Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Reza Naghavian"'
Autor:
Reza Naghavian, Kamran Ghaedi, Abbas Kiani-Esfahani, Mazdak Ganjalikhani-Hakemi, Masoud Etemadifar, Mohammad Hossein Nasr-Esfahani
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124555 (2015)
One of the main issues in pathogenesis of MS is Th17/Treg imbalance. There are growing interests in nominating miRNAs involved in Th17 cell differentiation, suggesting them as new therapeutic agents that may reduce progression of different autoimmune
Externí odkaz:
https://doaj.org/article/f719106e322c4f8890fde23cd37732db
Autor:
Roland Martin, Patrick Roth, Michael Weller, Luca Regli, Bernd Bodenmiller, Erich F. Greiner, Holger Moch, Mireia Sospedra, Andreas Lutterotti, Catherine J. Wu, Ron McKay, Joo Heon Shin, Barbara Schrörs, Susanne Dettwiler, Elisabeth Rushing, Daniel Schulz, Ivan Jelcic, Gioele Medici, Paula Tomas Ojer, Magdalena Foege, Carla Sellés Moreno, Reza Naghavian, Nora C. Toussaint, Marian C. Neidert, Tobias Weiss, Jian Wang
Designed mutations increase the stimulatory strength of D-neopeptides above N-peptides. (A) TILs were stimulated with 5 μM class I-peptides, including N-peptides and D-neopeptides, for 5 days. 5 replicate wells were tested for proliferation, and pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ceb25277d9242b2898736907629a9d6
https://doi.org/10.1158/1078-0432.22488566
https://doi.org/10.1158/1078-0432.22488566
Autor:
Roland Martin, Patrick Roth, Michael Weller, Luca Regli, Bernd Bodenmiller, Erich F. Greiner, Holger Moch, Mireia Sospedra, Andreas Lutterotti, Catherine J. Wu, Ron McKay, Joo Heon Shin, Barbara Schrörs, Susanne Dettwiler, Elisabeth Rushing, Daniel Schulz, Ivan Jelcic, Gioele Medici, Paula Tomas Ojer, Magdalena Foege, Carla Sellés Moreno, Reza Naghavian, Nora C. Toussaint, Marian C. Neidert, Tobias Weiss, Jian Wang
Predicted TSA/TAA-derived N-peptides and D-neopeptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076b20fe5359c6604ca16659aeb889ad
https://doi.org/10.1158/1078-0432.22488554.v1
https://doi.org/10.1158/1078-0432.22488554.v1
Autor:
Roland Martin, Patrick Roth, Michael Weller, Luca Regli, Bernd Bodenmiller, Erich F. Greiner, Holger Moch, Mireia Sospedra, Andreas Lutterotti, Catherine J. Wu, Ron McKay, Joo Heon Shin, Barbara Schrörs, Susanne Dettwiler, Elisabeth Rushing, Daniel Schulz, Ivan Jelcic, Gioele Medici, Paula Tomas Ojer, Magdalena Foege, Carla Sellés Moreno, Reza Naghavian, Nora C. Toussaint, Marian C. Neidert, Tobias Weiss, Jian Wang
Purpose:The low mutational load of some cancers is considered one reason for the difficulty to develop effective tumor vaccines. To overcome this problem, we developed a strategy to design neopeptides through single amino acid mutations to enhance th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194ce836ba5d5bdee824d491fbddf768
https://doi.org/10.1158/1078-0432.c.6532760
https://doi.org/10.1158/1078-0432.c.6532760
Autor:
Roland Martin, Patrick Roth, Michael Weller, Luca Regli, Bernd Bodenmiller, Erich F. Greiner, Holger Moch, Mireia Sospedra, Andreas Lutterotti, Catherine J. Wu, Ron McKay, Joo Heon Shin, Barbara Schrörs, Susanne Dettwiler, Elisabeth Rushing, Daniel Schulz, Ivan Jelcic, Gioele Medici, Paula Tomas Ojer, Magdalena Foege, Carla Sellés Moreno, Reza Naghavian, Nora C. Toussaint, Marian C. Neidert, Tobias Weiss, Jian Wang
Supplementary Table 1. Somatic mutations of the patient's glioblastoma; Supplementary Table 2. See Excel File; Supplementary Table 3. Literature-derived, glioblastoma-associated TAAs; Supplementary Table 4. See Excel File; Supplementary Table 5. Over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5715d4604cc355dbcad734a421599798
https://doi.org/10.1158/1078-0432.22488560.v1
https://doi.org/10.1158/1078-0432.22488560.v1
Autor:
Jian Wang, Tobias Weiss, Marian C. Neidert, Nora C. Toussaint, Reza Naghavian, Carla Sellés Moreno, Magdalena Foege, Paula Tomas Ojer, Gioele Medici, Ivan Jelcic, Daniel Schulz, Elisabeth Rushing, Susanne Dettwiler, Barbara Schrörs, Joo Heon Shin, Ron McKay, Catherine J. Wu, Andreas Lutterotti, Mireia Sospedra, Holger Moch, Erich F. Greiner, Bernd Bodenmiller, Luca Regli, Michael Weller, Patrick Roth, Roland Martin
Publikováno v:
Clinical Cancer Research, 28 (24)
Purpose: The low mutational load of some cancers is considered one reason for the difficulty to develop effective tumor vaccines. To overcome this problem, we developed a strategy to design neopeptides through single amino acid mutations to enhance t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8dbb57d4e9eeaff591ab97ad18c938
https://www.zora.uzh.ch/id/eprint/221622/
https://www.zora.uzh.ch/id/eprint/221622/
Autor:
Josefine Ruder, María José Docampo, Jordan Rex, Simon Obahor, Reza Naghavian, Antonia M.S. Müller, Urs Schanz, Ilijas Jelcic, Roland Martin
Publikováno v:
Science Translational Medicine. 14
Autologous hematopoietic stem cell transplantation (aHSCT) is a highly effective treatment of multiple sclerosis (MS). It depletes autoreactive cells and subsequently renews adaptive immune cells. The possible proinflammatory potential of surviving T
Autor:
Anna Raykova, Guido Ferlazzo, Christine Engelmann, Julia Rühl, Donal McHugh, Hana Zdimerova, Christian Münz, Cornelia Gujer, Jan D. Lünemann, Roland Martin, Bithi Chatterjee, Anita Murer, Gaetana Pezzino, Reza Naghavian, Riccarda Capaul, Nicole Caduff, Yun Deng, Andrea Zbinden
Immune responses to Epstein-Barr virus (EBV) infection synergize with the main genetic risk factor HLA-DRB1*15:01 (HLA-DR15) to increase the likelihood to develop the autoimmune disease multiple sclerosis (MS) at least sevenfold. In order to gain ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c7a406865af3e0a27030d09da43a30
https://www.zora.uzh.ch/id/eprint/192918/
https://www.zora.uzh.ch/id/eprint/192918/
Autor:
Andrea Zbinden, Donal McHugh, Christine Engelmann, Bithi Chatterjee, Jan D. Lünemann, Reza Naghavian, Gaetana Pezzino, Hana Zdimerova, Anna Raykova, Guido Ferlazzo, Nicole Caduff, Yun Deng, Riccarda Capaul, Cornelia Gujer, Christian Münz, Anita Murer, Roland Martin, Julia Rühl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::670f6b323401e38f4fa5aed9c185e6a1
https://doi.org/10.1002/eji.202048655/v2/response1
https://doi.org/10.1002/eji.202048655/v2/response1
Autor:
Carolina Cruciani, Yingdong Zhao, Jian Wang, Lena Mühlenbruch, Wolfgang Faigle, William W. Kwok, Mathias Hauri-Hohl, Julie T. Nguyen, Mireia Sospedra, Roland Martin, Christian Münz, Ivan Jelcic, Magdalena Foege, Jar-How Lee, Veronika Haunerdinger, Andreas Lutterotti, Richard Reynolds, Nora C. Toussaint, Thomas Eiermann, Thomas M.C. Binder, Laura Fuentes-Font, Lennart Opitz, Hans-Georg Rammensee, Stefan Stevanovic, Reza Naghavian
Publikováno v:
Cell
1281.e20
Cell, 183 (5)
1281.e20
Cell, 183 (5)
Summary The HLA-DR15 haplotype is the strongest genetic risk factor for multiple sclerosis (MS), but our understanding of how it contributes to MS is limited. Because autoreactive CD4+ T cells and B cells as antigen-presenting cells are involved in M