Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Riad Abès"'
Autor:
Nicolas Poirier, Irène Baccelli, Lyssia Belarif, Riad Abès, Géraldine Teppaz, Caroline Mary, Sonia Poli, Claudia Fromond, Isabelle Girault, Sabrina Pengam, Emilienne Soma, Fanny De Sa, Jean-Pascal Conduzorgues, Cécile Braudeau, Regis Josien, Bram Volckaert, Dominique Costantini, Frédérique Corallo
Publikováno v:
The Journal of Immunology. 210:753-763
OSE-127 is a humanized mAb targeting the IL-7Rα-chain (CD127), under development for inflammatory and autoimmune disease treatment. It is a strict antagonist of the IL-7R pathway, is not internalized by target cells, and is noncytotoxic. In this wor
Autor:
Jean-Luc Teillaud, Riad Abès
Publikováno v:
Pharmaceuticals, Vol 3, Iss 1, Pp 146-157 (2010)
Human IgG has only one conserved glycosylation site located in the Cγ2 domain of the Fc region that accounts for the presence of two sugar moieties per IgG. These IgG sugar cores play a critical role in a number of IgG effector functions. In the pre
Externí odkaz:
https://doaj.org/article/ba6de702c1f5425ea44ea1c55b973c38
Publikováno v:
Blood. 116:926-934
The anti-CD20 monoclonal antibody (mAb) rituximab has been used successfully for lymphoma therapy for more than 10 years. Although several direct mechanisms by which anti-CD20 mAbs act have been characterized in vitro, their specific role in clinical
Publikováno v:
médecine/sciences. 25:1011-1019
L’utilisation therapeutique des anticorps monoclonaux connait une croissance exponentielle. Nos connaissances sur leur structure, en particulier celle des IgG1 largement utilisees en therapeutique, se sont considerablement accrues. Cependant, de no
Autor:
Riad Abès, Jean-Luc Teillaud
Publikováno v:
Cancer metastasis reviews. 30(1)
The surveillance of tumors by the immune system of cancer patients and its impact on disease progression and patient survival have been largely documented over the last years. In parallel, the use of therapeutic monoclonal antibodies (mAbs) in oncolo
Publikováno v:
Expert review of clinical immunology. 5(6)
Membrane Fcgamma receptors (FcgammaRs) can act either as potent activators of effector cell functions or as inhibitors of receptor-mediated cell activation following engagement by IgG antibodies bound to their target molecules. The remarkable ability
Autor:
Jean-Luc Teillaud, Mariana Rodriguez-Zubieta, Marina Colombo, Gabriela Andrea Pizzurro, Riad Abès, Maria Marcela Barrio, Charlotte Boix, José Mordoh, María Paula Roberti, Emmanuelle Gélizé
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40311 (2012)
PLoS ONE
PLoS ONE
Dendritic cells (DC) can achieve cross-presentation of naturally-occurring tumor-associated antigens after phagocytosis and processing of dying tumor cells. They have been used in different clinical settings to vaccinate cancer patients. We have prev
Publikováno v:
Scopus-Elsevier
Autor:
Deligne, Claire, Teillaud, Jean-Luc
Publikováno v:
Médecine Sciences; jan2013, Vol. 29 Issue 1, p57-63, 7p
Autor:
Riad Abes, Agnès Bernet, Jean-Guy Delcros, Stéphane Depil, Patrick Mehlen, David Goldschneider, David Neves, Benjamen Ducarouge, John Blachier, Benjamin Gibert
Publikováno v:
Cancer Research. 75:2921-2921
Background: Some receptors are active in the absence of ligand and actively trigger cell death through apoptosis. These receptors are called “dependence receptors” (DRs) as their expression at the cell surface renders cells critically dependent f