Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Rho kinase (ROCK)"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Daniel A. Linseman, Qun Lu
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/0e5d48f5965b40c689db75b2a081051d
Autor:
Tong Liu, Ning Zhang, Lingya Kong, Sijie Chu, Ting Zhang, Guangdi Yan, Donglai Ma, Jun Dai, Zhihong Ma
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Paeoniflorin (PF) is the main active component in Paeonia lactiflora Pall, and it has multiple effects. However, the precise mechanism of PF in hypercholesterolemia is unclear. In this study, rats were either fed a high-cholesterol diet (HCD) for 4 w
Externí odkaz:
https://doaj.org/article/5dc547652e38400da1135e65b825afb0
Autor:
Keiichiro Matoba, Kensuke Sekiguchi, Yosuke Nagai, Yusuke Takeda, Hiroshi Takahashi, Tamotsu Yokota, Kazunori Utsunomiya, Rimei Nishimura
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Rho-associated coiled-coil-containing protein kinase (ROCK) is a serine/threonine kinase with essential roles in cytoskeletal functions. Substantial evidence implicates ROCK as a critical regulator in the inception and progression of diabetic nephrop
Externí odkaz:
https://doaj.org/article/8adbfd3744e147d883a9457dcd886bc8
Autor:
Vitor R. Muñoz, Rafael C. Gaspar, Matheus B. Severino, Ana P. A. Macêdo, Fernando M. Simabuco, Eduardo R. Ropelle, Dennys E. Cintra, Adelino S. R. da Silva, Young-Bum Kim, José Rodrigo Pauli
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Physical exercise is considered a fundamental strategy in improving insulin sensitivity and glucose uptake in skeletal muscle. However, the molecular mechanisms underlying this regulation, primarily on skeletal muscle glucose uptake, are not fully un
Externí odkaz:
https://doaj.org/article/e425139095d144638760cc70c4c41a0e
Autor:
Zhanting Yang, Haixia Sun, Shanshan Su, Xingmei Nan, Ke Li, Xueqin Jin, Guoen Jin, Zhanqiang Li, Dianxiang Lu
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Background: Tsantan Sumtang originated from Four Tantras, which consisted of Choerospondias axillaris (Roxb.) B. L. Burtt and A. W. Hill, Santalum album L., and Myristica fragrans Houtt. The three herbs are in ratio 1:1:1. This medication is widely u
Externí odkaz:
https://doaj.org/article/3ecc40164db346edb5f5e9cef40ad089
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10416
The amyloidogenic processing of APP depends on two events: its phosphorylation by ROCK2 (at Thr654) and the phosphorylation of the APP-cleaving enzyme BACE1 (at Ser498). However, the mechanisms and structural details of APP-ROCK2 and BACE1-ROCK2 bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::123f23526d2ce517b92d8a7ce8172a68
Publikováno v:
Stem Cell Reports, Vol 6, Iss 5, Pp 743-756 (2016)
In this study we dissected retinal organoid morphogenesis in human embryonic stem cell (hESC)-derived cultures and established a convenient method for isolating large quantities of retinal organoids for modeling human retinal development and disease.
Externí odkaz:
https://doaj.org/article/501fd9cd47104c5191fd7fabfa9eeabb
Autor:
Marianna Ranieri, Maria Venneri, Tommaso Pellegrino, Mariangela Centrone, Annarita Di Mise, Susanna Cotecchia, Grazia Tamma, Giovanna Valenti
Publikováno v:
Cells, Vol 9, Iss 6, p 1354 (2020)
NSIAD is a rare X-linked condition, caused by activating mutations in the AVPR2 gene coding for the vasopressin V2 receptor (V2R) associated with hyponatremia, despite undetectable plasma vasopressin levels. We have recently provided in vitro evidenc
Externí odkaz:
https://doaj.org/article/cf566a371338486dacacf4854613cd8d