MOLECULAR NETWORKING-BASED DEREPLICATION OF AMBUIC ACID DERIVATIVES FROM THE MARINE FUNGUS PESTALOTIOPSIS SP. 4A11

Autor: Márcio Luis Andrade e Silva, Sabrina Ketrin Targanski, Patrícia Mendonça Pauletti, Ana Helena Januário, Marcos Antônio Soares, Luis Claudio Kellner Filho, Aline O. dos Santos, Rhenner Ávila Assis, Gustavo Muniz Dias, Hector H. F. Koolen, Wilson Roberto Cunha, Célio F. F. Angolini, Kátia Aparecida de Siqueira, Felipe M. A. da Silva, Lívia Soman de Medeiros

Publikováno v: Química Nova v.45 n.3 2022
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Volume: 45, Issue: 3, Pages: 268-274, Published: 20 MAY 2022

Ambuic acid (AA) is a highly-modified cyclohexenone and known as a promising inhibitor of quorum sensing in methicillinresistant Staphylococcus aureus, and is thus a candidate as an antivirulence drug. This molecule is mainly produced by the species

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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000300268