Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rhett J. Michelson"'
Publikováno v:
Annual Review of Genetics. 36:617-656
▪ Abstract DNA checkpoints play a significant role in cancer pathology, perhaps most notably in maintaining genome stability. This review summarizes the genetic and molecular mechanisms of checkpoint activation in response to DNA damage. The major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2aba3eff8153fac17b9be7ec018f659
https://doi.org/10.1146/annurev.genet.36.060402.113540
https://doi.org/10.1146/annurev.genet.36.060402.113540
Autor:
Ted Weinert, Rhett J. Michelson
Publikováno v:
BioEssays. 22:966-969
Summary As recently as six years ago, three human diseases with similar phenotypes were mistakenly believed to be caused by a single genetic defect. The three diseases, Ataxia-telangiectasia, Nijmegen breakage syndrome, and an AT-like disorder are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c807052826c936f7233264f5b5082f5f
https://doi.org/10.1002/1521-1878(200011)22:11<966::aid-bies2>3.0.co
https://doi.org/10.1002/1521-1878(200011)22:11<966::aid-bies2>3.0.co
Autor:
Charles W. Putnam, Elizabeth J. Little, Ted Weinert, Lisa Shanks, Rhett J. Michelson, P. Sundareshan, R. Gardner, Kara A. Nyberg, Anthony A. Admire
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 65:433-442
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ead2591add4c1fa3aaceda3ba932f2
https://doi.org/10.1101/sqb.2000.65.433
https://doi.org/10.1101/sqb.2000.65.433
Autor:
Michael W. Collard, Jodi I. Huggenvik, Jim Persinger, Rhett J. Michelson, Amy J. Ziemba, Blaine Bartholomew
Publikováno v:
Journal of Biological Chemistry. 274:30510-30519
Nuclear DEAF-1-related (NUDR) protein is a novel transcriptional regulator with sequence similarity to developmental and oncogenic proteins. NUDR protein deletions were used to localize the DNA binding domain between amino acids 167 and 368, and site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc71eaa311e9b946e6afec515fc971d2
https://doi.org/10.1074/jbc.274.43.30510
https://doi.org/10.1074/jbc.274.43.30510
Autor:
Ted Weinert, Rhett J. Michelson
Publikováno v:
Nature Cell Biology. 1:E177-E179
DNA damage activates a set of proteins whose job is to delay the cell cycle until the damage is repaired. This process was thought to involve the detection of damage by sensor proteins, which transmit a signal to a key protein kinase and thence to do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84c9ea70b7ed7fe5e35aeb82babef4ea
https://doi.org/10.1038/15614
https://doi.org/10.1038/15614
Telomeres are complex structures that serve to protect chromosome ends. Here we provide evidence that in Saccharomyces cerevisiae telomeres may contain an anticheckpoint activity that prevents chromosome ends from signaling cell cycle arrest. We foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e98527d352a5fd4e0d5d381f9992707
https://europepmc.org/articles/PMC1276729/
https://europepmc.org/articles/PMC1276729/
Autor:
Michael W. Collard, Rhett J. Michelson, Kerri A. Mowen, Jodi I. Huggenvik, Amy J. Ziemba, Paul Gurley
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 12(10)
A monkey kidney cDNA that encodes a nuclear regulatory factor was identified by expression and affinity binding to a synthetic retinoic acid response element (RARE) and was used to isolate human placental and rat germ cell cDNAs by hybridization. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af91cb36eac4f36ab2e71e7bd351f646
https://pubmed.ncbi.nlm.nih.gov/9773984
https://pubmed.ncbi.nlm.nih.gov/9773984