Single cell expression and chromatin accessibility of the Toxoplasma gondii lytic cycle identifies AP2XII-8 as an essential ribosome regulon driver.

Autor: Lou J; Department of Biology, Boston College, Chestnut Hill, MA, USA., Rezvani Y; Department of Mathematics, University of Massachusetts Boston, Boston, MA, USA.; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, MA, USA., Arriojas A; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, MA, USA., Wu Y; Department of Biology, Boston College, Chestnut Hill, MA, USA., Shankar N; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, MA, USA., Degras D; Department of Mathematics, University of Massachusetts Boston, Boston, MA, USA., Keroack CD; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Department of Molecular Microbiology and Immunology, Brown University, Providence, RI, USA., Duraisingh MT; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA, USA., Zarringhalam K; Department of Mathematics, University of Massachusetts Boston, Boston, MA, USA. kourosh.zarringhalam@umb.edu.; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, MA, USA. kourosh.zarringhalam@umb.edu., Gubbels MJ; Department of Biology, Boston College, Chestnut Hill, MA, USA. gubbelsj@bc.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Aug 28; Vol. 15 (1), pp. 7419. Date of Electronic Publication: 2024 Aug 28.

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The extracellular milieu of Toxoplasma’s lytic cycle drives lab-adaptation and promotes changes in lipid metabolism primarily driven by transcriptional reprogramming

Autor: Kourosh Zarringhalam, Andrew Farrell, Amir Vajdi, Primo Va, Marc-Jan Gubbels, Rezvani Y, Gabor T. Marth

To map host-independent in vitro virulence traits of Toxoplasma gondii, evolve and resequencing (E&R) during the lab-adaption was applied. Phenotypic assessments of the lytic cycle revealed that only traits needed in the extracellular milieu evolved.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df616ee17145fb2369abee4b6a1b2d26
https://doi.org/10.1101/2021.03.09.434570

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Antibacterial effect of an herbal toothpaste containing Bamboo salt: a randomized double-blinded controlled clinical trial.

Autor: Biria M; Department of Pediatric Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Rezvani Y; Department of Pediatric Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Roodgarian R; Department of Pediatric Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Rabbani A; Dental Research Center, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Iranparvar P; Department of Pediatric Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran. dr.p.iranparvar@sbmu.ac.ir.

Publikováno v: BMC oral health [BMC Oral Health] 2022 May 19; Vol. 22 (1), pp. 193. Date of Electronic Publication: 2022 May 19.