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Genital Tract, Cord Blood, and Amniotic Fluid Exposures of Seven Antiretroviral Drugs during and after Pregnancy in Human Immunodeficiency Virus Type 1-Infected Women

Autor: Tappouni, H. L., Fiscus, S. A., Horton, A. L., Yeh, R. F., Patterson, K. B., Kashuba, A. D. M., Chen, Y.-C., Dumond, J. B., Vourvahis, M., Tien, H.-C., Rezk, N. L.

The objective of the study was to measure antiretroviral exposures in four physiological compartments during pregnancy, delivery, and postpartum. This prospective, open-label, longitudinal study collected paired blood plasma (BP) and genital tract (G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c0d820b67dbd3211644026b920610ba

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Suppression of Human Immunodeficiency Virus Type 1 (HIV-1) Viremia with Reverse Transcriptase and Integrase Inhibitors, CD4+ T-Cell Recovery, and Viral Rebound upon Interruption of Therapy in a New Model for HIV Treatment in the Humanized Rag2-/- c-/- Mouse

Autor: Choudhary, S. K., Ince, W. L., Margolis, D. M., Kashuba, A. D. M., Swanstrom, R., Cheema, M., Zhang, L., Rezk, N. L., Su, L.

A small animal model that reproduces human immunodeficiency virus type 1 (HIV-1) pathogenesis may allow modeling of new therapeutic strategies in ways not approachable in mononuclear cell culture. We find that, as in humans, combination antiretrovira

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e52172ffc5bb4b5d875389f20f47e110

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