systemic serum levels of markers of endothelial activation are associated with infection. We hypothesize that levels of markers of endothelial activation are associated with the presence of a positive blood culture as a manifestation of a