Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Rheumatic Disease/Vasculitis"'
Autor:
Harvey Cantor, Georg F. Weber
Publikováno v:
Clinical and Experimental Immunology. 126:578-583
SummaryThe cytokine osteopontin (Eta-1) leads to macrophage-dependent polyclonal B-cell activation and is induced early in autoimmune prone mice with the lpr mutation, suggesting a significant pathogenic role for this molecule. Indeed, C57BL/6-Faslpr
Publikováno v:
Clinical and Experimental Immunology. 126:560-569
SummaryPolyarthritis may result from the haematogenous distribution of arthritogenic effector lymphocytes that emerge in the efferent lymph and pass through the thoracic duct (TD) to the circulation. We therefore examined whether TD cells collected f
Publikováno v:
Clinical and Experimental Immunology. 126:345-354
SummaryIn order to elucidate the immunological properties of anti-U1-ribonucleoprotein (RNP) antibody, one of the autoantibodies detected in patients with connective tissue diseases (CTDs), we tested the endothelial cell-binding by anti-U1-RNP antibo
Autor:
Masataka Kuwana, Norihito Yazawa, Masahide Kubo, Hironobu Ihn, Kunihiko Tamaki, Kenichi Yamane
Publikováno v:
Clinical and Experimental Immunology. 126:339-344
SummaryNew antibodies against a U3 snRNP, which were named anti-Myo 22/25 antibodies, were detected in four (8%) of 53 serum samples from patients with polymyositis/dermatomyositis (PM/DM) by RNA immunoprecipitation. In the protein immunoprecipitatio
Autor:
G. Tonietti, A Fulminis, G Barattelli, G Cifone, Marco Matucci-Cerinic, Paola Cipriani, Roberto Giacomelli, S D'Alò
Publikováno v:
Clinical and Experimental Immunology. 125:310-315
Systemic sclerosis (SSc) is a connective tissue disease in which immune system activation is evidenced by high levels of different cytokines in the sera and/or in the supernatants of cultured peripheral blood mononuclear cells (PBMC) and by the prese
Publikováno v:
Clinical and Experimental Immunology. 125:332-339
SummaryWegener's granulomatosis initially affects upper respiratory tract organs including the nasal mucosa in more than 90% of patients. The inflammation is typically granulomatous with associated vasculitis. T lymphocytes are usually a prominent co
Autor:
C. Myers, Ralph C. Williams, Elena Csernok, R. Staud, C C Malone, Wolfgang L. Gross, Ammon B. Peck, E. Peen
Publikováno v:
Clinical and Experimental Immunology. 125:323-331
SummaryAmphipathic variable-region heavy chain 11-mer peptides from monoclonal human IgM antiproteinase-3 antibodies were studied for peripheral blood lymphocyte stimulation in 21 patients with Wegener's granulomatosis (WG) or microscopic polyangiiti
Publikováno v:
Clinical and Experimental Immunology. 125:316-322
SummaryA previous case report described the formation of a complex between a monoclonal IgA with cryolabile properties and C-reactive protein (CRP). Our study provides the first evidence for the frequent occurrence of CRP in cryoglobulins (Cg) of all
Autor:
Hidero Kitasato, M. Rana, Toshimichi Matsui, Hirahito Endo, Tohru Akahoshi, K. Takagishi, Hirobumi Kondo, Akito Nishimura, A. Hashimoto, Y. Kurihara, Rie Namai, Shinichi Kawai
Publikováno v:
Clinical and Experimental Immunology. 125:155-161
Infiltration of various types of leucocytes has been shown to play a crucial role in the pathogenesis of rheumatoid arthritis (RA). Macrophage inflammatory protein-3 alpha (MIP-3 alpha) is a recently identified chemokine which is a selective chemoatt
Publikováno v:
Clinical and Experimental Immunology. 125:162-168
SummaryRo ribonucleoproteins (RNPs) are autoantigens that result from the association of a 60-kDa protein (Ro60) with a small RNA (hY1, hY3, hY4 or hY5 in humans, mY1 or mY3 in mice). Previous studies localized Ro RNPs to the cytoplasm. Because Ro RN