Raja 42, a novel gamma lactam compound, is effective against Clostridioides difficile.

Autor: Alexis Fong, Megan Ross, Justin Boudreau, Reza Nokhbeh, Kim Tilbe, Hoyun Lee

Publikováno v: PLoS ONE, Vol 16, Iss 9, p e0257143 (2021)

Clostridioides difficile infection (CDI) is the primary cause of hospital-acquired diarrhea, and responsible for over 500,000 enteric infections a year in the United States alone. Although most patients with CDI are successfully treated with metronid

Externí odkaz: https://doaj.org/article/81d1e77f48bb42818e9e32cdc31980c4

IRES-mediated translation in bacteria

Autor: Sarah Takallou, Nathalie Puchacz, Danielle Allard, Kamaledin B. Said, Mohammad Reza Nokhbeh, Bahram Samanfar, Ashkan Golshani

Publikováno v: Biochemical and biophysical research communications. 641

Despite the similarity in fundamental goals of translation initiation between different domains of life, it is one of the most phylogenetically diverse steps of the central dogma of molecular biology. In a classical view, the translation signals for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98cb31540bea11039eb64a61581f0fb5
https://pubmed.ncbi.nlm.nih.gov/36527744

Synthesis, thermal properties, spectroscopic characterization and DFT computations of 1,3-propanediylbis (triphenylphosphonium) peroxydisulfate as a new oxidative agent

Autor: Mostafa Gholizadeh, Faezeh Makari, Seyed Reza Nokhbeh

Publikováno v: Chemical Reports. 2:144-155

Thermal properties and spectroscopic characterization of new synthesized 1,3-propanediylbis (triphenylphosphonium) peroxydisulfate as a member of phosphonium persulfates were studied. 1H, 13C, 31P NMR and FT-IR were used to structural characterizatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da70c2a6c286f555fc0b5a49dd2130eb
https://doi.org/10.25082/cr.2020.01.004

Crystal structure, characterization, Hirshfeld surface analysis and DFT studies of two [propane 3-bromo-1-(triphenyl phosphonium)] cations containing bromide (I) and tribromide (II) anions: The anion (II) as a new brominating agent for unsaturated compounds

Autor: Mostafa Gholizadeh, Seyed Reza Nokhbeh, Hazel A. Sparkes, Alireza Salimi

Publikováno v: Nokhbeh, S R, Gholizadeh, M, Salimi, A & Sparkes, H A 2019, ' Crystal structure, characterization, Hirshfeld surface analysis and DFT studies of two [propane 3-bromo-1-(triphenyl phosphonium)] cations containing bromide (I) and tribromide (II) anions : The anion (II) as a new brominating agent for unsaturated compounds ', Journal of Molecular Structure, vol. 1195, pp. 542-554 . https://doi.org/10.1016/j.molstruc.2019.05.127

In this study, propane 3-bromo-1- (triphenyl phosphonium) bromide, I, and propane 3-bromo-1- (triphenyl phosphonium) tribromide, II, (II as a new brominating agent) were synthesized and characterized by 1H NMR, 13C NMR, 31P NMR, FT-IR, spectroscopy,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb2e17305903764c0bc9a89d2d97e62
https://doi.org/10.1016/j.molstruc.2019.05.127

Raja 42, a novel gamma lactam compound, is effective against Clostridioides difficile

Autor: Megan Ross, Reza Nokhbeh, Hoyun Lee, Alexis Fong, Kim Tilbe, Justin Boudreau

Publikováno v: PLoS ONE, Vol 16, Iss 9, p e0257143 (2021)
PLoS ONE

Clostridioides difficile infection (CDI) is the primary cause of hospital-acquired diarrhea, and responsible for over 500,000 enteric infections a year in the United States alone. Although most patients with CDI are successfully treated with metronid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f699fdb3d83b817776a0af5cee537c0
https://doi.org/10.1371/journal.pone.0257143