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Performance of a multi-biomarker panel for prediction of cardiovascular event in patients with chronic kidney disease.

Autor: Mohebi R; Massachusetts General Hospital, Boston, MA, United States of America; Harvard Medical School, Boston, MA, United States of America., van Kimmenade R; Cardiology Division, Radboud UMC, Nijmegen, the Netherlands., McCarthy CP; Massachusetts General Hospital, Boston, MA, United States of America; Harvard Medical School, Boston, MA, United States of America., Magaret CA; Prevencio, Inc., Kirkland, WA, United States of America., Barnes G; Prevencio, Inc., Kirkland, WA, United States of America., Rhyne RF; Prevencio, Inc., Kirkland, WA, United States of America., Gaggin HK; Massachusetts General Hospital, Boston, MA, United States of America; Harvard Medical School, Boston, MA, United States of America., Januzzi JL Jr; Massachusetts General Hospital, Boston, MA, United States of America; Harvard Medical School, Boston, MA, United States of America; Baim Institute for Clinical Research, Boston, MA, United States of America. Electronic address: jjanuzzi@partners.org.

Publikováno v: International journal of cardiology [Int J Cardiol] 2023 Jan 15; Vol. 371, pp. 402-405. Date of Electronic Publication: 2022 Oct 04.

Gaining Efficiency in Clinical Trials With Cardiac Biomarkers: JACC Review Topic of the Week.

Autor: Januzzi JL Jr; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Baim Institute for Clinical Research, Boston, Massachusetts, USA. Electronic address: jjanuzzi@partners.org., Canty JM; Division of Cardiovascular Medicine, University at Buffalo and Department of Veterans Affairs, Western New York Health Care System, Buffalo, New York, USA., Das S; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., DeFilippi CR; Inova Heart and Vascular Institute, Falls Church, Virginia, USA., Gintant GA; Department of Integrative Pharmacology, Integrated Sciences and Technology, AbbVie Pharmaceuticals, Cambridge, Massachusetts, USA., Gutstein DE; Cardiovascular Metabolism Discovery, Janssen Pharmaceuticals, Titusville, New Jersey, USA., Jaffe A; Department of Cardiovascular Diseases and Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Kaushik EP; Global Drug Safety Research and Evaluation, Takeda Pharmaceuticals, Boston, Massachusetts, USA., Leptak C; Biomarker Qualification Program, Office New Drugs, Center for Drug Development and Research, United States Food and Drug Administration, Silver Spring, Maryland, USA., Mehta C; Harvard TH Chan School of Public Health and Cytel Inc., Boston, Massachusetts, USA., Pina I; Wayne State University, Detroit, Michigan, USA., Povsic TJ; Duke Clinical Research Institute and Department of Medicine, Duke University, Durham, North Carolina, USA., Rambaran C; Daiichi-Sankyo, Inc., Basking Ridge, New Jersey, USA., Rhyne RF; Prevencio, Inc., Kirkland, Washington, USA., Salas M; Daiichi-Sankyo, Inc., Basking Ridge, New Jersey, USA; University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Shi VC; Novartis Pharmaceuticals Corporation, Basel, Switzerland., Udell JA; Cardiovascular Division, Women's College Hospital and Peter Munk Cardiac Centre, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada., Unger EF; Office of Cardiology, Hematology, Endocrinology, and Nephrology, Office of New Drugs, Center for Drug Development and Research, United States Food and Drug Administration, Silver Spring, Maryland, USA., Zabka TS; Development Sciences-Safety Assessment, Genentech Inc., San Francisco, California, USA., Seltzer JH; WCG Clinical and WCG-ACI Clinical, Bala Cynwood, Pennsylvania, USA.

Publikováno v: Journal of the American College of Cardiology [J Am Coll Cardiol] 2021 Apr 20; Vol. 77 (15), pp. 1922-1933.

Application of a machine learning-driven, multibiomarker panel for prediction of incident cardiovascular events in patients with suspected myocardial infarction.

Autor: Neumann JT; Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany., Sörensen NA; Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany., Zeller T; Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany., Magaret CA; Prevencio, Inc., Kirkland, WA 98034, USA., Barnes G; Prevencio, Inc., Kirkland, WA 98034, USA., Rhyne RF; Prevencio, Inc., Kirkland, WA 98034, USA., Peters C; Prevencio, Inc., Kirkland, WA 98034, USA., Goßling A; Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany., Hartikainen TS; Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany., Haller PM; Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany., Lehmacher J; Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany., Schäfer S; Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany., Januzzi JL; Massachusetts General Hospital, Division of Cardiology, Boston, MA 02114, USA.; Baim Institute for Clinical Research, Cardiometabolic Trials, Boston, MA 02115, USA., Westermann D; Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany.

Publikováno v: Biomarkers in medicine [Biomark Med] 2020 Jun; Vol. 14 (9), pp. 775-784. Date of Electronic Publication: 2020 May 28.

A clinical and proteomics approach to predict the presence of obstructive peripheral arterial disease: From the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) Study.

Autor: McCarthy CP; Department of Medicine, Massachusetts General Hospital, Boston., Ibrahim NE; Division of Cardiology, Massachusetts General Hospital, Boston., van Kimmenade RRJ; Division of Cardiology, Maastricht University Medical Centre, Maastricht, The Netherlands., Gaggin HK; Division of Cardiology, Massachusetts General Hospital, Boston.; Baim Institute for Clinical Research, Cardiometabolic Trials, Boston, Massachusetts., Simon ML; Division of Cardiology, Massachusetts General Hospital, Boston., Gandhi P; Division of Cardiology, VA Connecticut Healthcare System and Yale University, New Haven, Connecticut., Kelly N; Division of Cardiology, Brigham and Women's Hospital, Boston, Massachusetts., Motiwala SR; Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Mukai R; Division of Cardiology, Massachusetts General Hospital, Boston., Magaret CA; Prevencio, Inc., Washington., Barnes G; Prevencio, Inc., Washington., Rhyne RF; Prevencio, Inc., Washington., Garasic JM; Division of Cardiology, Massachusetts General Hospital, Boston., Januzzi JL Jr; Division of Cardiology, Massachusetts General Hospital, Boston.; Baim Institute for Clinical Research, Cardiometabolic Trials, Boston, Massachusetts.

Publikováno v: Clinical cardiology [Clin Cardiol] 2018 Jul; Vol. 41 (7), pp. 903-909. Date of Electronic Publication: 2018 Jun 14.