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pro vyhledávání: '"Rhese Thompson"'
Autor:
Rhese Thompson, Derek Carbaugh, Joshua Nielsen, Ciara Witt, Rita Meganck, Atul Rangadurai, Bo Zhao, Jeffrey Bonin, Nathan Nicely, William Marzluff, Aaron Frank, Helen Lazear, Qi Zhang
Biomolecules continually sample alternative conformations. Consequently, even the most energetically favored ground conformational state has a finite lifetime. Here, we show that, in addition to the 3D structure, the lifetime of a ground conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a9bc7a269dee4ab11e8d2994cbbea3e
https://doi.org/10.21203/rs.3.rs-2879957/v1
https://doi.org/10.21203/rs.3.rs-2879957/v1
Autor:
Rhese Thompson, Anupriya Agarwal, Jack W. Singer, Ujwal Shinde, Shawn Mahmood, Monika A. Davare, Brian J. Druker, Megan M. Cleary, Johannes Elferich, Steve Kurtz
Publikováno v:
Blood. 126:570-570
Background: A momentous challenge in the treatment of acute myeloid leukemia (AML) is the significant molecular heterogeneity in driving abnormalities and rapid emergence of resistance. Successful clinical translation of novel targeted agents has bee