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Akademický článek

Induction of Fatty Acid Oxidation Underlies DNA Damage‐Induced Cell Death and Ameliorates Obesity‐Driven Chemoresistance

Autor: Sunsook Hwang, Seungyeon Yang, Kyungsoo Park, Byungjoo Kim, Minjoong Kim, Seungmin Shin, Ahyoung Yoo, Jiyun Ahn, Juneil Jang, Yeong Shin Yim, Rho H. Seong, Seung Min Jeong

Publikováno v: Advanced Science, Vol 11, Iss 10, Pp n/a-n/a (2024)

Abstract The DNA damage response is essential for preserving genome integrity and eliminating damaged cells. Although cellular metabolism plays a central role in cell fate decision between proliferation, survival, or death, the metabolic response to

Externí odkaz: https://doaj.org/article/b182c5a25c4547a98f407647ac2477bf

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Akademický článek

PRDM16 regulates γδT17 cell differentiation via controlling type 17 program and lipid-dependent cell fitness

Autor: Jinwoo Nah, Youngjin Lee, Rho H. Seong

Publikováno v: Frontiers in Immunology, Vol 14 (2024)

γδT17 cells are a subset of γδT cells producing IL-17, which is crucial for protection against bacterial and fungal infections. It has recently been shown that γδT17 cells have enriched lipid storage and lipid metabolism. However, the regulatio

Externí odkaz: https://doaj.org/article/497b3e2e12c2463e9dc9f384dc5bea98

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