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Concentration-QT modelling in early clinical oncology settings: Simulation evaluation of performance
Autor:
Corina Dota, Rhianna O'Sullivan, Gael Cantet, Alienor Berges, Vincent F. S. Dubois, Guillemette E. Benoist, Stein Schalkwijk, Joanna Parkinson, Dinko Rekić, Sarit Cohen-Rabbie, Helen Tomkinson
Publikováno v:
British journal of clinical pharmacologyREFERENCES. 88(3)
AIMS Concentration-QT modelling (C-QTc) of first-in-human data has been rapidly adopted as the primary evaluation of QTc interval prolongation risk. Here, we evaluate the performance of C-QTc in early oncology settings (i.e., patients, no placebo or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a14135386ec8d82fe62d4fb061bd1e
https://pubmed.ncbi.nlm.nih.gov/34416045
https://pubmed.ncbi.nlm.nih.gov/34416045
