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of 131
pro vyhledávání: '"RhoGEF domain"'
Akademický článek
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Publikováno v:
PeerJ, Vol 7, p e7025 (2019)
PeerJ
PeerJ
BackgroundGastric cancer (GC) is the third leading cause of cancer-related death worldwide, partially due to the lack of effective screening strategies. Thus, there is a stringent need for non-invasive biomarkers to improve patient diagnostic efficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7dc23830465ccad7de56fdc9560ced
https://peerj.com/articles/7025/
https://peerj.com/articles/7025/
Autor:
Dong Yan, Norbert Perrimon, Tony J. C. Harris, Sérgio Simões, Yan Li, Jordan T. Silver, Milena Pellikka, Frederik Wirtz-Peitz, Richard Binari, Ulrich Tepass, Takashi Nishimura
The spatio-temporal regulation of small Rho GTPases is crucial for the dynamic stability of epithelial tissues. However, how RhoGTPase activity is controlled during development remains largely unknown. To explore the regulation of Rho GTPases in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2e49f07019b21da35b05aea0883334
Autor:
Tzu-Ting Chiou, Philip Long, Alexandra Schumann-Gillett, Venkateswarlu Kanamarlapudi, Stefan A. Haas, Kirsten Harvey, Megan L. O’Mara, Angel L. De Blas, Vera M. Kalscheuer, Robert J. Harvey
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Frontiers in Molecular Neuroscience, Vol 12 (2019)
The recruitment of inhibitory GABAA receptors to neuronal synapses requires a complex interplay between receptors, neuroligins, the scaffolding protein gephyrin and the GDP-GTP exchange factor collybistin (CB). Collybistin is regulated by protein-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a74ff63ec4cebe360c1fc46b2ac8404
https://hdl.handle.net/21.11116/0000-0006-09F8-921.11116/0000-0006-09FA-7
https://hdl.handle.net/21.11116/0000-0006-09F8-921.11116/0000-0006-09FA-7
Autor:
Cha Yeon Kim, Trang T. T. Nguyen, Won Do Heo, Wei Sun Park, Taeyoon Kyung, Tobias Meyer, Klaus M. Hahn, Yohan Oh, Byung Ouk Park, Gabsang Lee, Hana Choi, Jin Man Kim, Cheol-Hee Kim
Publikováno v:
Proceedings of the National Academy of Sciences. 113:10091-10096
Cells migrate by directing Ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division control protein 42 (Cdc42) activities and by polymerizing actin toward the leading edge of the cell. Previous studies have proposed that this polarization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132d1eb8b16000a2116e1a24ab23640c
https://doi.org/10.1073/pnas.1604720113
https://doi.org/10.1073/pnas.1604720113
Publikováno v:
Leukemia Research. 97:106440
Expression of the p210 BCR/ABL1 fusion protein has been described in virtually all patients with chronic myelogenous leukemia (CML). Previous studies have identified a guanine nucleotide exchange factor (RhoGEF) domain within BCR that is retained in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c32abe84f36d89cd2bb0c93e19dfb85
https://doi.org/10.1016/j.leukres.2020.106440
https://doi.org/10.1016/j.leukres.2020.106440
Publikováno v:
Current Biology. 30:1477-1490.e3
How septin architecture is remodeled from an hourglass to a double ring during cytokinesis in fungal and animal cells remains unknown. Here, we show that during the hourglass-to-double ring transition in budding yeast, septins acquire a striking “z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2852201b94889d67a5ac5ee931a221e
https://doi.org/10.1016/j.cub.2020.02.023
https://doi.org/10.1016/j.cub.2020.02.023
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Publikováno v:
The Journal of biological chemistry. 292(51)
RUN and FYVE domain–containing 3 (Rufy3) is an adapter protein for small GTPase proteins and is bound to activated Rap2, a Ras family protein in the developing neuron. Previously, we reported the presence of a rapid cell polarity determination mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd07a09a413c3d85f0df0a08ef2599d
https://pubmed.ncbi.nlm.nih.gov/29089386
https://pubmed.ncbi.nlm.nih.gov/29089386
Autor:
A Tellermann, Torsten Witte, C. Lansche, Reinhold E. Schmidt, N.T. Baerlecken, Matthias Stoll
Publikováno v:
HIV Medicine. 16:114-121
Objectives The diagnosis of extrapulmonary tuberculous infections and nontuberculous mycobacterial (NTM) infections is difficult because the symptoms are nonspecific and suitable specimens for bacterial culture are often not available. Recent publica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fbc236272925d2f13135b5928da87ea
https://doi.org/10.1111/hiv.12194
https://doi.org/10.1111/hiv.12194