Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Rhoderick E. Brown"'
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 1, Pp 100151- (2022)
Lipid transfer proteins acquire and release their lipid cargoes by interacting transiently with source and destination biomembranes. In the GlycoLipid Transfer Protein (GLTP) superfamily, the two-layer all-α-helical GLTP-fold defines proteins that s
Externí odkaz:
https://doaj.org/article/9e1528764da6447b8402017f8db445a2
Autor:
Dhirendra K. Simanshu, Xiuhong Zhai, David Munch, Daniel Hofius, Jonathan E. Markham, Jacek Bielawski, Alicja Bielawska, Lucy Malinina, Julian G. Molotkovsky, John W. Mundy, Dinshaw J. Patel, Rhoderick E. Brown
Publikováno v:
Cell Reports, Vol 6, Iss 2, Pp 388-399 (2014)
The accelerated cell death 11 (acd11) mutant of Arabidopsis provides a genetic model for studying immune response activation and localized cellular suicide that halt pathogen spread during infection in plants. Here, we elucidate ACD11 structure and f
Externí odkaz:
https://doaj.org/article/d44452172639457987ee1386b90c25cd
Autor:
Xiuhong Zhai, William E. Momsen, Dmitry A. Malakhov, Ivan A. Boldyrev, Maureen M. Momsen, Julian G. Molotkovsky, Howard L. Brockman, Rhoderick E. Brown
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 4, Pp 1103-1113 (2013)
Among amphitropic proteins, human glycolipid transfer protein (GLTP) forms a structurally-unique fold that translocates on/off membranes to specifically transfer glycolipids. Phosphatidylcholine (PC) bilayers with curvature-induced packing stress sti
Externí odkaz:
https://doaj.org/article/787e42bfefbe4363b0ca6b8d89b09d05
Autor:
Ivan A. Boldyrev, Xiuhong Zhai, Maureen M. Momsen, Howard L. Brockman, Rhoderick E. Brown, Julian G. Molotkovsky
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 7, Pp 1518-1532 (2007)
Many fluorescent lipid probes tend to loop back to the membrane interface when attached to a lipid acyl chain rather than embedding deeply into the bilayer. To achieve maximum embedding of BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) fluoropho
Externí odkaz:
https://doaj.org/article/1aadd7ec5b6046bbaef1f60fda54e44c
Autor:
István P. Sugár, Xiuhong Zhai, Ivan A. Boldyrev, Julian G. Molotkovsky, Howard L. Brockman, Rhoderick E. Brown
Publikováno v:
International Journal of Biomedical Imaging, Vol 2010 (2010)
Lipid lateral organization in binary-constituent monolayers consisting of fluorescent and nonfluorescent lipids has been investigated by acquiring multiple emission spectra during measurement of each force-area isotherm. The emission spectra reflect
Externí odkaz:
https://doaj.org/article/a3eef40492104e4b891e39b0e97ba2de
Autor:
Yong-Guang Gao, Alexander Tischer, Rhoderick E. Brown, Xiuhong Zhai, Atsushi Nishida, Shrawan K. Mishra, Toshihiko Murayama, Amer Alam, Julian G. Molotkovsky, Ivan A. Boldyrev, Le Thi My Le
Publikováno v:
Anal Chem
In vitro assessment of lipid intermembrane transfer activity by cellular proteins typically involves measurement of either radiolabeled or fluorescently labeled lipid trafficking between vesicle model membranes. Use of bilayer vesicles in lipid trans
Autor:
Yoshinori Hirano, Yong-Guang Gao, Daniel J Stephenson, Ngoc T Vu, Lucy Malinina, Dhirendra K Simanshu, Charles E Chalfant, Dinshaw J Patel, Rhoderick E Brown
Publikováno v:
eLife, Vol 10 (2021)
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 1, Pp 100151-(2022)
Lipid transfer proteins acquire and release their lipid cargoes by interacting transiently with source and destination biomembranes. In the GlycoLipid Transfer Protein (GLTP) superfamily, the two-layer all-α-helical GLTP-fold defines proteins that s
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1864:158-167
Human GLTP on chromosome 12 (locus 12q24.11) encodes a 24 kD amphitropic lipid transfer protein (GLTP) that mediates glycosphingolipid (GSL) intermembrane trafficking and regulates GSL homeostatic levels within cells. Herein, we provide evidence that
Autor:
Charles E. Chalfant, Dinshaw J. Patel, Lucy Malinina, Daniel J. Stephenson, Yoshinori Hirano, Dhirendra K. Simanshu, Ngoc T. Vu, Yong-Guang Gao, Rhoderick E. Brown
Publikováno v:
BIO-PROTOCOL. 11
Previous expression/purification strategies for cytosolic phospholipase A2α C2-domain in Escherichia coli have relied on refolded protein recovered from inclusion bodies and sometimes containing C-terminal Cys139Ala and Cys141Ser substitutions to el