Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Rhoderick H Elder"'
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26174ef861fb34ffa0c1b8fbfe09ac1a
https://doi.org/10.1096/fasebj.2019.33.1_supplement.lb186
https://doi.org/10.1096/fasebj.2019.33.1_supplement.lb186
Autor:
Rhoderick H. Elder, Soran Mohammed, Mustafa S. Albelazi, Luciano Mutti, Jason L. Parsons, Peter R. Martin
Publikováno v:
GENES
Genes
Volume 10
Issue 4
Genes, Vol 10, Iss 4, p 315 (2019)
Genes
Volume 10
Issue 4
Genes, Vol 10, Iss 4, p 315 (2019)
Endonuclease VIII-like (NEIL) 1 and 3 proteins eliminate oxidative DNA base damage and psoralen DNA interstrand crosslinks through initiation of base excision repair. Current evidence points to a DNA replication associated repair function of NEIL1 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b7d12c0cfe6fcc710010aee37c27fe
Autor:
Peter R, Martin, Sophie, Couvé, Caroline, Zutterling, Mustafa S, Albelazi, Regina, Groisman, Bakhyt T, Matkarimov, Jason L, Parsons, Rhoderick H, Elder, Murat K, Saparbaev
Publikováno v:
Scientific Reports
Interstrand cross-links (ICLs) are highly cytotoxic DNA lesions that block DNA replication and transcription by preventing strand separation. Previously, we demonstrated that the bacterial and human DNA glycosylases Nei and NEIL1 excise unhooked psor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4bca2f7bbcc17c2907ce762b7eddc8c
https://pubmed.ncbi.nlm.nih.gov/29234069
https://pubmed.ncbi.nlm.nih.gov/29234069
Publikováno v:
Toxicology. 268:111-117
The DNA structure recognition protein MSH2 is an important protein in DNA mismatch repair due to its role in initiating the repair process. To examine the potential interactions between mismatch repair and base excision repair (BER) we have examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae48c3f5f43d760e207b07a8e8c30017
https://doi.org/10.1016/j.tox.2009.12.008
https://doi.org/10.1016/j.tox.2009.12.008
Autor:
James A. Swenberg, Rhoderick H. Elder, Valeriy Afonin, Keizo Tano, Jun Nakamura, Shunichi Takeda, Masami Watanabe, Brian F. Pachkowski
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 671:93-99
Poly(ADP-ribose) polymerase-1 (PARP-1) is a base excision repair (BER) protein that binds to DNA single strand breaks (SSBs) and subsequently synthesizes and transfers poly(ADP-ribose) polymers to various nuclear proteins. Numerous biochemical studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79676a78b8b863d1117b2c1f4692470
https://doi.org/10.1016/j.mrfmmm.2009.09.006
https://doi.org/10.1016/j.mrfmmm.2009.09.006
Publikováno v:
The FASEB Journal. 19:1-18
OGG-1 DNA glycosylase (OGG-1) is an enzyme involved in DNA repair. It excises 7,8-dihydro-8-oxoguanine, which is formed by oxidative damage of guanine. We have investigated the role of OGG-1 in inflammation using three models of inflammation: endotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a011935b091c0016ce2db0611093589
https://doi.org/10.1096/fj.04-2278fje
https://doi.org/10.1096/fj.04-2278fje
Autor:
Grigory L. Dianov, Rhoderick H. Elder
Publikováno v:
Journal of Biological Chemistry. 277:50487-50490
In mammalian cells, thymine glycols and other oxidized pyrimidines such as 5,6-dihydrouracil are removed from DNA by the NTH1 protein, a bifunctional DNA-N-glycosylase. However, mNTH1 knock-out mice in common with other DNA glycosylase-deficient mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b1fe7df4f5e5905ca3a29d96844e27
https://doi.org/10.1074/jbc.m208153200
https://doi.org/10.1074/jbc.m208153200
Autor:
Allen P. Yates, Rhoderick H Elder, Kurt J. Mynett, Geoffrey P. Margison, John Cardinal, Donald P. Cameron
Publikováno v:
Molecular and Cellular Biology. 21:5605-5613
Type 1 diabetes is thought to occur as a result of the loss of insulin-producing pancreatic beta cells by an environmentally triggered autoimmune reaction. In rodent models of diabetes, streptozotocin (STZ), a genotoxic methylating agent that is targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a47a9b3c45bc95f1c907106fa0ece4
https://doi.org/10.1128/mcb.21.16.5605-5613.2001
https://doi.org/10.1128/mcb.21.16.5605-5613.2001
Autor:
Rhoderick H. Elder, Geoffrey P. Margison, B. Deans, C J Herring, J MacKinnon, Joseph A Rafferty, Ian D. Hickson, Jolyon H Hendry, G Barzilay
Publikováno v:
British Journal of Cancer
Apurinic/apyrimidinic (AP) sites in DNA are potentially lethal and mutagenic. They can arise spontaneously or following DNA damage from reactive oxygen species or alkylating agents, and they constitute a significant product of DNA damage following ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a6bf97bed37b8167f8a91a3a6578ad
https://doi.org/10.1038/sj.bjc.6690447
https://doi.org/10.1038/sj.bjc.6690447
Publikováno v:
Proceedings of the National Academy of Sciences. 94:12869-12874
It has previously been reported that 1, N 6 -ethenoadenine (ɛA), deaminated adenine (hypoxanthine, Hx), and 7,8-dihydro-8-oxoguanine (8-oxoG), but not 3, N 4 -ethenocytosine (ɛC), are released from DNA in vitro by the DNA repair enzyme alkylpurine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13ee0ccbc5fa2c01308a0d934d9d6712
https://doi.org/10.1073/pnas.94.24.12869
https://doi.org/10.1073/pnas.94.24.12869