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of 3
pro vyhledávání: '"Rhodri O. Williams"'
Autor:
Ahmed G. Eissa, James A. Blaxland, Rhodri O. Williams, Kamel A. Metwally, Sobhy M. El-Adl, El-Sayed M. Lashine, Leslie W.J. Baillie, Claire Simons
Publikováno v:
Bulletin of Faculty of Pharmacy Cairo University, Vol 54, Iss 2, Pp 197-207 (2016)
As part of our ongoing research efforts to develop new antibacterial agents acting on novel molecular targets, a series of twenty-two adenine and benzimidazole-based mimics of the lead compound REP-3123 was designed to target methionyl-tRNA synthetas
Externí odkaz:
https://doaj.org/article/9cd58432d92247aa94f77adeedd8e564
Autor:
Rhodri O. Williams, Ahmed G. Eissa, James A. Blaxland, Kamel Metwally, El-Sayed M. Lashine, Leslie W.J. Baillie, Claire Simons, Sobhy M. El-Adl
The synthesis of a series of benzimidazole-N-benzylpropan-1-amines and adenine-N-benzylpropan-1-amines is described. Subsequent evaluation against two strains of the anaerobic bacterium Clostridium difficile was performed with three amine derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b12303169bb6a89da1284c3068028a5
https://orca.cardiff.ac.uk/id/eprint/87911/2/Targeting%20methionyl%20tRNA%20synthetase-%20design%2C%20synthesis%20and%20antibacterial%20activity%20against%20Clostridium%20difficile%20of%20novel%203-biaryl-N-benzylpropan-1-amine%20derivatives.pdf
https://orca.cardiff.ac.uk/id/eprint/87911/2/Targeting%20methionyl%20tRNA%20synthetase-%20design%2C%20synthesis%20and%20antibacterial%20activity%20against%20Clostridium%20difficile%20of%20novel%203-biaryl-N-benzylpropan-1-amine%20derivatives.pdf
Autor:
El-Sayed M. Lashine, Sobhy M. El-Adl, Claire Simons, Kamel Metwally, James A. Blaxland, Rhodri O. Williams, Ahmed G. Eissa, Leslie W.J. Baillie
Publikováno v:
Bulletin of Faculty of Pharmacy, Cairo University, Vol 54, Iss 2, Pp 197-207 (2016)
As part of our ongoing research efforts to develop new antibacterial agents acting on novel molecular targets, a series of twenty-two adenine and benzimidazole-based mimics of the lead compound REP-3123 was designed to target methionyl-tRNA synthetas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75897aa726cfe3e0d02067733b6d590d