Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Rhonda L Feinbaum"'
Autor:
Read Pukkila-Worley, Rhonda L Feinbaum, Deborah L McEwan, Annie L Conery, Frederick M Ausubel
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004143 (2014)
Metazoans protect themselves from environmental toxins and virulent pathogens through detoxification and immune responses. We previously identified a small molecule xenobiotic toxin that extends survival of Caenorhabditis elegans infected with human
Externí odkaz:
https://doaj.org/article/aa21dd15ac8742598a05ffe09bf72b84
Autor:
Rhonda L Feinbaum, Jonathan M Urbach, Nicole T Liberati, Slavica Djonovic, Allison Adonizio, Anne-Ruxandra Carvunis, Frederick M Ausubel
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002813 (2012)
Pseudomonas aeruginosa strain PA14 is an opportunistic human pathogen capable of infecting a wide range of organisms including the nematode Caenorhabditis elegans. We used a non-redundant transposon mutant library consisting of 5,850 clones correspon
Externí odkaz:
https://doaj.org/article/6b9e2dc58e8944c5ac2de10edd06df48
Autor:
Javier E Irazoqui, Emily R Troemel, Rhonda L Feinbaum, Lyly G Luhachack, Brent O Cezairliyan, Frederick M Ausubel
Publikováno v:
PLoS Pathogens, Vol 6, p e1000982 (2010)
The genetically tractable model host Caenorhabditis elegans provides a valuable tool to dissect host-microbe interactions in vivo. Pseudomonas aeruginosa and Staphylococcus aureus utilize virulence factors involved in human disease to infect and kill
Externí odkaz:
https://doaj.org/article/76c0033378534fd5850f02fdbc4027f2
Autor:
Hilary K. Cheesman, Rhonda L. Feinbaum, Jose Thekkiniath, Robert H. Dowen, Annie L. Conery, Read Pukkila-Worley
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 3, Pp 541-549 (2016)
Inappropriate activation of innate immune responses in intestinal epithelial cells underlies the pathophysiology of inflammatory disorders of the intestine. Here we examine the physiological effects of immune hyperactivation in the intestine of the n
Externí odkaz:
https://doaj.org/article/ec0b738f833d4f8896352fa9e1572e2a
Autor:
Robert H. Dowen, Hilary K. Cheesman, Jose Thekkiniath, Annie L. Conery, Read Pukkila-Worley, Rhonda L. Feinbaum
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 3, Pp 541-549 (2016)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Inappropriate activation of innate immune responses in intestinal epithelial cells underlies the pathophysiology of inflammatory disorders of the intestine. Here we examine the physiological effects of immune hyperactivation in the intestine of the n
Autor:
Katherine A. Fitzgerald, Dennis H. Kim, Frederick M. Ausubel, Douglas T. Golenbock, Nicole T. Liberati, Rhonda L. Feinbaum
Publikováno v:
Proceedings of the National Academy of Sciences. 101:6593-6598
The p38 mitogen-activated protein kinase pathway regulates innate immune responses in evolutionarily diverse species. We have previously shown that the Caenorhabditis elegans p38 mitogen-activated protein kinase, PMK-1, functions in an innate immune
Publikováno v:
Cell. 116:S89-S92
Autor:
Victor R. Ambros, Rhonda L. Feinbaum
Publikováno v:
Developmental Biology. 210(1):87-95
The lin-4 gene encodes a small RNA that is required to translationally repress lin-14 toward the end of the first larval stage of Caenorhabditis elegans development. To determine if the timing of LIN-14 protein down-regulation depends on the temporal
Autor:
Deborah L. McEwan, Read Pukkila-Worley, Annie L. Conery, Frederick M. Ausubel, Rhonda L. Feinbaum
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 10, Iss 5, p e1004143 (2014)
PLoS Pathogens, Vol 10, Iss 5, p e1004143 (2014)
Metazoans protect themselves from environmental toxins and virulent pathogens through detoxification and immune responses. We previously identified a small molecule xenobiotic toxin that extends survival of Caenorhabditis elegans infected with human
Publikováno v:
Cell. 75:843-854
Summary h-4 is essential for the normal temporal control of diverse postembryonic developmental events in C. elegans. /in-4 acts by negatively regulating the level of LIN-14 protein, creating a temporal decrease in LIN-14 protein starting in the firs