Výsledky vyhledávání - "Rhian S Thomas"

Akademický článek

Upregulation of endocytic protein expression in the Alzheimer’s disease male human brain

Autor: Mouhamed Alsaqati, Rhian S. Thomas, Emma J. Kidd

Publikováno v: Aging Brain, Vol 4, Iss , Pp 100084- (2023)

Amyloid-beta (Aβ) is produced from amyloid precursor protein (APP) primarily after APP is internalised by endocytosis and clathrin-mediated endocytic processes are altered in Alzheimer’s disease (AD). There is also evidence that cholesterol and fl

Externí odkaz: https://doaj.org/article/352a4772479b4f8ba9105e26164a4250

Zobrazit plný text záznamu

Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection

Autor: Duraiswamy Basavan, Suresh Kumar Mohankumar, Deepraj Paul, Chai Boon Kheng, Rhian S Thomas

Publikováno v: Current Drug Targets. 23:364-372

Background: Angiotensin-converting enzyme 2 (ACE2) has been reported as a portal for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Consequently, scientific strategies to combat coronavirus disease of 2019 (COVID-19) were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5669c4057dd7b9396f2c3f723ecc3036
https://doi.org/10.2174/1389450122666211103165837

Zobrazit plný text záznamu

A rapidly acquired foraging-based working memory task, sensitive to hippocampal lesions, reveals age-dependent and age-independent behavioural changes in a mouse model of amyloid pathology

Autor: Charles E. Evans, Rhian S. Thomas, Mark Andrew Good, Martha Hvoslef-Eide, Emma Jane Kidd

Publikováno v: Neurobiology of Learning and Memory. 149:46-57

Three experiments examined the ability of mice to forage efficiently for liquid rewards in pots located in an open field arena. Search behaviour was unconstrained other than by the walls of the arena. All mice acquired the task within 4 days of train

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9219e6da92268752c6f81d53e8f64c13
https://doi.org/10.1016/j.nlm.2018.02.004

Zobrazit plný text záznamu

Alterations in endocytic protein expression with increasing age in the transgenic APP695 V717I London mouse model of amyloid pathology

Autor: Martha Hvoslef-Eide, Rhian S. Thomas, Justin S. Bice, Emma Jane Kidd, Mouhamed Alsaqati, Mark Andrew Good

Publikováno v: NeuroReport. 28:963-968

A major risk factor for the development of Alzheimer's disease (AD) is increasing age, but the reason behind this association has not been identified. It is thought that the changes in endocytosis seen in AD patients are causal for this condition. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a38a254184a0411ed255665d4f0d567
https://doi.org/10.1097/wnr.0000000000000861

Zobrazit plný text záznamu

Proteins Involved in Endocytosis Are Upregulated by Ageing in the Normal Human Brain: Implications for the Development of Alzheimer's Disease

Autor: Rhian S. Thomas, Mouhamed Alsaqati, Emma Jane Kidd

Publikováno v: The journals of gerontology. Series A, Biological sciences and medical sciences. 73(3)

The greatest risk factor for Alzheimer’s disease (AD) is advanced age, but the reason for this association remains unclear. Amyloid-beta (Aβ) is produced from amyloid precursor protein (APP) primarily after APP is internalised by clathrin-mediated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3509e53e22505e20b9f24e745739bf34
https://pubmed.ncbi.nlm.nih.gov/28655199

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání