KRAS ^{G 12C} -inhibitor-based combination therapies for pancreatic cancer: insights from drug screening.

Autor: Tapia Contreras C; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany., Falke JD; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany., Seifert DM; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany., Schneider C; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany., Krauß L; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany., Fang X; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany., Müller D; Institute of Pathology, University Medical Center, Göttingen, Germany., Demirdizen E; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany., Spitzner M; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany., De Oliveira T; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany., Schneeweis C; Institute for Translational Cancer Research and Experimental Cancer Therapy, Technical University Munich, Germany., Gaedcke J; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany.; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany., Kaulfuß S; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; Institute of Human Genetics, University Medical Center Göttingen, Germany., Mirzakhani K; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; Institute of Human Genetics, University Medical Center Göttingen, Germany., Wollnik B; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; Institute of Human Genetics, University Medical Center Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Germany., Conrads K; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; Department of Medical Bioinformatics, University Medical Center Göttingen, Germany., Beißbarth T; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; Department of Medical Bioinformatics, University Medical Center Göttingen, Germany.; CCC-N (Comprehensive Cancer Center Lower Saxony), Göttingen, Germany.; Campus-Institute Data Science (CIDAS), Göttingen, Germany., Salinas G; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; NGS Integrative Genomics Core Unit (NIG), University Medical Center Göttingen (UMG), Germany., Hügel J; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; Department of Medical Informatics, University Medical Center, Göttingen, Germany., Beyer N; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; Department of Medical Informatics, University Medical Center, Göttingen, Germany., Rheinländer S; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; Department of Medical Informatics, University Medical Center, Göttingen, Germany., Sax U; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; Campus-Institute Data Science (CIDAS), Göttingen, Germany.; Department of Medical Informatics, University Medical Center, Göttingen, Germany., Wirth M; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany.; Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany., Conradi LC; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany.; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; CCC-N (Comprehensive Cancer Center Lower Saxony), Göttingen, Germany., Reichert M; Medical Clinic and Polyclinic II, Klinikum rechts der Isar, Technical University Munich, Germany.; Translational Pancreatic Research Cancer Center, Medical Clinic and Polyclinic II, Klinikum rechts der Isar, Technical University Munich, Germany.; Center for Protein Assemblies (CPA), Technical University of Munich, Garching, Germany.; Center for Organoid Systems and Tissue Engineering (COS), Technical University Munich, Garching, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, a Partnership Between DKFZ and University Hospital Klinikum rechts der Isar, Munich, Germany., Ellenrieder V; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; CCC-N (Comprehensive Cancer Center Lower Saxony), Göttingen, Germany.; Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Germany., Ströbel P; Institute of Pathology, University Medical Center, Göttingen, Germany.; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; CCC-N (Comprehensive Cancer Center Lower Saxony), Göttingen, Germany., Ghadimi M; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany.; CCC-N (Comprehensive Cancer Center Lower Saxony), Göttingen, Germany., Grade M; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany.; CCC-N (Comprehensive Cancer Center Lower Saxony), Göttingen, Germany., Saur D; Institute for Translational Cancer Research and Experimental Cancer Therapy, Technical University Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, a Partnership Between DKFZ and University Hospital Klinikum rechts der Isar, Munich, Germany., Hessmann E; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; CCC-N (Comprehensive Cancer Center Lower Saxony), Göttingen, Germany.; Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Germany., Schneider G; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Germany.; Institute for Translational Cancer Research and Experimental Cancer Therapy, Technical University Munich, Germany.; Clinical Research Unit 5002, KFO5002, University Medical Center Göttingen, Germany.; CCC-N (Comprehensive Cancer Center Lower Saxony), Göttingen, Germany.

Publikováno v: Molecular oncology [Mol Oncol] 2024 Sep 10. Date of Electronic Publication: 2024 Sep 10.

Menoci: lightweight extensible web portal enhancing data management for biomedical research projects

Autor: Suhr, M., Lehmann, C., Bauer, C. R., Bender, T., Knopp, C., Freckmann, L., Öst Hansen, B., Henke, C., Aschenbrandt, G., Kühlborn, L. K., Rheinländer, S., Weber, L., Marzec, B., Hellkamp, M., Wieder, P., Sax, U., Kusch, H., Nussbeck, S. Y.

Publikováno v: BMC Bioinformatics, Vol 21, Iss 1, Pp 1-21 (2020)
BMC Bioinformatics

Background Biomedical research projects deal with data management requirements from multiple sources like funding agencies’ guidelines, publisher policies, discipline best practices, and their own users’ needs. We describe functional and quality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::118540888845f52eb3b090395ccd6936
https://doaj.org/article/f7368210085d4f4e8aa1fdef064325a9

Management of Metadata Types in Basic Cardiological Research.

Autor: Kusch H; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany., Kossen R; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Suhr M; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Freckmann L; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Weber L; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Henke C; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Lehmann C; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Rheinländer S; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Aschenbrandt G; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Kühlborn LK; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Marzec B; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Menzel J; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany.; Department of Molecular Biology, UMG, Göttingen, Germany., Schwappach B; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.; Department of Molecular Biology, UMG, Göttingen, Germany., Zelarayán LC; Institute of Pharmacology and Toxicology, UMG, Göttingen, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Göttingen, Göttingen, Germany., Cyganek L; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Göttingen, Göttingen, Germany.; Heart Research Center Göttingen, Clinic for Cardiology and Pneumology, UMG, Göttingen, Germany., Antonios G; Heart Research Center Göttingen, Clinic for Cardiology and Pneumology, UMG, Göttingen, Germany., Kohl T; Heart Research Center Göttingen, Clinic for Cardiology and Pneumology, UMG, Göttingen, Germany., Lehnart SE; German Center for Cardiovascular Research (DZHK), Partner Site Göttingen, Göttingen, Germany.; Heart Research Center Göttingen, Clinic for Cardiology and Pneumology, UMG, Göttingen, Germany., Zoremba M; Institute of Pharmacology and Toxicology, UMG, Göttingen, Germany., Sax U; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany., Nussbeck SY; Department of Medical Informatics, University Medical Center Göttingen (UMG), Göttingen, Germany.; Central Biobank UMG, UMG, Göttingen, Germany.

Publikováno v: Studies in health technology and informatics [Stud Health Technol Inform] 2021 Sep 21; Vol. 283, pp. 59-68.

Endothelin receptor-antagonists suppress lipopolysaccharide-induced cytokine release from alveolar macrophages of non-smokers, smokers and COPD subjects.

Autor: Gerlach K; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Köhler-Bachmann S; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Jungck D; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Körber S; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Yanik S; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Knoop H; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Wehde D; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Rheinländer S; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Walther JW; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Kronsbein J; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany., Knobloch J; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany. Electronic address: juergen.knobloch@ruhr-uni-bochum.de., Koch A; Department of Internal Medicine III for Pneumology, Allergology, Sleep- and Respiratory Medicine, University Hospital Bergmannsheil, Bochum, Germany. Electronic address: andrea.koch@bergmannsheil.de.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2015 Dec 05; Vol. 768, pp. 123-30. Date of Electronic Publication: 2015 Oct 23.

Pt Decorated Ni−Ni(OH)2 Nanotube Arrays for Efficient Hydrogen Evolution Reaction.

Autor: Li, Dandan¹ (AUTHOR), Liu, Fengyu² (AUTHOR), Dou, Jianmin¹ (AUTHOR), Zhao, Qiang³ (AUTHOR) zhaoqiang@tyut.edu.cn

Publikováno v: ChemCatChem. 12/15/2021, Vol. 13 Issue 24, p5078-5083. 6p.