Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Rhoda Stefanatos"'
Autor:
Filippo Scialò, Ashwin Sriram, Rhoda Stefanatos, Ruth V. Spriggs, Samantha H.Y. Loh, L. Miguel Martins, Alberto Sanz
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Reactive Oxygen Species (ROS) are essential cellular messengers required for cellular homeostasis and regulate the lifespan of several animal species. The main site of ROS production is the mitochondrion, and within it, respiratory complex I (CI) is
Externí odkaz:
https://doaj.org/article/19ecc0b6012c48ba9888fe74cef8cc9d
Autor:
Bernadette Carroll, Elsje G. Otten, Diego Manni, Rhoda Stefanatos, Fiona M. Menzies, Graham R. Smith, Diana Jurk, Niall Kenneth, Simon Wilkinson, Joao F. Passos, Johannes Attems, Elizabeth A. Veal, Elisa Teyssou, Danielle Seilhean, Stéphanie Millecamps, Eeva-Liisa Eskelinen, Agnieszka K. Bronowska, David C. Rubinsztein, Alberto Sanz, Viktor I. Korolchuk
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The cellular mechanisms underlying autophagy are conserved; however it is unclear how they evolved in higher organisms. Here the authors identify two oxidation-sensitive cysteine residues in the autophagy receptor SQSTM1/p62 in vertebrates which allo
Externí odkaz:
https://doaj.org/article/9d95b336540a41c68ad4e7b54566d6ac
Publikováno v:
Cell Stress, Vol 2, Iss 4, Pp 91-93 (2018)
Ageing and age-related diseases are characterised by increased oxidative and proteotoxic stress, which results in negative effects on cell function and survival. The cell possesses several mechanisms to deal with damaged proteins, including degradati
Externí odkaz:
https://doaj.org/article/507ad931f9d244b1831e10b59858d402
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161817 (2016)
Drosophila melanogaster is a popular research model organism thanks to its' powerful genetic tools that allow spatial and temporal control of gene expression. The inducible GeneSwitch Gal4 system (GS) system is a modified version of the classic UAS/G
Externí odkaz:
https://doaj.org/article/ccf90f9a4f9a4c1bb2464aa2969c55f9
Autor:
Tetsushi Kataura, Lucia Sedlackova, Elsje G. Otten, Ruchika Kumari, David Shapira, Filippo Scialo, Rhoda Stefanatos, Kei-ichi Ishikawa, George Kelly, Elena Seranova, Congxin Sun, Dorothea Maetzel, Niall Kenneth, Sergey Trushin, Tong Zhang, Eugenia Trushina, Charles C. Bascom, Ryan Tasseff, Robert J. Isfort, John E. Oblong, Satomi Miwa, Michael Lazarou, Rudolf Jaenisch, Masaya Imoto, Shinji Saiki, Manolis Papamichos-Chronakis, Ravi Manjithaya, Oliver D.K. Maddocks, Alberto Sanz, Sovan Sarkar, Viktor I. Korolchuk
Publikováno v:
Developmental cell. 57(22)
Autophagy is an essential catabolic process that promotes the clearance of surplus or damaged intracellular components. Loss of autophagy in age-related human pathologies contributes to tissue degeneration through a poorly understood mechanism. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc508f76873fc202b33a7371d31c3b20
https://pubmed.ncbi.nlm.nih.gov/36413951
https://pubmed.ncbi.nlm.nih.gov/36413951
Autor:
Tetsushi Kataura, Lucia Sedlackova, Elsje G. Otten, David Shapira, Filippo Scialo, Rhoda Stefanatos, Kei-ichi Ishikawa, George Kelly, Elena Seranova, Congxin Sun, Dorothea Maetzel, Niall Kenneth, Sergey Trushin, Tong Zhang, Eugenia Trushina, Charles C. Bascom, Ryan Tasseff, Robert J. Isfort, John E. Oblong, Satomi Miwa, Michael Lazarou, Rudolf Jaenisch, Masaya Imoto, Shinji Saiki, Manolis Papamichos-Chronakis, Oliver D.K. Maddocks, Alberto Sanz, Sovan Sarkar, Viktor Korolchuk
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48c9c128ca1510167141f3fa3fcd4667
https://doi.org/10.2139/ssrn.4034887
https://doi.org/10.2139/ssrn.4034887
Autor:
Filippo Scialò, Oliver D. K. Maddocks, Angeline E.H. Yek, Rhoda Stefanatos, Tong Zhang, L. Miguel Martins, Alejandro Huerta Uribe, Alberto Sanz, Charlotte Graham, Ruth V. Spriggs, Samantha H. Y. Loh
Mitochondrial Reactive Oxygen Species (mtROS) are cellular messengers essential for cellular homeostasis. In response to stress, reverse electron transport (RET) by respiratory complex I generates high levels of mtROS. Suppression of ROS produced via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98b04a1babf18eceb4c3f1f9365db350
https://doi.org/10.1101/2021.08.18.456795
https://doi.org/10.1101/2021.08.18.456795
Autor:
Thiago Varga, Elsje G. Otten, Filippo Scialò, Gareth G. Lavery, Daniel G. Anderson, Shinji Saiki, Ryan Tasseff, Oliver D. K. Maddocks, David Cartwright, Niall S. Kenneth, Congxin Sun, Joerg Gsponer, Carl Ward, Luiz Felipe Souza E Silva, Rudolf Jaenisch, Tatiana R. Rosenstock, Manolis Papamichos-Chronakis, Malgorzata Zatyka, Kei-Ichi Ishikawa, Elena Seranova, Dorothea Maetzel, Sovan Sarkar, Masaya Imoto, Michael Lazarou, Haoyi Wang, David Shapira, Adina Maria Palhegyi, Kevin J. Kauffman, Rhoda Stefanatos, Malkiel A. Cohen, Lucia Sedlackova, Robert J. Isfort, Prashanta Kumar Panda, Tetsushi Kataura, Charles C. Bascom, Miruna Chipara, Gaurav Sahay, Alberto Sanz, Yosef Buganim, John Erich Oblong, Shupei Zhang, Satomi Miwa, Tong Zhang, Animesh Acharjee, Viktor I. Korolchuk, Jorge Torresi
Autophagy is an essential catabolic process that promotes the clearance of surplus or damaged intracellular components1. As a recycling process, autophagy is also important for the maintenance of cellular metabolites to aid metabolic homeostasis2. Lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f2832b802172e30ef5e271ca98c298b
https://doi.org/10.21203/rs.3.rs-659023/v1
https://doi.org/10.21203/rs.3.rs-659023/v1
Publikováno v:
Mitochondrial Diseases ISBN: 9783030701468
The central role of mitochondria in cell metabolism and physiology is reflected in the diversity of functions that they perform within the cell. Alterations or imbalances in any of these cellular processes can cause mitochondrial dysfunction and dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f321e7ab2b9247531f2584660209ba7c
https://doi.org/10.1007/978-3-030-70147-5_10
https://doi.org/10.1007/978-3-030-70147-5_10
Autor:
Alberto Sanz, Rhoda Stefanatos, Ashwin Sriram, L. Miguel Martins, Samantha H. Y. Loh, Filippo Scialò, Ruth V. Spriggs
Publikováno v:
Redox Biology, Vol 32, Iss, Pp-(2020)
Redox Biology
Redox Biology
Reactive Oxygen Species (ROS) are essential cellular messengers required for cellular homeostasis and regulate the lifespan of several animal species. The main site of ROS production is the mitochondrion, and within it, respiratory complex I (CI) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355a4647b7e902119ec5116f04eecb15
http://www.sciencedirect.com/science/article/pii/S2213231719314600
http://www.sciencedirect.com/science/article/pii/S2213231719314600