Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ria, de Haas"'
Autor:
Julien Beyrath, Jan A.M. Smeitink, Charlotte A. Hoogstraten, G. Herma Renkema, Ria de Haas, Tom J.J. Schirris, Sanne J. C. M. Frambach, Peter H.G.M. Willems, Richard A. Notebaart, Frans G. M. Russel, Sergio Rossell, Martijn A. Huynen
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease 1867 (2021) 4
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1867(4)
Biochimica et biophysica acta. Molecular basis of disease, 1867, 4
Biochimica et biophysica acta. Molecular basis of disease, 1867
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1867(4)
Biochimica et biophysica acta. Molecular basis of disease, 1867, 4
Biochimica et biophysica acta. Molecular basis of disease, 1867
Contains fulltext : 229007.pdf (Publisher’s version ) (Open Access) The majority of cellular energy is produced by the mitochondrial oxidative phosphorylation (OXPHOS) system. Failure of the first OXPHOS enzyme complex, NADH:ubiquinone oxidoreducta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f94fa7cc37c361225d6438bfd4d3973
https://research.wur.nl/en/publications/stimulation-of-cholesterol-biosynthesis-in-mitochondrial-complex-
https://research.wur.nl/en/publications/stimulation-of-cholesterol-biosynthesis-in-mitochondrial-complex-
Autor:
Merel J W, Adjobo-Hermans, Ria, de Haas, Peter H G M, Willems, Aleksandra, Wojtala, Sjenet E, van Emst-de Vries, Jori A, Wagenaars, Mariel, van den Brand, Richard J, Rodenburg, Jan A M, Smeitink, Leo G, Nijtmans, Leonid A, Sazanov, Mariusz R, Wieckowski, Werner J H, Koopman
Publikováno v:
Biochimica et biophysica acta. Bioenergetics. 1861(8)
Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly understood pediatric disorder featuring brain-specific anomalies and early death. T
Autor:
Gerard A. Rongen, Sanne J. C. M. Frambach, Jan A.M. Smeitink, Tom J.J. Schirris, Ria de Haas, Frans G. M. Russel
Publikováno v:
Pharmacological Reviews, 72, 1, pp. 152-190
Pharmacological Reviews, 72, 152-190
Pharmacological Reviews, 72, 152-190
Contains fulltext : 218652.pdf (Publisher’s version ) (Closed access) Atherosclerosis is a leading cause of cardiovascular disease worldwide, and hypercholesterolemia is a major risk factor. Preventive treatments mainly focus on the effective reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a56765d93c650ed2e2c317311a7a86d
https://hdl.handle.net/2066/218652
https://hdl.handle.net/2066/218652
Autor:
Melissa A.E. van de Wal, Sanne J. C. M. Frambach, Frans G. M. Russel, Jan A.M. Smeitink, Tom J.J. Schirris, Ria de Haas, Petra H.H. van den Broek
Publikováno v:
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1866
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1866, 6
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1866, 6
Mitochondrial complex I (CI), the first multiprotein enzyme complex of the OXPHOS system, executes a major role in cellular ATP generation. Consequently, dysfunction of this complex has been linked to inherited metabolic disorders, including Leigh di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5bf0a85cfb9515d9b44cde072e06879
http://hdl.handle.net/2066/218559
http://hdl.handle.net/2066/218559
Autor:
Leo G.J. Nijtmans, Mariël A.M. van den Brand, Jori A. L. Wagenaars, Leonid A. Sazanov, Werner J.H. Koopman, Jan A.M. Smeitink, Merel J. W. Adjobo-Hermans, Sjenet E. van Emst-de Vries, Mariusz R. Wieckowski, Richard J. Rodenburg, Peter H.G.M. Willems, Aleksandra Wojtala, Ria de Haas
Publikováno v:
Biochimica et Biophysica Acta. Bioenergetics, 1861
Biochimica et Biophysica Acta. Bioenergetics, 1861, 8
Biochimica et Biophysica Acta. Bioenergetics, 1861, 8
Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly understood pediatric disorder featuring brain-specific anomalies and early death. T
Autor:
Eneda Pjetri, Ria de Haas, Simone de Jong, Cigdem Gelegen, Hugo Oppelaar, Linda A W Verhagen, Marinus J C Eijkemans, Roger A Adan, Berend Olivier, Martien J Kas
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50453 (2012)
Animal studies are very useful in detection of early disease indicators and in unravelling the pathophysiological processes underlying core psychiatric disorder phenotypes. Early indicators are critical for preventive and efficient treatment of progr
Externí odkaz:
https://doaj.org/article/fc7b1e65ba72473bb7f66435da962330
Autor:
Lisa C M W Heltzel, Jan A.M. Smeitink, Ria de Haas, Frans G. M. Russel, Petra H.H. van den Broek, Michel M.M. Verheij, Ken Nakamura, Hilbert Steenbreker, Adam L. Orr, Denise Tax
Publikováno v:
Brain Communications, 1, fcz016
Brain Communications
Brain Communications, 1, 1, pp. fcz016
Brain Communications
Brain Communications, 1, 1, pp. fcz016
The PTEN-induced putative kinase 1 knockout rat (Pink1−/−) is marketed as an established model for Parkinson’s disease, characterized by development of motor deficits and progressive degeneration of half the dopaminergic neurons in the substant
Publikováno v:
Behavioural Brain Research, 296, pp. 191-8
Behavioural Brain Research, 296, 191-8
Behavioural Brain Research, 296, 191-8
Contains fulltext : 170843.pdf (Publisher’s version ) (Closed access) Leigh disease (LD) is one of the clinical phenotypes of mitochondrial OXPHOS disorders and also known as sub-acute necrotizing encephalomyelopathy. The disease has an incidence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a66fe38dca3f24c13939308020d4f80
https://hdl.handle.net/2066/170843
https://hdl.handle.net/2066/170843
Publikováno v:
European Neuropsychopharmacology. 22:657-663
Obsessive-compulsive disorder (OCD) is a chronic and complex psychiatric disorder with a lifetime prevalence of 2-3%. Recent work has shown that OCD rituals were not only characterized by a high rate of repetition but also by an increased behavioral
Autor:
Martien J H Kas, Roger A.H. Adan, Eneda Pjetri, Marinus J.C. Eijkemans, Berend Olivier, Linda A. W. Verhagen, H. Oppelaar, Cigdem Gelegen, Simone de Jong, Ria de Haas
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e50453 (2012)
PLoS ONE, Vol 7, Iss 11, p e50453 (2012)
Animal studies are very useful in detection of early disease indicators and in unravelling the pathophysiological processes underlying core psychiatric disorder phenotypes. Early indicators are critical for preventive and efficient treatment of progr