Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Rianne C Scholman"'
Autor:
Yvonne Vercoulen, Felicitas Bellutti Enders, Jenny Meerding, Maud Plantinga, Elisabeth F Elst, Hemlata Varsani, Christa van Schieveen, Mette H Bakker, Mark Klein, Rianne C Scholman, Wim Spliet, Valeria Ricotti, Hans J P M Koenen, Roel A de Weger, Lucy R Wedderburn, Annet van Royen-Kerkhof, Berent J Prakken
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105353 (2014)
Juvenile dermatomyositis (JDM) is an immune-mediated inflammatory disease affecting the microvasculature of skin and muscle. CD4+ CD25+ FOXP3+ regulatory T cells (Tregs) are key regulators of immune homeostasis. A role for Tregs in JDM pathogenesis h
Externí odkaz:
https://doaj.org/article/3296525a23284cd694bfd5b6d58efaec
Autor:
Lucas W. Picavet, Ellen C. N. van Vroonhoven, Rianne C. Scholman, Yesper T. H. Smits, Rupa Banerjee, Sjanna B. Besteman, Mattheus C. Viveen, Michiel M. van der Vlist, Marvin E. Tanenbaum, Robert J. Lebbink, Sebastiaan J. Vastert, Jorg van Loosdregt
Publikováno v:
Viruses, Vol 16, Iss 5, p 778 (2024)
Respiratory syncytial virus (RSV) is the most prevalent cause of acute lower respiratory infection in young children. Currently, the first RSV vaccines are approved by the FDA. Recently, N6-methyladenosine (m6A) RNA methylation has been implicated in
Externí odkaz:
https://doaj.org/article/d60fff36f6e3484aa6012a3b7d0cdb64
Autor:
Ellen C. N. van Vroonhoven, Lucas W. Picavet, Rianne C. Scholman, Noortje A. M. van den Dungen, Michal Mokry, Anouk Evers, Robert J. Lebbink, Jorg J. A. Calis, Sebastiaan J. Vastert, Jorg van Loosdregt
Publikováno v:
Biology, Vol 12, Iss 7, p 1004 (2023)
T cell activation is a highly regulated process, modulated via the expression of various immune regulatory proteins including cytokines, surface receptors and co-stimulatory proteins. N6-methyladenosine (m6A) is an RNA modification that can directly
Externí odkaz:
https://doaj.org/article/e018e45d2b0a4df48705f4e586c2bf9d
Autor:
Judith Wienke, Laura Brouwers, Leone M. van der Burg, Michal Mokry, Rianne C. Scholman, Peter G.J. Nikkels, Bas B. van Rijn, Femke van Wijk
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
Tregs are crucial for maintaining maternal immunotolerance against the semiallogeneic fetus. We investigated the elusive transcriptional profile and functional adaptation of human uterine Tregs (uTregs) during pregnancy. Uterine biopsies, from placen
Externí odkaz:
https://doaj.org/article/d19c326c2da34058a67b7eb08401cc20
Autor:
Janneke G C Peeters, Arjan Boltjes, Rianne C Scholman, Stephin J Vervoort, Paul J Coffer, Michal Mokry, Sebastiaan J Vastert, Femke van Wijk, Jorg van Loosdregt
Publikováno v:
Rheumatology.
Objectives How the local inflammatory environment regulates epigenetic changes in the context of inflammatory arthritis remains unclear. Here we assessed the transcriptional and active enhancer profile of monocytes derived from the inflamed joints of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcd0a262e821b0032473563c086139ad
https://doi.org/10.1093/rheumatology/kead001
https://doi.org/10.1093/rheumatology/kead001
Autor:
Ceri A. Roberts, Femke van Wijk, Veerle Fleskens, Sytze de Roock, Mark Wekking, Sebastiaan J. Vastert, Marthe Knijff, Gerdien Mijnheer, Weiyang Tao, Janneke G. C. Peeters, Leonie S. Taams, Lisanne Lutter, Michal Mokry, Rianne C. Scholman, Marlot van der Wal, Jorg van Loosdregt, Stephin J. Vervoort, Aridaman Pandit, Alessandra Petrelli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Treg cells are critical regulators of immune homeostasis, and environment-driven Treg cell differentiation into effector (e)Treg cells is crucial for optimal functioning. However, human Treg cell programming in inflammation is unclear. Here, we combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7f0f87cba9d9bb49145a7d186ed6c2
https://doaj.org/article/0a5628b633d646d0b5877f5920381df7
https://doaj.org/article/0a5628b633d646d0b5877f5920381df7
Autor:
Marthe Knijff, Marlot van der Wal, Janneke G. C. Peeters, Leonie S. Taams, Jorg van Loosdregt, Sytze de Roock, Mark Wekking, Femke van Wijk, Rianne C. Scholman, Aridaman Pandit, Michal Mokry, Weiyang Tao, Gerdien Mijnheer, Ceri A. Roberts, Stephin J. Vervoort, Alessandra Petrelli, Lisanne Lutter, Sebastiaan J. Vastert, Veerle Fleskens
Treg are critical regulators of immune homeostasis, and increasing evidence demonstrates that environment-driven Treg differentiation into effector (e)Treg is crucial for optimal functioning. However, human Treg programming under inflammatory conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad188c894f2ff2dde81ac509426a615
https://doi.org/10.1101/2020.09.30.319962
https://doi.org/10.1101/2020.09.30.319962
Autor:
Laura Brouwers, Judith Wienke, Bas B. van Rijn, Peter G. J. Nikkels, Michal Mokry, Leone M. van der Burg, Femke van Wijk, Rianne C. Scholman
Publikováno v:
JCI Insight
JCI insight, 5(18). The American Society for Clinical Investigation
JCI Insight, Vol 5, Iss 18 (2020)
JCI insight, 5(18). The American Society for Clinical Investigation
JCI Insight, Vol 5, Iss 18 (2020)
Tregs are crucial for maintaining maternal immunotolerance against the semiallogeneic fetus. We investigated the elusive transcriptional profile and functional adaptation of human uterine Tregs (uTregs) during pregnancy. Uterine biopsies, from placen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b73153f06b7a2d1db65edbc455d6d2
https://pubmed.ncbi.nlm.nih.gov/32809975
https://pubmed.ncbi.nlm.nih.gov/32809975
Autor:
Leone M. van der Burg, Rianne C. Scholman, Bas B. van Rijn, Peter G. J. Nikkels, Judith Wienke, Femke van Wijk, Michal Mokry, Laura Brouwers
ObjectivesRegulatory T cells (Tregs) are crucial for maintaining immune tolerance against the semi-allogeneic fetus during pregnancy. Since their functional profile at the human maternal-fetal interface is still elusive, we investigated the transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08df497876bb378230fd27ef37adc54b
Autor:
Nico M Wulffraat, Trang T. Duong, Joost F Swart, SJ Vastert, Jedidja Baaij, Rae S. M. Yeung, Sytze de Roock, Rianne C. Scholman
Publikováno v:
Poster Presentations.
Background: Heterogeneity in response to biological medication is a major challenge in the management of Juvenile Idiopathic Arthritis (JIA) (1). Biomarkers such as cytokines or whole blood RNA expression profiles that predict therapy efficacy prior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02f8fafbb9104e10eee9c1cb160df6b8
https://doi.org/10.1136/annrheumdis-2019-eular.6737
https://doi.org/10.1136/annrheumdis-2019-eular.6737