Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rhonda L. Rolig"'
Publikováno v:
Mutagenesis. 13:357-365
We isolated and characterized the ERCC1 coding sequence from three Chinese hamster ovary (CHO) parental (CHO-AA8, CHO-AT3-2 and CHO-9) and 10 ERCC1 mutant cell lines. Two general classes of mutations were observed: two mutant cell lines exhibited nuc
Autor:
Gerald M. Adair, John H. Wilson, Rhonda L. Rolig, R. Geoffrey Sargent, April E. Kilburn, Rodney S. Nairn
Publikováno v:
Proceedings of the National Academy of Sciences. 94:13122-13127
Nucleotide excision repair proteins have been implicated in genetic recombination by experiments in Saccharomyces cerevisiae and Drosophila melanogaster , but their role, if any, in mammalian cells is undefined. To investigate the role of the nucleot
Autor:
Rhonda L. Rolig, Donald C. Morizot, Luis Della Coletta, Sallyanne Fossey, Ronald B. Walter, Rodney S. Nairn
Publikováno v:
Genomics. 26:70-76
We have cloned and sequenced the ERCC2/XPD locus of Xiphophorus maculatus. The human ERCC2/XPD gene is a nucleotide excision repair gene presumed to encode an ATP-dependent DNA helicase. The fish ERCC2/XPD gene is represented on 14.5 kb of genomic DN
Autor:
Dana Moore-Faver, Rhonda L. Rolig, Marina Zabelshansky, Gerald M. Adair, John H. Wilson, Rodney S. Nairn
The XpF/Ercc1 structure-specific endonuclease performs the 5' incision in nucleotide excision repair and is the apparent mammalian counterpart of the Rad1/Rad10 endonuclease from Saccharomyces cerevisiae. In yeast, Rad1/Rad10 endonuclease also functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5177db309ed8260fe833a2c4e9d00de
https://europepmc.org/articles/PMC313999/
https://europepmc.org/articles/PMC313999/
Autor:
Rhonda L Rolig, Peter J. McKinnon
Publikováno v:
Trends in neurosciences. 23(9)
Many human pathological conditions with genetic defects in DNA damage responses are also characterized by neurological deficits. These neurological deficits can manifest themselves during many stages of development, suggesting an important role for D
Autor:
Gerald M. Adair, Susan K. Layher, Feng Gu, Andrew J. Rainbow, Rodney S. Nairn, Rhonda L. Rolig, Barbara Santi
Publikováno v:
Mutagenesis. 12(4)
Positive selection-negative selection gene targeting was used to disrupt the nucleotide excision repair gene ERCC1 in a Chinese hamster ovary cell line, CHO-K1. Southern and Northern analysis showed that a cell clone isolated by this targeting approa