Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Reza Sheikhnejad"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115299- (2023)
Genomic DNA sequences provide unique target sites, with high druggability value, for treatment of genetically-linked diseases like cancer. B-cell lymphoma protein-2 (BCL-2) prevents Bcl-2-associated X protein (BAX) and Bcl-2 antagonist killer 1 (BAK)
Externí odkaz:
https://doaj.org/article/cfd217949a554599a840e61aa07fc0d7
Autor:
Faezeh Afshin, Mousa Bohlooli, Ali Maghsoudi, Reza Sheikhnejad, Mostafa Khajeh, Ali Khatibi, Mansour Ghaffari-Moghaddam, Fatemeh Ghamari, Nader Sheibani
Publikováno v:
Journal of Food and Bioprocess Engineering, Vol 5, Iss 2, Pp 189-194 (2022)
Breast cancer is the most common form of cancer in women, and the second leading causes of death in the world. Clinical efficacy of chemotherapy is limited due to side effects, toxicity, and drug resistance. Plant-derived anticancer drugs are new pro
Externí odkaz:
https://doaj.org/article/a4f6a312b5694a4abe46f54b3568687b
Autor:
Maryam Nikkhah, Ahmad Moshaii, Saman Hosseinkhani, Mohamad Hassan Fouani, Somayeh Karimi, Reza Sheikhnejad
Publikováno v:
International Journal of Nanomedicine. 15:1693-1708
Introduction Cancer treatment using functionalized vehicles in order to block involved genes has attracted a remarkable interest. In this study, we investigated the cellular uptake and cytotoxic effects of three sizes of anti Bcl-2 DNAi-conjugated go
Publikováno v:
International Journal of Cancer. 143:2017-2028
Modulating cancer causing genes with nucleic acid based-molecules as cutting-edge approaches need efficient delivery systems to succeed in clinic. Herein, we report design and fabrication of a novel tissue penetrating peptideticle with charge-structu
Autor:
Saman Hosseinkhani, Reza Sheikhnejad, Mehdi Dadmehr, Yasaman-Sadat Borghei, Morteza Hosseini, Mohammad Reza Ganjali
Publikováno v:
Analytica Chimica Acta. 904:92-97
A simple but highly sensitive colorimetric method was developed to detect cancer cells based on aptamer-cell interaction. Cancer cells were able to capture nucleolin aptamers (AS 1411) through affinity interaction between AS 1411 and nucleolin recept
Publikováno v:
Biosensors and Bioelectronics. 73:108-113
Epigenetic changes such as DNA methylation of CpG islands located in the promoter region of some tumor suppressor genes are very common in human diseases such as cancer. Detection of aberrant methylation pattern could serve as an excellent diagnostic
Publikováno v:
Scientific Reports
Several tissue specific non-viral carriers have been developed for gene delivery purposes. However, the inability to escape endosomes, undermines the efficacy of these carriers. Researchers inspired by HIV and influenza virus, have randomly used Gp41
Autor:
Reza Sheikhnejad, Morteza Hosseini, Saman Hosseinkhani, Morteza Pirali Hamedani, Mohammad Reza Ganjali, Mehdi Khoobi, Mehdi Dadmehr, Hadi Behzadi
Publikováno v:
Biosensors and Bioelectronics. 60:35-44
A very sensitive and convenient fluorescence nanobiosensor for rapid detection of DNA methylation based on Fe3O4/Au core/shell nanoparticles has been developed. Specific site of CpG islands of adenomatous polyposis coli (APC), a well studied tumor su
Publikováno v:
Amino acids. 46(4)
We describe the design and synthesis of some hypothetical heptapeptides specifically to overcome the neoplastic activity of ras oncogene and their anti-cancer activities were studied. To improve the anti-cancer activity of the synthesized peptides, t
Publikováno v:
European Journal of Cancer. 61:S208