Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Rezzan Aker"'
Publikováno v:
Epilepsy Research. 95:1-8
Lamotrigine (LTG) which has a widespread use in epilepsy treatment as an antiepileptic agent is metabolized by UDP-glucuronosyl transferase (UGT) enzymes. In this study, single nucleotide polymorphisms, P24T and L48V, of the UGT1A4 enzyme have been i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b64af8c3d7945ed41132aa4f8d8c9b
https://doi.org/10.1016/j.eplepsyres.2011.01.016
https://doi.org/10.1016/j.eplepsyres.2011.01.016
Publikováno v:
Brain Research. 1377:101-108
The existence of absence epilepsy and temporal lobe epilepsy in the same patient is not common in clinical practice. The reason why both types of seizures are rarely seen in the same patient is not well understood. Therefore, we aimed to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca09311ad0b17a5cf37984b47ec50dd
https://doi.org/10.1016/j.brainres.2010.12.066
https://doi.org/10.1016/j.brainres.2010.12.066
Autor:
Tugba Eryigit, Rezzan Aker, Mattia Maroso, Ilaria Vanzulli, Teresa Ravizza, Filiz Onat, Nihan Çarçak, Demet Akin, Annamaria Vezzani
Publikováno v:
Neurobiology of Disease; Vol 44
Neurobiology of Disease
Neurobiology of Disease, Vol 44, Iss 3, Pp 259-269 (2011)
Neurobiology of Disease
Neurobiology of Disease, Vol 44, Iss 3, Pp 259-269 (2011)
Interleukin (IL)-1β plays a crucial role in the mechanisms of limbic seizures in rodent models of temporal lobe epilepsy. We addressed whether activation of the IL-1β signaling occurs in rats with genetic absence epilepsy (GAERS) during the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f63549d968ded493c1153a4281ba8d
Publikováno v:
Neuroscience Letters. 479:74-78
Two genetic models of absence epilepsy, GAERS and WAG/Rij rat strains, are resistant to progression of partial seizures induced by amygdaloid or hippocampal kindling. Perirhinal cortex is one of the crucial areas for the secondary generalization of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74fb6b33a467c3075b0eae4f4af21b9d
https://doi.org/10.1016/j.neulet.2010.05.034
https://doi.org/10.1016/j.neulet.2010.05.034
Autor:
Berna Terzioglu, Bedia Koçyiğit-Kaymakçıoğlu, Sevim Rollas, Filiz Onat, Ayten Azizova Gurbanova, Emine Elçin Oruç-Emre, Demet Akin, Rezzan Aker, Sema Ketenci, Eren Sakalli, Kutluhan Tezcan
Publikováno v:
Medicinal Chemistry Research. 20:607-614
A series of 3,5-dimethylpyrazole derivatives, structurally related to the previously described potent ameltolide analogues, were synthesized and evaluated for their anticonvulsant activity. Ten compounds were prepared by reacting the 4-amino-3,5-dime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bddca0cf508b393c170fb0c14078d098
https://doi.org/10.1007/s00044-010-9358-6
https://doi.org/10.1007/s00044-010-9358-6
Publikováno v:
Epilepsy Research. 81:211-219
Summary Purpose WAG/Rij and GAERS rats show delays or resistance to secondary generalization of limbic seizures during amygdaloid kindling. In this study, we aimed to evaluate the kindling from a different limbic site, hippocampus, and to compare its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ed68549a892f70adadd8c3a669ba3c
https://doi.org/10.1016/j.eplepsyres.2008.06.004
https://doi.org/10.1016/j.eplepsyres.2008.06.004
Publikováno v:
The Journal of Neuroscience. 28:7828-7836
We showed previously that genetic absence epilepsy rats from Strasbourg (GAERS) resist secondary generalization of focal limbic seizures after electrical kindling. We now investigate the effect of intra-amygdaloid injection of kainic acid, as another
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8bcca03f6cea25486d9ec55c7889f2
https://doi.org/10.1523/jneurosci.1097-08.2008
https://doi.org/10.1523/jneurosci.1097-08.2008
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 2, Pp 301-309 (2008)
The posterior part of the hypothalamus plays a vital role in the homeostatic processes of the internal environment, including blood pressure and heart rate regulation, by means of γ-aminobutyric acid (GABA)ergic and glutamatergic neurotransmission.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817d0f5a29e0016923ef828c77b85772
http://www.sciencedirect.com/science/article/pii/S1347861319315269
http://www.sciencedirect.com/science/article/pii/S1347861319315269
Autor:
Rezzan Aker, Aydan E. Özkaynakçi, Filiz Onat, Ümit Şehirli, Hasan Raci Yananli, Safiye Çavdar, Yusuf Ozgur Cakmak, Hazan B. Özyurt, Erdinç Saka
Publikováno v:
Brain Research. 1111:213-221
The aim of the present study was to investigate the effect of local injections of the GABA(A) receptor antagonist, bicuculline, into the rostral and caudal parts of the thalamic reticular nucleus (TRN), on the generation of spike-and-wave discharges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e3d8d6f36d8885e4bb751dc844ca51
https://doi.org/10.1016/j.brainres.2006.06.118
https://doi.org/10.1016/j.brainres.2006.06.118
Publikováno v:
Brain Research. 968:219-226
Dorsomedial (DMH) and paraventricular nuclei (PVN) are two important hypothalamic structures involved in the central regulation of cardiovascular regulation. L-Glutamic acid and gamma-aminobutyric acid (GABA) were demonstrated to elicit cardiovascula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c06bd09c7ac1fb17e0705b92533308
https://doi.org/10.1016/s0006-8993(03)02241-8
https://doi.org/10.1016/s0006-8993(03)02241-8