Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rhys A. Lippa"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1617-1626 (2020)
Integrin inhibitors based on the tripeptide sequence Arg–Gly–Asp (RGD) are potential therapeutics for the treatment of idiopathic pulmonary fibrosis (IPF). Herein, we describe an expeditious three-step synthetic sequence of Horner–Wadsworth–E
Externí odkaz:
https://doaj.org/article/159af02f23c14708a242e80642411380
Publikováno v:
The Journal of Organic Chemistry. 86:3583-3604
Substituted arylethylamines represent a key structural motif in natural, pharmaceutical, and agrochemical compounds. Access to such scaffolds has been the subject of long-standing synthetic interest. Herein, we report the synthesis of such scaffolds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f65c37df9a1d4c248d83e22c14874c
https://doi.org/10.1021/acs.joc.0c02958
https://doi.org/10.1021/acs.joc.0c02958
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1617-1626 (2020)
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1617-1626 (2020)
Integrin inhibitors based on the tripeptide sequence Arg–Gly–Asp (RGD) are potential therapeutics for the treatment of idiopathic pulmonary fibrosis (IPF). Herein, we describe an expeditious three-step synthetic sequence of Horner–Wadsworth–E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15fa7f75f652a6cd6810c1d6f2a96b2
http://europepmc.org/articles/PMC7356399
http://europepmc.org/articles/PMC7356399
Publikováno v:
The Journal of organic chemistry. 86(4)
Substituted arylethylamines represent a key structural motif in natural, pharmaceutical, and agrochemical compounds. Access to such scaffolds has been the subject of long-standing synthetic interest. Herein, we report the synthesis of such scaffolds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba298a0f1a53b0a16ebd68ee0a65b108
https://pubmed.ncbi.nlm.nih.gov/33513016
https://pubmed.ncbi.nlm.nih.gov/33513016
Autor:
Rhys A, Lippa, John, Barrett, Sandeep, Pal, James E, Rowedder, John A, Murphy, Tim N, Barrett
Publikováno v:
European journal of medicinal chemistry. 208
Integrins α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c4c9eacaeb6cf1dd893d1ba3a8e3097
https://pubmed.ncbi.nlm.nih.gov/32865176
https://pubmed.ncbi.nlm.nih.gov/32865176
Publikováno v:
European Journal of Medicinal Chemistry. 208:112719
Integrins αvβ5 and αvβ3 are closely related, proangiogenic members of the wider RGD-binding integrin family. Due to their high sequence homology, the development of αvβ5-selective compounds has remained elusive to synthetic and medicinal chemis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d045aaf9d0a7f6858bdcbcb33914ba1c
https://doi.org/10.1016/j.ejmech.2020.112719
https://doi.org/10.1016/j.ejmech.2020.112719