Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Rhonda Monahan"'
Autor:
Steve Finegan, Jennifer L. Liras, John Schafer, Gregory G. Stone, Sarah K. Wade, Ann G. Connolly, Rhonda Monahan, Katherine E. Brighty, Joan Duignan, Steven J. Brickner, Phuong Le, Ivan J. Samardjiev, Richard P. Zaniewski, Dennis Girard, Jon Bordner, Meghan Maloney
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:276-279
SAR studies and optimization of various modified Hygromycin A fluoroalkyl ethers, which led to the discovery of the highly potent 4'-(2-cyclopropyl-2-fluoroethyl ether) antibacterial CE-156811 (1) derived from truncation of the ribose ring and difluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31058e211b4e5cd78b92b592ecef72f
https://doi.org/10.1016/j.bmcl.2010.11.022
https://doi.org/10.1016/j.bmcl.2010.11.022
Autor:
Kevin Daniel Freeman-Cook, Katherine E. Brighty, Phuong Le, Michael Scott Visser, Gary J. Martinelli, Sarah K. Wade, Steven J. Brickner, Dianna E. Moore, Rhonda Monahan, Kyle T. Blair
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:6730-6734
Novel hygromycin A derivatives bearing a variety of functionalized aminocyclitol moieties have been synthesized in an effort to increase the antibacterial activity and drug-like properties of this class of agents. A systematic study of the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd3fd9b256be349e2e6da8955d6667d
https://doi.org/10.1016/j.bmcl.2010.08.139
https://doi.org/10.1016/j.bmcl.2010.08.139