Molecular Modeling Targeting the ACE2 Receptor with ’s Active Ingredients for Antiviral Drug Discovery against SARS-CoV-2 Infections

Autor: Zainab El Ouafi, Wajih Rhalem, Nihal Habib, Abdellah Idrissi Azami, Sofia Sehli, Najib Al Idrissi, Fadil Bakkali, Rfaki Abderrazak, Mohamed Merzouki, Imane Allali, Saaïd Amzazi, Chakib Nejjari, Hassan Ghazal

Publikováno v: Bioinformatics and Biology Insights, Vol 16 (2022)

The emergence of a novel coronavirus that later on rendered a global pandemic, caused desperation within the communities and drove increased interest in exploring medicinal plant–based therapeutics to treat and prevent severe acute respiratory synd

Externí odkaz: https://doaj.org/article/2ac5d59ba76744ac971aab8ee9a9a5d5

Design, synthesis, and computational studies of novel imidazo[1,2-a]pyrimidine derivatives as potential dual inhibitors of hACE2 and spike protein for blocking SARS-CoV-2 cell entry

Autor: Mohamed Azzouzi, Zainab El Ouafi, Omar Azougagh, Walid Daoudi, Hassan Ghazal, Soufian El Barkany, Rfaki Abderrazak, Stéphane Mazières, Abdelmalik El Aatiaoui, Adyl Oussaid

Publikováno v: Journal of Molecular Structure. 1285:135525

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9dfbef19a0e605f6f7f4ebfef722a281
https://doi.org/10.1016/j.molstruc.2023.135525

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Complete Genome Sequence of a SARS-CoV-2 Strain Sampled in Morocco in May 2020, Obtained Using Sanger Sequencing.

Autor: Rfaki A; Molecular Biology and Functional Genomics Platform, National Center for Scientific and Technical Research (CNRST), Rabat, Morocco.; Genomic Center for Human Pathologies (GENOPATH), Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco., Touil N; Genomic Center for Human Pathologies (GENOPATH), Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco.; Unité de Culture Cellulaire, CVMIT, HMI Med V, Rabat, Morocco., Hemlali M; Molecular Biology and Functional Genomics Platform, National Center for Scientific and Technical Research (CNRST), Rabat, Morocco.; Genomic Center for Human Pathologies (GENOPATH), Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco., Alaoui Amine S; Molecular Biology and Functional Genomics Platform, National Center for Scientific and Technical Research (CNRST), Rabat, Morocco.; Genomic Center for Human Pathologies (GENOPATH), Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco., Melloul M; Molecular Biology and Functional Genomics Platform, National Center for Scientific and Technical Research (CNRST), Rabat, Morocco.; Genomic Center for Human Pathologies (GENOPATH), Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco., El Alaoui MA; Molecular Biology and Functional Genomics Platform, National Center for Scientific and Technical Research (CNRST), Rabat, Morocco.; Laboratoire de Botanique et de Protection des Plantes, UFR de Mycologie, Département de Biologie, Faculté des Sciences, Université Ibn Tofail, Kenitra, Morocco., Elannaz H; Unité de Culture Cellulaire, CVMIT, HMI Med V, Rabat, Morocco., Lahlou AI; Unité de Culture Cellulaire, CVMIT, HMI Med V, Rabat, Morocco., Elouennass M; Unité de Culture Cellulaire, CVMIT, HMI Med V, Rabat, Morocco., Ennibi K; Unité de Culture Cellulaire, CVMIT, HMI Med V, Rabat, Morocco., El Fahime E; Molecular Biology and Functional Genomics Platform, National Center for Scientific and Technical Research (CNRST), Rabat, Morocco m.elfahime@gmail.com.; Genomic Center for Human Pathologies (GENOPATH), Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco.

Publikováno v: Microbiology resource announcements [Microbiol Resour Announc] 2021 May 20; Vol. 10 (20). Date of Electronic Publication: 2021 May 20.