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Autor:
Jamie Zagozewski, Stephanie Borlase, Brent J. Guppy, Ludivine Coudière-Morrison, Ghazaleh M. Shahriary, Victor Gordon, Lisa Liang, Stephen Cheng, Christopher J. Porter, Rhonda Kelley, Cynthia Hawkins, Jennifer A. Chan, Yan Liang, Jingjing Gong, Carolina Nör, Olivier Saulnier, Robert J. Wechsler-Reya, Vijay Ramaswamy, Tamra E. Werbowetski-Ogilvie
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
RNA sequencing of MEK inhibitor (selumetinib)-treated tumors reveals an upregulation of the JAK/STAT3 pathway, with combinatorial therapeutic strategies of JAK/STAT3 inhibitors and selumetinib investigated for the SHH subgroup of medulloblastoma.
Externí odkaz:
https://doaj.org/article/7089de720db644bf9d6c9ef8dd5e7822
