Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ri-Fang Yang"'
Autor:
Hong-xia Chen, Zeng-liang Jin, Li-ming Zhang, Rui Xue, Xiao-dan Xu, Nan Zhao, Zhi-kun Qiu, Xian-wang Wang, You-zhi Zhang, Ri-fang Yang, Yun-feng Li
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83271 (2013)
It has been suggested that drugs combining activities of selective serotonin reuptake inhibitor and 5-HT1A receptor agonist may form a novel strategy for higher therapeutic efficacy of antidepressant. The present study aimed to examine the pharmacolo
Externí odkaz:
https://doaj.org/article/83d7baa9c5bc4f9f9af93f40daf39bfc
Autor:
Xiao-Xu Hu, Ri-Fang Yang, You-Zhi Zhang, Yun-Feng Li, Nan Zhao, Yu-Lu Wang, Li-Ming Zhang, Yu-Hua Ran, Xiao-Yun Wang, Yan-Qin Liu
Publikováno v:
British Journal of Pharmacology. 174:769-780
The purpose of the present study was to investigate the pharmacology of hypidone hydrochloride (YL-0919), a novel selective serotonin reuptake inhibitor (SSRI) and 5-hydroxytryptamine (5-HT)1A receptor agonist with high affinity for serotonin transpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c649a6051f523e2e714d84c2a8dcd47
https://doi.org/10.1111/bph.13675
https://doi.org/10.1111/bph.13675
Publikováno v:
Neuropharmacology. 113:567-575
The present study aimed to examine the molecular and cellular mechanisms underlying the antidepressant-like effect of YL-IPA08, a novel TSPO ligand designed and synthesized at our institute. We firstly used the chronic unpredictable stress (CUS) proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7cddc63f36508535c797ccf15dbdb8d
https://doi.org/10.1016/j.neuropharm.2016.11.004
https://doi.org/10.1016/j.neuropharm.2016.11.004
Autor:
Hong-Xia Chen, Li Yunfeng, Nan Zhao, Li-Ming Zhang, Xiao-fei Chen, Rui Xue, Zhi-Kun Qiu, You-Zhi Zhang, Ri-Fang Yang
Publikováno v:
Journal of Psychopharmacology. 30:474-481
Cholesterol import into mitochondria through the translocator protein (18 KDa) (TSPO) is the starting point and an important rate-limiting step in neurosteroidogenesis. For this reason TSPO has received increased attention in the pathophysiology of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560d372e15327f3448f2932dd349d2d3
https://doi.org/10.1177/0269881115625115
https://doi.org/10.1177/0269881115625115
Autor:
Nan Zhao, Zeng-liang Jin, Yun-Feng Li, Hong-Xia Chen, Zhi-Kun Qiu, Rui Xue, Wen-Zhi Guo, Li-Ming Zhang, You-Zhi Zhang, Ri-Fang Yang
Publikováno v:
Neuropharmacology. 81:116-125
It has been demonstrated that the translocator protein (18 kDa) (TSPO) plays an important role in stress-response and stress-related disorders, such as anxiety and depression, by affecting the production of neurosteroids, supporting the potential use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3250967fb9cf4a5048ac97523011ca7e
https://doi.org/10.1016/j.neuropharm.2013.09.016
https://doi.org/10.1016/j.neuropharm.2013.09.016
Publikováno v:
European Journal of Pharmacology. 720:212-217
Increasing evidence suggests that the mesolimbic dopamine system plays a critical role in opioid addiction. However, there is currently no standard drug treatment for opioid addiction. Growing preclinical evidence indicates that the dopamine D(3) rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a204ea347c35bb3987052e5ce5e8256
https://doi.org/10.1016/j.ejphar.2013.10.026
https://doi.org/10.1016/j.ejphar.2013.10.026
Autor:
Rui Bin Su, Rui Song, Xiao Qing Peng, Eliot L. Gardner, Hai Ying Zhang, Zheng-Xiong Xi, Jin Li, Ri Fang Yang
Publikováno v:
Neuropharmacology. 72:82-87
The dopamine (DA) D3 receptor (D3R) has received much attention in medication development for treatment of addiction. However, the functional role of the D3R in drug reward and addiction has been a matter of debate. We recently reported that D3 recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f30f89817f094ac5bf1aa37b3ca70eb3
https://doi.org/10.1016/j.neuropharm.2013.04.042
https://doi.org/10.1016/j.neuropharm.2013.04.042
Autor:
Li-Ming, Zhang, Xiao-Yun, Wang, Nan, Zhao, Yu-Lu, Wang, Xiao-Xu, Hu, Yu-Hua, Ran, Yan-Qin, Liu, You-Zhi, Zhang, Ri-Fang, Yang, Yun-Feng, Li
Publikováno v:
British journal of pharmacology. 174(9)
Our previous studies revealed that hypidone hydrochloride (YL-0919), which acts as a selective 5-HT (serotonin) reuptake inhibitor (SSRI) and displays partial 5-HTWe first investigated the target profile of YL-0919 using [Data from the present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab1198299522385d8820f88591be2bc7
https://pubmed.ncbi.nlm.nih.gov/27882537
https://pubmed.ncbi.nlm.nih.gov/27882537
Autor:
Xiao-Rui Cheng, Liu-Hong Yun, Yongxiang Zhang, Ri-Fang Yang, Jun-Ping Cheng, Wenxia Zhou, Yu Zhou, Jin-Wu Zhou
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1408-1414
(2)-Epigallocatechin-3-gallate (EGCG) is a major polyphenolic component of green tea. A number of studies have demonstrated EGCG has the possibility for delaying the onset or retarding the progression of Alzheimer’s disease (AD) and indicated EGCG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1cc7cf11854176c8424e767dd943c18
https://doi.org/10.1016/j.bmcl.2011.12.034
https://doi.org/10.1016/j.bmcl.2011.12.034
Autor:
Ri-Fang Yang, Rui Song, Rui-Bin Su, Xia Li, Xiao-Qing Peng, József Gaál, Ning Wu, Eliot L. Gardner, Jin Li, Zheng-Xiong Xi
Publikováno v:
Addiction Biology. 17:259-273
The dopamine (DA) D3 receptor is posited to be importantly involved in drug reward and addiction, and D3 receptor antagonists have shown extraordinary promise as potential anti-addiction pharmacotherapeutic agents in animal models of drug addiction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92b83e3ad4602cc6e7f59d43bef377ee
https://doi.org/10.1111/j.1369-1600.2011.00317.x
https://doi.org/10.1111/j.1369-1600.2011.00317.x