Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rhonda F, Rhyne"'
Autor:
Cian P. McCarthy, Johannes T. Neumann, Sam A. Michelhaugh, Nasrien E. Ibrahim, Hanna K. Gaggin, Nils A. Sörensen, Sarina Schäefer, Tanja Zeller, Craig A. Magaret, Grady Barnes, Rhonda F. Rhyne, Dirk Westermann, James L. Januzzi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 16 (2020)
Background Current noninvasive modalities to diagnose coronary artery disease (CAD) have several limitations. We sought to derive and externally validate a hs‐cTn (high‐sensitivity cardiac troponin)–based proteomic model to diagnose obstructive
Externí odkaz:
https://doaj.org/article/f2baa752ba934595b750d6242d5e7a88
Autor:
Curtis Rambaran, Gary Gintant, Rhonda F. Rhyne, Victor Shi, Tanja S. Zabka, James L. Januzzi, Saumya Das, David E. Gutstein, Ellis F. Unger, Christopher Leptak, Jonathan H. Seltzer, Allan S. Jaffe, Ileana L. Piña, Thomas J. Povsic, Jacob A. Udell, Cyrus R. Mehta, Emily Pfeiffer Kaushik, John M. Canty, Maribel Salas, Christopher DeFilippi
Publikováno v:
Journal of the American College of Cardiology. 77:1922-1933
The momentum of cardiovascular drug development has slowed dramatically. Use of validated cardiac biomarkers in clinical trials could accelerate development of much-needed therapies, but biomarkers have been used less for cardiovascular drug developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f647eaea221c1fe1deaac2fc73692fa1
https://doi.org/10.1016/j.jacc.2021.02.040
https://doi.org/10.1016/j.jacc.2021.02.040
Autor:
Raghav Gattani, Emmanuel Ekanem, Araba Ofosu-Somuah, Johannes T Neumann, Cian McCarthy, Palak Shah, Craig Magaret, Rhonda F Rhyne, Grady Barnes, Celine Peters, Dirk Westermann, Christopher Defilippi, James L Januzzi
Publikováno v:
Circulation. 144
Introduction: Diabetes Mellitus (DM) is a major risk factor for coronary artery disease (CAD) associated with a two-fold increase in mortality. We aimed to validate the performance of a machine learning based multi-biomarker diagnostic panel to predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2554d21f55408094a540a7fbc4940a9
https://doi.org/10.1161/circ.144.suppl_1.10637
https://doi.org/10.1161/circ.144.suppl_1.10637
Autor:
Johannes T Neumann, Rhonda F. Rhyne, Christopher DeFilippi, Cian P. McCarthy, Craig A. Magaret, James L. Januzzi, Dirk Westermann, Grady Barnes, N A Sorenson, Celine Peters
Publikováno v:
European Heart Journal. 42
Background Undetected obstructive coronary artery disease (oCAD) is a global health problem associated with significant morbidity and mortality. A need exists for an accurate and easily accessible diagnostic test for oCAD. Using machine learning, a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4592cb12026af5499709a2c8a9c06c63
https://doi.org/10.1093/eurheartj/ehab724.1374
https://doi.org/10.1093/eurheartj/ehab724.1374
Autor:
James L, Januzzi, John M, Canty, Saumya, Das, Christopher R, DeFilippi, Gary A, Gintant, David E, Gutstein, Allan, Jaffe, Emily P, Kaushik, Christopher, Leptak, Cyrus, Mehta, Ileana, Pina, Thomas J, Povsic, Curtis, Rambaran, Rhonda F, Rhyne, Maribel, Salas, Victor C, Shi, Jacob A, Udell, Ellis F, Unger, Tanja S, Zabka, Jonathan H, Seltzer
Publikováno v:
Journal of the American College of Cardiology. 77(15)
The momentum of cardiovascular drug development has slowed dramatically. Use of validated cardiac biomarkers in clinical trials could accelerate development of much-needed therapies, but biomarkers have been used less for cardiovascular drug developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76fc882b78dd9efbb144709c0cb31440
https://pubmed.ncbi.nlm.nih.gov/33858628
https://pubmed.ncbi.nlm.nih.gov/33858628
Autor:
Rhonda F. Rhyne, Inge C.L. van den Munckhof, Craig A. Magaret, Roland R.J. van Kimmenade, Leo A. B. Joosten, James L Januzzi, Joost H.W. Rutten, Niels P. Riksen, Mihai G. Netea
Publikováno v:
Circulation. 142
Introduction: Increased systemic inflammation is one of the key triggers in the initiation and progression of atherosclerosis. We investigated interleukin 18 binding protein (IL-18BP), a new inflammatory marker of the IL-1 cytokine family, on its pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cbf535fde16241288505f979b0eeb4c
https://doi.org/10.1161/circ.142.suppl_3.15495
https://doi.org/10.1161/circ.142.suppl_3.15495
Autor:
Sarina Schaefer, James L. Januzzi, Rhonda F. Rhyne, Dirk Westermann, Craig A. Magaret, Johannes T Neumann, Grady Barnes, Sam A. Michelhaugh, Cian P. McCarthy, Hanna K. Gaggin, Tanja Zeller, Nasrien E. Ibrahim, Nils A Sörensen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Current noninvasive modalities to diagnose coronary artery disease (CAD) have several limitations. We sought to derive and externally validate a hs‐cTn (high‐sensitivity cardiac troponin)–based proteomic model to diagnose obstructive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca1d000c760e0e7b8d4fe089bb77949
https://doi.org/10.1161/jaha.120.017221
https://doi.org/10.1161/jaha.120.017221
Autor:
Craig A. Magaret, James L. Januzzi, Johannes T Neumann, Celine Peters, Alina Goßling, Tanja Zeller, Dirk Westermann, Grady Barnes, Rhonda F. Rhyne, Paul M Haller, Sarina Schäfer, Tau S Hartikainen, Jonas Lehmacher, Nils A Sörensen
Publikováno v:
Biomarkers in medicine. 14(9)
Background: In patients with suspected myocardial infarction (MI), we sought to validate a machine learning-driven, multibiomarker panel for prediction of incident major adverse cardiovascular events (MACE). Methodology & results: A previously descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba55dd961e1ae0d7ca18eb6da7be406
https://pubmed.ncbi.nlm.nih.gov/32462911
https://pubmed.ncbi.nlm.nih.gov/32462911
Autor:
Joseph M. Garasic, Shreya Shrestha, Cian P. McCarthy, Nasrien E. Ibrahim, Roland R.J. van Kimmenade, James L. Januzzi, Renata Mukai, Rhonda F. Rhyne, Craig A. Magaret, Grady Barnes, Hanna K. Gaggin
Publikováno v:
Open Heart, 6, e000955
Open Heart, 6, 1, pp. e000955
Open Heart
Open Heart, 6, 1, pp. e000955
Open Heart
BackgroundPatients with diabetes mellitus (DM) are at substantial risk of developing peripheral artery disease (PAD). We recently developed a clinical/proteomic panel to predict obstructive PAD. In this study, we compare the accuracy of this panel fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989fc76f1731d4cf3b8a719f6367e060
http://hdl.handle.net/2066/209487
http://hdl.handle.net/2066/209487
Autor:
Grady Barnes, Dirk Westermann, Craig A. Magaret, Christopher DeFilippi, Johannes T Neumann, Palak Shah, James L. Januzzi, Emmanuel Ekanem, Rhonda F. Rhyne, Cian P. McCarthy
Publikováno v:
Journal of the American College of Cardiology. 77:20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::152a295cfbcb2704e72338fdf5a52a9f
https://doi.org/10.1016/s0735-1097(21)01379-6
https://doi.org/10.1016/s0735-1097(21)01379-6