Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Reza Sedaghat-Herati"'
Autor:
Amine Abderrezak, Philippe Bourassa, Jean-Sebastian Mandeville, Reza Sedaghat-Herati, Heidar-Ali Tajmir-Riahi
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33102 (2012)
Synthetic polymers of a specific shape and size play major role in drug delivery systems. Dendrimers are unique synthetic macromolecules of nanometer dimensions with a highly branched structure and globular shape with potential applications in gene a
Externí odkaz:
https://doaj.org/article/665f53168cd74b278d4fe7228a2a96be
Publikováno v:
The Journal of Physical Chemistry B. 123:666-674
Dendrimers are well-defined, highly branched, synthetic three-dimensional molecules with a large number of reactive end groups. PAMAM dendrimers form stable complexes with DNA chemistries and constitute an important class of nonviral, cationic vector
Publikováno v:
European Polymer Journal. 159:110747
Among cationic polymers, chitosan (CS) is a promising non-viral vector due to its biocompatibility, biodegradability and safety profile. However, its application for gene delivery is hindered by its poor solubility at physiological pH. In this study,
Autor:
Wesley A Dowler, Jacob Robison, Xiaozheng Dou, Jonathan J. Fury, Reza Sedaghat-Herati, Robert K. Delong
Publikováno v:
Journal of Macromolecular Science, Part A. 52:30-38
The design and synthesis of novel copolymers consisting of a linear block of methoxypoly(ethylene glycol) (mPEG) and a dendrimeric poly(ether-sulfide) block with potential applications in drug and gene delivery are described. The copolymers bear hydr
Autor:
Juan Reyes-Reveles, Reza Sedaghat-Herati, John M. Dean, Robert K. Delong, Kartik Ghosh, Ashley Schaeffer, Wesley A Dowler, Hannah E Gann, Thomas D Greene, Stephen Kramer, David R Gilley
Publikováno v:
Biomacromolecules. 14:4108-4115
Dendrimer chemistries have virtually exploded in recent years with increasing interest in this class of polymers as gene delivery vehicles. An effective nucleic acid delivery vehicle must efficiently bind its cargo and form physically stable complexe
Publikováno v:
Journal of Macromolecular Science, Part A. 50:1113-1120
The design and synthesis of novel copolymers which consist of a linear methoxypoly(ethylene glycol) block and a dendrimeric poly(ester-sulfide) block with potential applications in drug delivery are described. The copolymers bear hydroxyl or alkene f
Publikováno v:
Macromolecular Chemistry and Physics. 206:1981-1987
A new poly(ethylene glycol) derivative, 3-[methoxypoly(oxyethylene)]methylene furan, I, was prepared from the reaction of 3-furanmethanol with the mesylate of methoxypoly(oxyethylene) in tetrahydrofuran. The degree of end-group conversion, as determi
Publikováno v:
Journal of Polymer Science Part A: Polymer Chemistry. 43:1895-1902
Diels–Alder reactions of 5-[methoxypoly(oxyethylene)]-(3E)-1,3-pentadiene (1a) with maleic anhydride, diethyl acetylenedicarboxylate (DADC), and acrolein were investigated for the synthesis of new poly(ethylene glycol) derivatives. To facilitate th
Autor:
Ramin S. Herati, Reza Sedaghat Herati
Publikováno v:
Journal of Polymer Science Part A: Polymer Chemistry. 42:1934-1938
A new poly(ethylene glycol) derivative, 1-methoxypoly(oxyethylene)benzocyclobutene (1) was prepared from the reaction of 1-benzocyclobutenyl 1-hydroxyethyl ether with mesylate of methoxypoly(oxyethylene) in tetrahydrofuran. The degree of end-group co
Publikováno v:
Polymer Bulletin. 48:221-224
A new method to synthesize vinyl ethers of methoxyoligooxyethylene, I, and methoxypoly(oxyethylene), II, is described. In this work, these derivatives were prepared by reacting the alkoxide of ethylene glycol vinyl ether with the tosylate (or mesylat