Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rhea Kataria"'
Autor:
Satoshi Kubo, Rhea Kataria, Yikun Yao, Justin Q. Gabrielski, Lixin Zheng, Tovah E. Markowitz, Waipan Chan, Jian Song, Arun K. Boddapati, Keita Saeki, Björn Häupl, Ann Y. Park, Yan H. Cheng, Jing Cui, Thomas Oellerich, Michael J. Lenardo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(33)
Apoptosis is a genetically regulated program of cell death that plays a key role in immune disease processes. We identified EBF4, a little-studied member of the early B cell factor (EBF) family of transcription factors, in a whole-genome CRISPR scree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13d4b609bd318264514a663aacbf26d
https://pubmed.ncbi.nlm.nih.gov/35939714
https://pubmed.ncbi.nlm.nih.gov/35939714
Publikováno v:
Journal of the American Chemical Society. 142:8291-8298
Despite decades of research, there are still many open questions surrounding the mechanisms by which enzymes catalyze reactions. Understanding all the noncovalent forces involved has the potential to allow de novo catalysis design, and as a step towa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31970553801ebe9d32069f7f1737f35b
https://doi.org/10.1021/jacs.0c00907
https://doi.org/10.1021/jacs.0c00907
Autor:
Rhea Kataria, Xiaoyang Cai, Du Tang, Henry S. Ashbaugh, Bruce C. Gibb, Kaiya Wang, Wei Yao, Larry D. Byers
Publikováno v:
Journal of the American Chemical Society. 141:6740-6747
The intrinsic structural complexity of proteins makes it hard to identify the contributions of each noncovalent interaction behind the remarkable rate accelerations of enzymes. Coulombic forces are evidently primary, but despite developments in artif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db693b1b91ab73c18602b4acdc160a41
https://doi.org/10.1021/jacs.9b02287
https://doi.org/10.1021/jacs.9b02287
Autor:
Satoshi Kubo, Jill M. Fritz, Hayley M. Raquer-McKay, Rhea Kataria, Ivan Vujkovic-Cvijin, Ahmad Al-Shaibi, Yikun Yao, Lixin Zheng, Juan Zou, Alex D. Waldman, Xinyi Jing, Taylor K. Farley, Ann Y. Park, Andrew J. Oler, Adrian K. Charles, Melanie Makhlouf, Eman H. AbouMoussa, Reem Hasnah, Luis R. Saraiva, Sundar Ganesan, Abdulrahman Ahmed Al-Subaiey, Helen Matthews, Emilio Flano, Hyun Hee Lee, Alexandra F. Freeman, Asena Pınar Sefer, Ersin Sayar, Erkan Çakır, Elif Karakoc-Aydiner, Safa Baris, Yasmine Belkaid, Ahmet Ozen, Bernice Lo, Michael J. Lenardo
Publikováno v:
Nature immunology. 23(1)
We report a pleiotropic disease due to loss-of-function mutations in RHBDF2, the gene encoding iRHOM2, in two kindreds with recurrent infections in different organs. One patient had recurrent pneumonia but no colon involvement, another had recurrent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10dfff11ac6fc2a78495279c1fbec6d2
https://pubmed.ncbi.nlm.nih.gov/34937930
https://pubmed.ncbi.nlm.nih.gov/34937930
Publikováno v:
Journal of the American Chemical Society. 142(18)
Despite decades of research, there are still many open questions surrounding the mechanisms by which enzymes catalyze reactions. Understanding all the noncovalent forces involved has the potential to allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b0f7c8d3a9ee036dd142dec427bed9f
https://pubmed.ncbi.nlm.nih.gov/32271561
https://pubmed.ncbi.nlm.nih.gov/32271561