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pro vyhledávání: '"Rhîan G. Jacobsen"'
Autor:
Andrea Papdiné Morovicz, Fatemeh Mazloumi Gavgani, Rhîan G. Jacobsen, Malene Skuseth Slinning, Diana C. Turcu, Aurélia E. Lewis
Publikováno v:
Advances in biological regulation. 83
The phosphoinositide 3-kinase (PI3K) signalling pathway plays key roles in many cellular processes and is altered in many diseases. The function and mode of action of the pathway have mostly been elucidated in the cytoplasm. However, many of the comp
Autor:
Fatemeh, Mazloumi Gavgani, Victoria, Smith Arnesen, Rhîan G, Jacobsen, Camilla, Krakstad, Erling A, Hoivik, Aurélia E, Lewis
Publikováno v:
International Journal of Molecular Sciences
The phosphoinositide 3-kinase (PI3K) signalling pathway is highly dysregulated in cancer, leading to elevated PI3K signalling and altered cellular processes that contribute to tumour development. The pathway is normally orchestrated by class I PI3K e