Rho-inhibition and neuroprotective effect on rotenone-treated dopaminergic neurons in vitro

Autor: Mattii, Letizia ^{a, d}, Pardini, Carla ^b, Ippolito, Chiara ^a, Bianchi, Francesco ^a, Sabbatini, Antonietta Raffaella Maria ^c, Vaglini, Francesca ^{b, ⁎}

Publikováno v: In Neurotoxicology May 2019 72:51-60

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Systematic review and stratified meta-analysis of the efficacy of RhoA and Rho kinase inhibitors in animal models of ischaemic stroke

Autor: Hanna M. Vesterinen, Malcolm R. Macleod, Kieren J. Egan, Ralf Watzlawick, Gillian L. Currie, Sarah Mee, Samantha Carter, Emily S. Sena

Publikováno v: Vesterinen, H M, Currie, G L, Carter, S, Mee, S, Watzlawick, R, Egan, K J, Macleod, M R & Sena, E S 2013, ' Systematic review and stratified meta-analysis of the efficacy of RhoA and Rho kinase inhibitors in animal models of ischaemic stroke ', Systematic Reviews, vol. 2, no. 1, pp. 33 . https://doi.org/10.1186/2046-4053-2-33
Systematic Reviews

Background There is currently only one clinically approved drug, tissue plasminogen activator (tPA), for the treatment of acute ischaemic stroke. The RhoA pathway, including RhoA and its downstream effector Rho kinase (ROCK), has been identified as a

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