Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rhona Aird"'
Autor:
Sofia Ferreira-Gonzalez, Tak Yung Man, Hannah Esser, Rhona Aird, Alastair M. Kilpatrick, Daniel Rodrigo-Torres, Nicholas Younger, Lara Campana, Victoria L. Gadd, Benjamin Dwyer, Niya Aleksieva, Luke Boulter, Mark T. Macmillan, Yinmiao Wang, Katie J. Mylonas, David A. Ferenbach, Timothy J. Kendall, Wei-Yu Lu, Juan Carlos Acosta, Dominic Kurian, Stephen O’Neill, Gabriel C. Oniscu, Jesus M. Banales, Paul J. Krimpenfort, Stuart J. Forbes
Publikováno v:
Ferreira-Gonzalez, S, Man, T Y, Esser, H, Aird, R, Kilpatrick, A, Rodrigo Torres, D, Younger, N, Campana, L, Gadd, V, Dwyer, B, Aleksieva, N, Boulter, L, Macmillan, M, Wang, Y, Mylonas, K J, Ferenbach, D A, Kendall, T J, Lu, W-Y, Acosta, J C, Kurian, D, O'Neill, S, Oniscu, G, Banales, J M, Krimpenfort, P & Forbes, S J 2022, ' Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage ', Science Translational Medicine, vol. 14, no. 674, eabj4375 . https://doi.org/10.1126/scitranslmed.abj4375
Liver transplantation is the only curative option for patients with end-stage liver disease. Despite improvements in surgical techniques, nonanastomotic strictures (characterized by the progressive loss of biliary tract architecture) continue to occu
Autor:
Amy Schofield, Philip J. Starkey Lewis, Rhona Aird, Ian M. Copple, Fang Zhang, B. Kevin Park, Christopher E. Goldring, Tobias M Bunday, Stephen W. Fenwick, Yongxiang Fang, Shiva S. Forootan, Harish Poptani, Mohamed Elmasry, Emanuele Ricci, Hassan Malik, Jack Sharkey, Neil R. Kitteringham, Giusy Russomanno, Timothy Andrews, Nathalie Brillant, Benjamin K Y Chan, Adam Lister, Stuart J. Forbes, Rowena Sison-Young
Publikováno v:
Hepatology. 74:973-986
Background and aims The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) regulates an array of cytoprotective genes, yet studies in transgenic mice have led to conflicting reports on its role in liver regeneration. We aimed to
Autor:
Alison C. MacKinnon, Lara Campana, Jennifer A Cartwright, Timothy J. Kendall, Rhona Aird, Lesley M. Forrester, Victoria L. Gadd, Adrian Thomson, Tak-Yung Man, Niya Aleksieva, Philip J. Starkey Lewis, Stuart J. Forbes, Eoghan O'Duibhir, Matthieu Vermeren, Adriano G. Rossi, Benjamin J. Dwyer, B. Kevin Park
Publikováno v:
Journal of Hepatology
Background & Aim Following acetaminophen (APAP) overdose, acute liver injury (ALI) can occur in patients that present too late for N-acetylcysteine treatment, potentially leading to acute liver failure, systemic inflammation, and death. Macrophages i
Publikováno v:
Endocrine Abstracts.
Autor:
Sergio Rodriguez-Cuenca, Gary A. Churchill, Antonio Vidal-Puig, Maximilian Zeyda, Nicholas M. Morton, Annalisa Gastaldello, Jasmina Beltram, Scott P. Webster, Gregor Gorjanc, Aila Saari, Thomas M. Stulnig, Simon Horvat, Vilmundur Gudnason, Roderick N. Carter, Matthew T G Gibbins, José Manuel Fernández-Real, Jonathan R. Seckl, Steven C. Munger, Clare McFadden, Gregorio Naredo, Martin E. Barrios-Llerena, Donald R. Dunbar, Christopher J Kenyon, Zhao V. Wang, Alexander F. Howie, Lynne Ramage, José María Moreno-Navarrete, Karen L. Svenson, Brian R. Walker, Valur Emilsson, Petra Sipilä, Zoi Michailidou, Rhona Aird
Publikováno v:
Morton, N M, Beltram, J, Carter, R N, Michailidou, Z, Gorjanc, G, McFadden, C, Barrios-Llerena, M E, Rodriguez-Cuenca, S, Gibbins, M T G, Aird, R E, Moreno-Navarrete, J M, Munger, S C, Svenson, K L, Gastaldello, A, Ramage, L, Naredo, G, Zeyda, M, Wang, Z V, Howie, A F, Saari, A, Sipilä, P, Stulnig, T M, Gudnason, V, Kenyon, C J, Seckl, J R, Walker, B R, Webster, S P, Dunbar, D R, Churchill, G A, Vidal-Puig, A, Fernandez-Real, J M, Emilsson, V & Horvat, S 2016, ' Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness ', Nature Medicine, vol. 22, no. 7, pp. 771-779 . https://doi.org/10.1038/nm.4115
Nature medicine
© Nature Medicine, 2016, vol. 22, p. 771-779
Articles publicats (D-CM)
DUGiDocs – Universitat de Girona
instname
Nature medicine
© Nature Medicine, 2016, vol. 22, p. 771-779
Articles publicats (D-CM)
DUGiDocs – Universitat de Girona
instname
The discovery of genetic mechanisms for resistance to obesity and diabetes may illuminate new therapeutic strategies for the treatment of this global health challenge. We used the polygenic 'lean' mouse model, which has been selected for low adiposit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d97883a5e7915270071cddd2f0f72e6
https://hdl.handle.net/2072/372198
https://hdl.handle.net/2072/372198
Autor:
R. Balfour Sartor, Rhona Aird, Bo Liu, Takahiko Shimizu, Jack Satsangi, Ray Boyapati, Nicholas A. Kennedy, Gwo-Tzer Ho
Publikováno v:
Gastroenterology. 152:S962-S963
Autor:
Martin E. Barrios-Llerena, Petra Sipilä, Annalisa Gastaldello, Sergio Rodriguez-Cuenca, José Manuel Fernández-Real, Rhona Aird, Gregor Gorjanc, Jasmina Beltram, Zoi Michailidou, Thomas M. Stulnig, Gary A. Churchill, Zhao V. Wang, Nicholas M. Morton, Clare McFadden, Aila Saari, Maximilian Zeyda, Vilmundur Gudnason, Donald R. Dunbar, Simon Horvat, Christopher J. Kenyon, José María Moreno-Navarrete, Antonio Vidal-Puig, Brian R. Walker, Valur Emilsson, Jonathan R. Seckl, Steven C. Munger, Karen L. Svenson, Lynne Ramage, Roderick N. Carter, Matthew T G Gibbins, Gregorio Naredo, Alexander F. Howie, Scott P. Webster
Publikováno v:
Nature Medicine. 24:525-525
Nat. Med. 22, 771–779 (2016); published online 6 June 2016; corrected after print 7 March 2018 In the version of this article initially published, the colors of the lines were switched in the graph that shows the glucose infusion rates for wild-typ
Autor:
U. Prabhakar, R. Vora, M. Nakada, M. DeWitte, R. E. Corringham, C. Sturgeon, Duncan I. Jodrell, S. A. Hoare, Ewan Brown, John F. Smyth, David Propper, Frances R. Balkwill, Rhona Aird, Kellie A. Charles, R. L. Rye
Publikováno v:
Annals of Oncology. 19:1340-1346
Background Tumour necrosis factor-α (TNF-α) is an important regulator of the chronic inflammation contributing to tumour progression. Infliximab, an anti-TNF-α monoclonal antibody was investigated in this trial of patients with advanced cancer. Th
Autor:
David E. Thurston, Janet S. Macpherson, Marian Thomson, Rhona Aird, Duncan I. Jodrell, Sylvie Guichard
Publikováno v:
The Pharmacogenomics Journal. 8:289-296
ATP-binding cassette transporter P-glycoprotein (ABCB1) is responsible for the multidrug resistance (MDR1) phenotype observed in cancer cells. SJG-136, a new pyrrolobenzodiazepine dimer, is a sequence-dependent DNA crosslinking agent and substrate of
Autor:
Rhona Aird, Francesca P. A. Fabbiani, James E. Davidson, Abraha Habtemariam, Andrew Parkin, Iain D. H. Oswald, Simon Parsons, Rafael Fernández, Michael Melchart, Alice Dawson, Peter J. Sadler, Duncan I. Jodrell
Publikováno v:
Journal of medicinal chemistry. 49(23)
We report structure-activity relationships for organometallic RuII complexes of the type [(eta6-arene)Ru(XY)Cl]Z, where XY is an N,N- (diamine), N,O- (e.g., amino acidate), or O,O- (e.g., beta-diketonate) chelating ligand, the arene ranges from benze