Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Rheumatology/Systemic Lupus Erythematosos"'
Autor:
Timothy W. Behrens, M. Ilyas Kamboh, Patrick M. Gaffney, Carl D. Langefeld, Ward Ortmann, Sharon A. Chung, Peter K. Gregersen, Betty P. Tsao, John B. Harley, Marta E. Alarcón-Riquelme, Michelle Petri, Chaim O. Jacob, Kathy L. Moser, Kimberly E. Taylor, Susan Manzi, Lindsey A. Criswell, Robert R. Graham, Annette Lee
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 2, p e1001311 (2011)
PLoS Genetics, Vol 7, Iss 2, p e1001311 (2011)
Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous clinical manifestations. Recent studies have greatly expanded the number of established SLE risk alleles, but the distribution of multiple risk alleles in cases ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023768cfbacd50ae7fa0b5476c8b1479
http://europepmc.org/articles/PMC3040652
http://europepmc.org/articles/PMC3040652
Autor:
Reena Kapadia, Joseph M. Baron, Mary Smaron, Anthony Chang, Farzan Mahmood, Suncica Volkov, Deborah Manst, Maria Badaracco, Nadera J. Sweiss, Tara Adhikari, Jerrold S. Levine, Ronghai Bo
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12280 (2010)
PLoS ONE
PLoS ONE
BackgroundThe clinical utility of testing for antiphospholipid antibodies (aPL) of IgA isotype remains controversial.Methodology/principal findingsTo address this issue, we reasoned that if IgA aPL contribute to the clinical manifestations of the ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbad4e87994ee20420b471819a2f76b
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20808864/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20808864/?tool=EBI
Autor:
Sunghoon Kim, Nam Hoon Kwon, Jung Min Han, Seung Jae Jeong, Zihai Li, Hyeong Rae Kim, Hee Jung Jung, Jin Young Lee
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 3, p e9792 (2010)
PLoS ONE, Vol 5, Iss 3, p e9792 (2010)
Heat shock proteins have been implicated as endogenous activators for dendritic cells (DCs). Chronic expression of heat shock protein gp96 on cell surfaces induces significant DC activations and systemic lupus erythematosus (SLE)-like phenotypes in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eecf424014b830a372fb7a9cc82a217
http://europepmc.org/articles/PMC2843739
http://europepmc.org/articles/PMC2843739
Autor:
Clifford Qualls, Carlos A. Roldan, Rex E. Jung, Rachael G. Grazioplene, Wilmer L. Sibbitt, Judith M. Segall
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9302 (2010)
PLoS ONE
PLoS ONE
Within systemic lupus erythematosus (SLE) patients can be divided into groups with and without central nervous system involvement, the latter being subcategorized as neuropsychiatric systemic lupus erythematosus (NPSLE). While a number of research gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd5b5adbe45f11b4e8e7ca69e046ebc
http://europepmc.org/articles/PMC2844408?pdf=render
http://europepmc.org/articles/PMC2844408?pdf=render
Autor:
Qiji Liu, Irene Oi-Lin Ng, Pak C. Sham, Nattiya Hirankarn, Ruo-Jie Li, Marco Ho, Yingyos Avihingsanon, Yan Zhang, Chak Sing Lau, Tsz Leung Lee, Wilfred Hing Sang Wong, Chi Chiu Mok, Philip H. Li, Wanling Yang, Pamela Pui Wah Lee, Xiang-Pei Li, Xiaoxia Qian, Dong-Qing Ye, Chun-Ming Wong, Alexander Moon Ho Leung, Lu Zhang, Mo Yin Mok, Sik Nin Wong, Raymond Woon Sing Wong, Hai-Feng Pan, Yuk Kwan Chang, Tak Mao Chan, Nan Shen, Dingge Ying, KW Lee, Yu-Lung Lau
Publikováno v:
PLoS Genetics, Vol 6, Iss 2, p e1000841 (2010)
PLoS Genetics
PLoS Genetics
Systemic lupus erythematosus is a complex and potentially fatal autoimmune disease, characterized by autoantibody production and multi-organ damage. By a genome-wide association study (320 patients and 1,500 controls) and subsequent replication altog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa3188920b5b4a7aafab5723d088a3a
http://europepmc.org/articles/PMC2820522?pdf=render
http://europepmc.org/articles/PMC2820522?pdf=render
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11124 (2010)
PLoS ONE
PLoS ONE
Background Neuropsychiatric systemic lupus erythematosus (NPSLE) is a major complication for lupus patients, which often leads to cognitive disturbances and memory loss and contributes to a significant patient morbidity and mortality. The presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0c2d304fcc312b0e192397edbe5161
http://europepmc.org/articles/PMC2886066?pdf=render
http://europepmc.org/articles/PMC2886066?pdf=render
Autor:
Takeshi Azuma, Eric L. Matteson, Charles G. Drake, Gefeng Zhu, Haiying Xu, Cecilia Rietz, Lieping Chen
Publikováno v:
PLoS Medicine, Vol 6, Iss 10, p e1000166 (2009)
PLoS Medicine
PLoS Medicine
Finding an association between soluble B7-H4 and rheumatoid arthritis severity, Lieping Chen and colleagues use a mouse model to show that the soluble form blocks the inhibitory function of cell-surface B7-H4.
Background A pathogenic hallmark of
Background A pathogenic hallmark of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367a57c11607958578fa56565c91d6bc
http://europepmc.org/articles/PMC2760136?pdf=render
http://europepmc.org/articles/PMC2760136?pdf=render
Autor:
Sharon A. Chung, Diana L. Quach, Kimberly E. Taylor, Patricia P. Ramsay, Timothy W. Behrens, Julie A. Lane, John B. Harley, Jennifer A. Kelly, Michael F. Seldin, Patrick M. Gaffney, Joanne Nititham, Lindsey A. Criswell, Janelle A. Noble, Glenys Thomson, Lisa F. Barcellos, Kathy L. Moser, Suzanne L. May, Hong L. Quach
Publikováno v:
PLoS Genetics, Vol 5, Iss 10, p e1000696 (2009)
PLoS genetics, vol 5, iss 10
PLoS Genetics
PLoS genetics, vol 5, iss 10
PLoS Genetics
A substantial genetic contribution to systemic lupus erythematosus (SLE) risk is conferred by major histocompatibility complex (MHC) gene(s) on chromosome 6p21. Previous studies in SLE have lacked statistical power and genetic resolution to fully def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5235801759f3da88240b691f322454
http://europepmc.org/articles/PMC2758598?pdf=render
http://europepmc.org/articles/PMC2758598?pdf=render
Autor:
Jean-Marc Strub, Nicolas Schall, Jean-Paul Briand, Alain Van Dorsselaer, Manh Thong Cung, Sylviane Muller, Nicolas Page, Marion Decossas, Marc Quinternet, Olivier Chaloin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 4, p e5273 (2009)
PLoS ONE, Public Library of Science, 2009, 4 (4), pp.e5273. ⟨10.1371/journal.pone.0005273⟩
PLoS ONE, Vol 4, Iss 4, p e5273 (2009)
PLoS ONE, Public Library of Science, 2009, 4 (4), pp.e5273. ⟨10.1371/journal.pone.0005273⟩
International audience; The phosphopeptide P140 issued from the spliceosomal U1-70K snRNP protein is recognized by lupus CD4(+) T cells, transiently abolishes T cell reactivity to other spliceosomal peptides in P140-treated MRL/lpr mice, and ameliora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a826fc4fac06a3baa9fc40718d5762fe
http://europepmc.org/articles/PMC2669294
http://europepmc.org/articles/PMC2669294
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6098 (2009)
PLoS ONE
PLoS ONE
Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease with a complex spectrum of cellular and molecular characteristics including several dramatic changes in the populations of peripheral leukocytes. These changes include general leukop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee25f611ed174d0608d46a1981078b9
http://europepmc.org/articles/PMC2699551?pdf=render
http://europepmc.org/articles/PMC2699551?pdf=render