Výsledky vyhledávání - "Rhayanna B, Gaglianone"

Reduced mitochondrial respiration and increased calcium deposits in the EDL muscle, but not in soleus, from 12-week-old dystrophic mdx mice

Autor: Tania M. Ortiga-Carvalho, Anderson Teixeira Santos, Manoel L. Costa, Thereza Quirico-Santos, Flavia Fonseca Bloise, Claudia Mermelstein, Rhayanna B Gaglianone, Wagner Seixas da Silva

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports

Mitochondria play an important role in providing ATP for muscle contraction. Muscle physiology is compromised in Duchenne muscular dystrophy (DMD) and several studies have shown the involvement of bioenergetics. In this work we investigated the mitoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6c44a0183524f1c5a0a71c1b3831b5
http://link.springer.com/article/10.1038/s41598-019-38609-4

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Persistent mdx diaphragm alterations are accompanied by increased expression and activity of calcium and muscle-specific proteins

Autor: Rhayanna B, Gaglianone, Flavia Fonseca, Bloise, Jussara, Lagrota-Candido, Claudia, Mermelstein, Thereza, Quirico-Santos

Publikováno v: Histology and histopathology. 36(7)

The mdx mouse model of Duchenne Muscular Dystrophy (DMD) presents sarcolemma instability and develops a mild multi-stage dystrophinopathy characterized by intense myonecrosis with inflammatory infiltrate at 4-weeks; muscular regeneration at 12-weeks

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d08dd3859827ccab73c036c9720b919f
https://pubmed.ncbi.nlm.nih.gov/33825181

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Comparative study of calcium and calcium-related enzymes with differentiation markers in different ages and muscle types in mdx mice

Autor: Rhayanna B, Gaglianone, Flavia Fonseca, Bloise, Tania Maria, Ortiga-Carvalho, Thereza, Quirico-Santos, Manoel Luis, Costa, Claudia, Mermelstein

Publikováno v: Histology and histopathology. 35(2)

Sarcolemma instability and increased calcium influx in muscle fibers are characteristics of the Duchenne muscular dystrophy. Excessive calcium activates calcium-dependent enzymes, such as calpains (CAPN) and matrix metalloproteases (MMP). Here, we an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79030d4ef7c58161ef99196cc62a8ef6
https://pubmed.ncbi.nlm.nih.gov/31274171

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