Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Rhishikesh Thakare"'
Autor:
John A. Bowden, Alan Heckert, Candice Z. Ulmer, Christina M. Jones, Jeremy P. Koelmel, Laila Abdullah, Linda Ahonen, Yazen Alnouti, Aaron M. Armando, John M. Asara, Takeshi Bamba, John R. Barr, Jonas Bergquist, Christoph H. Borchers, Joost Brandsma, Susanne B. Breitkopf, Tomas Cajka, Amaury Cazenave-Gassiot, Antonio Checa, Michelle A. Cinel, Romain A. Colas, Serge Cremers, Edward A. Dennis, James E. Evans, Alexander Fauland, Oliver Fiehn, Michael S. Gardner, Timothy J. Garrett, Katherine H. Gotlinger, Jun Han, Yingying Huang, Aveline Huipeng Neo, Tuulia Hyötyläinen, Yoshihiro Izumi, Hongfeng Jiang, Houli Jiang, Jiang Jiang, Maureen Kachman, Reiko Kiyonami, Kristaps Klavins, Christian Klose, Harald C. Köfeler, Johan Kolmert, Therese Koal, Grielof Koster, Zsuzsanna Kuklenyik, Irwin J. Kurland, Michael Leadley, Karen Lin, Krishna Rao Maddipati, Danielle McDougall, Peter J. Meikle, Natalie A. Mellett, Cian Monnin, M. Arthur Moseley, Renu Nandakumar, Matej Oresic, Rainey Patterson, David Peake, Jason S. Pierce, Martin Post, Anthony D. Postle, Rebecca Pugh, Yunping Qiu, Oswald Quehenberger, Parsram Ramrup, Jon Rees, Barbara Rembiesa, Denis Reynaud, Mary R. Roth, Susanne Sales, Kai Schuhmann, Michal Laniado Schwartzman, Charles N. Serhan, Andrej Shevchenko, Stephen E. Somerville, Lisa St. John-Williams, Michal A. Surma, Hiroaki Takeda, Rhishikesh Thakare, J. Will Thompson, Federico Torta, Alexander Triebl, Martin Trötzmüller, S. J. Kumari Ubhayasekera, Dajana Vuckovic, Jacquelyn M. Weir, Ruth Welti, Markus R. Wenk, Craig E. Wheelock, Libin Yao, Min Yuan, Xueqing Heather Zhao, Senlin Zhou
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 12, Pp 2275-2288 (2017)
As the lipidomics field continues to advance, self-evaluation within the community is critical. Here, we performed an interlaboratory comparison exercise for lipidomics using Standard Reference Material (SRM) 1950–Metabolites in Frozen Human Plasma
Externí odkaz:
https://doaj.org/article/e757670a32e84af9bc9bad52c975b5dc
Autor:
Megan E. Patton, Lauren J. Taylor, Zeynep Madak-Erdogan, Ju Seog Lee, Sung Hwan Lee, Rhishikesh Thakare, Sayeepriyadarshini Anakk, Sherwin H Kelekar, Milton J. Finegold, Yazen Alnouti
Hepatocellular carcinoma (HCC) is the most common liver cancer with a higher incidence in males. Here, we report that the spontaneous HCC development subsequent to the deletion of both Farnesoid X Receptor and Small Heterodimer Partner (DKO) mimics t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::238e41dc14c71604d0cab2b8ecda5e0f
https://doi.org/10.1101/2020.06.25.172635
https://doi.org/10.1101/2020.06.25.172635
Autor:
Nagsen Gautam, Yazen Alnouti, A. David Rodrigues, Jawaher Abdullah Alamoudi, Rhishikesh Thakare
Publikováno v:
Journal of Applied Toxicology. 38:1336-1352
One of the mechanisms of drug-induced liver injury (DILI) involves alterations in bile acid (BA) homeostasis and elimination, which encompass several metabolic pathways including hydroxylation, amidation, sulfation, glucuronidation and glutathione co
Autor:
Yazen Alnouti, Jawaher Abdullah Alamoudi, Rhishikesh Thakare, Nagsen Gautam, A. David Rodrigues
Publikováno v:
Journal of Applied Toxicology. 38:1323-1335
Maintenance of bile acid (BA) homeostasis is essential to achieve their physiologic functions and avoid their toxic effects. The marked differences in BA composition between preclinical safety models and humans may play a major role in the poor predi
Autor:
Jing Wang, Carter J. Barger, Smitha Kizhake, Smit Kour, Michael A. Hollingsworth, Rhishikesh Thakare, Sanjib Chowdhury, Jennifer D. Black, Beth K. Neilsen, Sandeep Rana, Caroline M. Robb, Yogesh A. Sonawane, Michael G. Brattain, Ekta Agarwal, Amarnath Natarajan, Jacob I. Contreras, Margaret A. Taylor
Publikováno v:
Oncotarget
Colorectal cancer (CRC) remains one of the leading causes of cancer related deaths in the United States. Currently, there are limited therapeutic options for patients suffering from CRC, none of which focus on the cell signaling mechanisms controlled
Autor:
Crystal Krause, Rhishikesh Thakare, Jawaher Abdullah Alamoudi, Yazen Alnouti, Rohit Kohli, Melissa C. Helm, Vishal Kothari, Corrigan L. McBride, Dmitry Oleynikov, Tammy L. Kindel
Publikováno v:
Surgical Endoscopy. 32:805-812
Bile acids (BAs) are post-prandial hormones that play an important role in glucose and lipid homeostasis as well as energy expenditure. Total and glycine-amidated BAs increase after sleeve gastrectomy (SG) and correlate to improved metabolic disease.
Autor:
Dinesh A. Barawkar, Siddhartha De, Yogesh Waman, Ashwinkumar V. Meru, Vidya Ramdas, Kasim A. Mookhtiar, Srinivasa B. Reddy, Sumit Chaudhary, Sujay Basu, Santosh Kumar Madadi, Rhishikesh Thakare, Venkata P. Palle, Anita Chugh, Gaurav Bedse, Summon Koul, Srinivas Rao Chennamaneni, Yogesh D. Shejul, Neela Prasad, Sandhya Chaturvedi, Rajesh Bonagiri, Suraj Menon, Jayasagar Gundu
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:1963-1975
Multipronged approach was used to synthesize a library of diverse C-8 cyclopentyl hypoxanthine analogs from a common intermediate III. Several potent and selective compounds were identified and evaluated for pharmacokinetic (PK) properties in Wistar
Autor:
Azfar Quraishi, Anita Chug, Suraj Menon, Vishal Unadkat, Sujay Basu, Madhav S. Seervi, Vandna Prasad, Sumit Chaudhary, Yogesh D. Shejul, Ganesh Bhat, Sachin Thorat, Ravi K. Bhamidipati, Shariq S. Ansari, Ashwinkumar V. Meru, Rhishikesh Thakare, Kasim A. Mookhtiar, Yogesh Salve, Venkata P. Palle, Minakshi Naykodi, Siddhartha De, Vaibhav Jain, Harish Patil, Indraneel Ghosh, Dinesh A. Barawkar, Meena Patel, Sreekanth R. Rouduri
Publikováno v:
Journal of Medicinal Chemistry. 60:681-694
Our initial structure–activity relationship studies on 7-methoxy-4-morpholino-benzothiazole derivatives featured by aryloxy-2-methylpropanamide moieties at the 2-position led to identification of compound 25 as a potent and selective A2A adenosine
Autor:
Cian Monnin, Anthony D. Postle, S. J. Kumari A. Ubhayasekera, Matej Orešič, Tomas Cajka, Jacquelyn M. Weir, Candice Z. Ulmer, Stephen E. Somerville, Xueqing Zhao, Therese Koal, Renu Nandakumar, Senlin Zhou, Denis Reynaud, John A. Bowden, James E. Evans, Joost Brandsma, Rhishikesh Thakare, Jeremy P. Koelmel, Houli Jiang, Tuulia Hyötyläinen, Christoph H. Borchers, Oliver Fiehn, J. Will Thompson, Susanne Sales, Karen Lin, Christina M. Jones, Jun Han, Aveline H. Neo, Laila Abdullah, Charles N. Serhan, Mary R. Roth, Danielle J. McDougall, Alexander Triebl, Martin Trötzmüller, Yazen Alnouti, Serge Cremers, Michelle Cinel, Irwin J. Kurland, Kai Schuhmann, Craig E. Wheelock, Min Yuan, Romain A. Colas, Ruth Welti, Yingying Huang, Hiroaki Takeda, Timothy J. Garrett, Jon Rees, Takeshi Bamba, Grielof Koster, Michal A. Surma, Libin Yao, Natalie A. Mellett, Johan Kolmert, M. Arthur Moseley, Krishna Rao Maddipati, Harald Köfeler, John M. Asara, Dajana Vuckovic, Aaron M. Armando, Michael S. Gardner, Peter J. Meikle, Rebecca S. Pugh, Yoshihiro Izumi, Alexander Fauland, Antonio Checa, Jonas Bergquist, Amaury Cazenave-Gassiot, Parsram Ramrup, Zsuzsanna Kuklenyik, Alan Heckert, Hongfeng Jiang, Yunping Qiu, David A. Peake, Oswald Quehenberger, Markus R. Wenk, John R. Barr, Michael Leadley, Linda Ahonen, Barbara Rembiesa, Jiang Jiang, Martin Post, Kristaps Klavins, Susanne B. Breitkopf, Lisa St. John-Williams, Michal L. Schwartzman, Edward A. Dennis, Andrej Shevchenko, Katherine H. Gotlinger, Federico Torta, Christian Klose, Jason S. Pierce, Rainey E. Patterson, Reiko Kiyonami, Maureen Kachman
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 12, Pp 2275-2288 (2017)
Journal of lipid research, vol 58, iss 12
Journal of lipid research, vol 58, iss 12
As the lipidomics field continues to advance, self-evaluation within the community is critical. Here, we performed an interlaboratory comparison exercise for lipidomics using Standard Reference Material (SRM) 1950-Metabolites in Frozen Human Plasma,
Autor:
Rhishikesh, Thakare, Jawaher Abdullah, Alamoudi, Nagsen, Gautam, A David, Rodrigues, Yazen, Alnouti
Publikováno v:
Journal of applied toxicology : JAT. 38(10)
Maintenance of bile acid (BA) homeostasis is essential to achieve their physiologic functions and avoid their toxic effects. The marked differences in BA composition between preclinical safety models and humans may play a major role in the poor predi