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Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 6, Pp 1122-1133 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
This study aimed to explore the link between block copolymers’ interfacial properties and nanoscale carrier formation and found out the influence of length ratio on these characters to optimize drug delivery system. A library of diblock copolymers
Publikováno v:
Journal of Controlled Release
Liposomal formulations for the treatment of cancer and other diseases are the most common form of nanotechnology enabled pharmaceuticals (NEPs) submitted for market approval and in clinical application today. The accurate characterization of their ph
Autor:
Timothy J, Eyes, James I, Austerberry, Rebecca J, Dearman, Linus O, Johannissen, Ian, Kimber, Noel, Smith, Angela, Thistlethwaite, Jeremy P, Derrick
Publikováno v:
Molecular Immunology
Highlights • Aggregation of an exemplar therapeutic antibody fragment (scFv) enhances immunogenicity in vivo. • Epitope mapping reveals immunogenicity is directed to a specific epitope in aggregate species. • Molecular simulation demonstrates b
Autor:
Li J; Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China., Du Y; Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China., Su H; Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China., Cheng S; Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China., Zhou Y; Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China., Jin Y; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China., Qi XR; Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Jun; Vol. 10 (6), pp. 1122-1133. Date of Electronic Publication: 2020 Jan 20.