Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Rhona Mirsky"'
Autor:
Matthew B. Wilcox, Simão G Laranjeira, Tuula M. Eriksson, Kristjan R. Jessen, Rhona Mirsky, Tom J. Quick, James B. Phillips
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Nerve regeneration is a key biological process in those recovering from neural trauma. From animal models it is known that the regenerative capacity of the peripheral nervous system (PNS) relies heavily on the remarkable ability of Schwann c
Externí odkaz:
https://doaj.org/article/8760e4c4beaf415c952018e1d65e59b8
Autor:
Kristjan R. Jessen, Rhona Mirsky
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
After nerve injury, both Schwann cells and neurons switch to pro-regenerative states. For Schwann cells, this involves reprogramming of myelin and Remak cells to repair Schwann cells that provide the signals and mechanisms needed for the survival of
Externí odkaz:
https://doaj.org/article/fbf93b73b174483da115022152029527
Autor:
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Publikováno v:
eLife, Vol 10 (2021)
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that results from slow axon g
Externí odkaz:
https://doaj.org/article/71cf5cebbc4d40f8b6b3a29c0b196abc
Autor:
Peter J. Arthur-Farraj, Claire C. Morgan, Martyna Adamowicz, Jose A. Gomez-Sanchez, Shaline V. Fazal, Anthony Beucher, Bonnie Razzaghi, Rhona Mirsky, Kristjan R. Jessen, Timothy J. Aitman
Publikováno v:
Cell Reports, Vol 20, Iss 11, Pp 2719-2734 (2017)
Repair Schwann cells play a critical role in orchestrating nerve repair after injury, but the cellular and molecular processes that generate them are poorly understood. Here, we perform a combined whole-genome, coding and non-coding RNA and CpG methy
Externí odkaz:
https://doaj.org/article/b1df5bc580954457aa1f44a8b2ac5ad5
Autor:
Kristjan R. Jessen, Rhona Mirsky
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
The cells of the neural crest, often referred to as neural crest stem cells, give rise to a number of sub-lineages, one of which is Schwann cells, the glial cells of peripheral nerves. Crest cells transform to adult Schwann cells through the generati
Externí odkaz:
https://doaj.org/article/eeebcd833f5545af9caa37615b07bca0
Autor:
Kristjan R. Jessen, Rhona Mirsky
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The remarkable plasticity of Schwann cells allows them to adopt the Remak (non-myelin) and myelin phenotypes, which are specialized to meet the needs of small and large diameter axons, and differ markedly from each other. It also enables Schwann cell
Externí odkaz:
https://doaj.org/article/cf36e36488f34240ba5cddbd19fb4951
Publikováno v:
Neurobiology of Disease, Vol 24, Iss 1, Pp 159-169 (2006)
Mutations in the DNA-binding domain of EGR2 are associated with severe autosomal dominant forms of peripheral neuropathy. In this study, we show that one such Egr2 mutant (S382R, D383Y), when expressed in Schwann cells in vitro, is not transcriptiona
Externí odkaz:
https://doaj.org/article/be22fb6f3adc4e5e94edd6f03abf12f0
Publikováno v:
Myelin ISBN: 9780203746141
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3072bd0136e33ba6053263e9ced76888
https://doi.org/10.1201/9780203746141-5
https://doi.org/10.1201/9780203746141-5
Autor:
Shaline V. Fazal, Georg W. Otto, Peter Arthur-Farraj, Sergio Velasco-Aviles, Jose A. Gomez-Sanchez, Cristina Benito, Mark Turmaine, Rhona Mirsky, Liam Yn Wong, Kirolos Michael, Hugo Cabedo, Alastair M. Kilpatrick, Tessa Gordon, Kristjan R. Jessen, Ki H. Ma, Laura Wagstaff, John Svaren
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
eLife
eLife, Vol 10 (2021)
Wagstaff, L J, Gomez-Sanchez, J A, Fazal, S V, Otto, G W, Kilpatrick, A M, Michael, K, Wong, L YN, Ma, K H, Turmaine, M, Svaren, J, Gordon, T, Arthur-Farraj, P, Velasco-Aviles, S, Cabedo, H, Benito, C, Mirsky, R & Jessen, K R 2021, ' Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun ', eLIFE, vol. 10 . https://doi.org/10.7554/eLife.62232
instname
eLife
eLife, Vol 10 (2021)
Wagstaff, L J, Gomez-Sanchez, J A, Fazal, S V, Otto, G W, Kilpatrick, A M, Michael, K, Wong, L YN, Ma, K H, Turmaine, M, Svaren, J, Gordon, T, Arthur-Farraj, P, Velasco-Aviles, S, Cabedo, H, Benito, C, Mirsky, R & Jessen, K R 2021, ' Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun ', eLIFE, vol. 10 . https://doi.org/10.7554/eLife.62232
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that results from slow axon g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21724dc2acf9c6f275b3d775968dd8a
https://doi.org/10.7554/elife.62232
https://doi.org/10.7554/elife.62232