SSR240600 [(R)-2-(1-[2-[4-[2-[3,5-bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]-4-piperidinyl)-2-methylpropanamide], a centrally active nonpeptide antagonist of the tachykinin neurokinin 1 receptor: II. Neurochemical and behavioral characterization.

Autor: Rgis, Steinberg, Richard, Alonso, Liliane, Rouquier, Christophe, Desvignes, Jean-Claude, Michaud, Annie, Cudennec, Mireille, Jung, Jacques, Simiand, Guy, Griebel, Xavier, Emonds-Alt, Grard, Le Fur, Philippe, Soubri

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; December 2002, Vol. 303 Issue: 3 p1180-8, 9p

4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1, 3-thiazol-2-amine hydrochloride (SSR125543A), a potent and selective corticotrophin-releasing factor(1) receptor antagonist. II. Characterization in rodent models of stress-related disorders.

Autor: Guy, Griebel, Jacques, Simiand, Rgis, Steinberg, Mireille, Jung, Danielle, Gully, Pierre, Roger, Michel, Geslin, Bernard, Scatton, Jean-Pierre, Maffrand, Philippe, Soubri

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; April 2002, Vol. 301 Issue: 1 p333-45, 13p